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    Defect classification apparatus
    5.
    发明授权
    Defect classification apparatus 有权
    缺陷分类仪

    公开(公告)号：US08977580B2

    公开(公告)日：2015-03-10

    申请号：US13703536

    申请日：2011-06-08

    申请人： Kazunori Anayama ,  Tetsuya Yadoguchi ,  Toshiyuki Suzuma ,  Eiji Honda ,  Takahiro Okada ,  Shinya Yoshikawa ,  Tamotsu Nishimine

    发明人： Kazunori Anayama ,  Tetsuya Yadoguchi ,  Toshiyuki Suzuma ,  Eiji Honda ,  Takahiro Okada ,  Shinya Yoshikawa ,  Tamotsu Nishimine

    IPC分类号： G06F15/18 ,  G06N99/00 ,  G01N21/892 ,  G01N21/952 ,  G06T7/00 ,  G01N21/89

    CPC分类号： G06N99/005 ,  G01N21/892 ,  G01N21/952 ,  G01N2021/8918 ,  G06T7/0004 ,  G06T2207/20081 ,  G06T2207/30136

    摘要： The present invention has its objective to provide a defect classification apparatus which suppresses over-fitting and accurately classify the defect type of a defect. A defect classification apparatus is provided in which a data point indicating feature information of a defect to be classified having an unknown defect type is mapped to a point in a mapping space having a dimensional number higher than the number of features constituting the feature information, and the defect type of the defect to be classified is classified based on in which of two regions of defect type, which are formed by separating the mapping space by a decision boundary, the mapped point is located, wherein a discriminant function indicating the decision boundary is determined by adopting a weight which minimizes the sum of the classification error, which corresponds to the accuracy in classifying a training defect dataset, and a regularization term, which has a positive correlation with the dimensional number of the decision boundary, as the weight for each feature constituting the discriminant function.

    摘要翻译： 本发明的目的是提供一种缺陷分类装置，其能够抑制缺陷的缺陷类型的过度拟合和精确分类。 提供了一种缺陷分类装置，其中指示具有未知缺陷类型的要分类的缺陷的特征信息的数据点被映射到具有高于构成特征信息的特征数的维度数的映射空间中的点，以及 基于通过将映射空间分离为决策边界而形成的两个缺陷类型区域中的哪一个进行分类的缺陷类型，映射点位于其中，其中指示判定边界的判别函数为 通过采用最小化对应于训练缺陷数据集的分类精度的分类误差和与决策边界的维数有正相关关系的正则化项的权重作为每个 特征构成判别函数。

    Triazole derivative and use thereof
    8.
    发明授权
    Triazole derivative and use thereof 失效
    三唑衍生物及其用途

    公开(公告)号：US07803822B2

    公开(公告)日：2010-09-28

    申请号：US11887936

    申请日：2006-04-06

    申请人： Keiji Kubo ,  Mamoru Tobisu ,  Eiji Honda ,  Takahiko Taniguchi ,  Yoshiyuki Fukase ,  Masaki Kawamura ,  Masaharu Nakayama

    发明人： Keiji Kubo ,  Mamoru Tobisu ,  Eiji Honda ,  Takahiko Taniguchi ,  Yoshiyuki Fukase ,  Masaki Kawamura ,  Masaharu Nakayama

    IPC分类号： A61K31/41 ,  C07D249/00

    CPC分类号： C07D249/06 ,  C07D401/04 ,  C07D401/10 ,  C07D401/12 ,  C07D403/06 ,  C07D403/12 ,  C07D405/12 ,  C07D409/04 ,  C07D409/12 ,  C07D411/12 ,  C07D413/06 ,  C07D413/12 ,  C07D417/06 ,  C07D417/12 ,  C07D471/04 ,  C07D487/04

    摘要： The present invention relates to a thrombin receptor antagonist containing a compound represented by the formula (I) wherein R1a, R1b and R2 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, or an optionally substituted alkoxy, R3 is a group represented by the formula —NHCOR4, —NHSO2R5, —NHCON(R6a)(R6b), —NHCOOR7 or —CONHR8 wherein R4, R5, R6a, R6b, R7 and R8 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group and the like), ring A is monocyclic aromatic ring optionally further having substituent(s), R1a and R1b are optionally bonded to each other to form an optionally substituted nitrogen-containing non-aromatic heterocycle, or a salt thereof or a prodrug thereof. The thrombin receptor antagonist of the present invention has a thrombin receptor (particularly PAR-1) antagonistic action and is useful for the prophylaxis or treatment of PAR-1 mediated pathological condition or disease.

    摘要翻译： 本发明涉及含有式（I）表示的化合物的凝血酶受体拮抗剂，其中R1a，R1b和R2各自为氢原子，任选取代的烃基，任选取代的杂环基或任选取代的烷氧基，R 3 是由式-NHCOR4，-NHSO2R5，-NHCON（R6a）（R6b），-NHCOOR7或-CONHR8表示的基团，其中R4，R5，R6a，R6b，R7和R8各自为氢原子，任选取代的烃基 ，任选取代的杂环基等），环A是任选进一步具有取代基的单环芳环，R 1a和R 1b任选地彼此键合以形成任选取代的含氮非芳族杂环或盐 或其前药。 本发明的凝血酶受体拮抗剂具有凝血酶受体（特别是PAR-1）拮抗作用，可用于预防或治疗PAR-1介导的病理状态或疾病。