公开(公告)号：US09039616B2

公开(公告)日：2015-05-26

申请号：US13201156

申请日：2010-02-11

申请人： Gangming Luo ,  Jonathan J. Kaufman

发明人： Gangming Luo ,  Jonathan J. Kaufman

IPC分类号： A61B5/103 ,  A61B8/08 ,  A61B5/00 ,  A61B6/00 ,  A61B8/00

CPC分类号： A61B8/0875 ,  A61B5/00 ,  A61B5/0055 ,  A61B6/00 ,  A61B8/4209

摘要： An invention is disclosed for locating a region of interest (ROI) in the radius. A method and apparatus are disclosed that use a pair of ultrasound transducers for ultrasound assessment of various properties of bone. The invention includes positioning the transducers on the anterior-posterior (dorsal and ventral) sides of a forearm of an individual. The positioning is based on the forearm length, and a selected percentage of this length at which the ROI is desired. In a presently preferred embodiment of the invention, the ROI is defined as the ⅓rd location. An arm is placed in an ultrasound fixture which has a first surface, a second surface with a raised portion against which the ulna styloid process is placed, and a third surface on which the elbow is placed. The distance between the raised portion of the second surface and the centerlines of the pair of ultrasound transducers is adjustable. The positioning so obtained leads to the ability to make both (i) reproducible measurements and (ii) to be able to compare the results obtained in one person with another, because relatively analogous portions of the radii are assessed in both. In an alternative embodiment of the invention, a single transducer is positioned similarly on the forearm, operating in pulse-echo mode.

摘要翻译： 公开了一种用于在半径中定位感兴趣区域（ROI）的发明。 公开了一种使用一对超声波换能器来超声评估骨骼各种性质的方法和装置。 本发明包括将换能器定位在个体前臂的前 - 后（背侧和腹侧）侧。 定位是基于前臂长度，以及期望ROI的长度的选定百分比。 在本发明的当前优选实施例中，ROI被定义为第1/3位置。 手臂放置在具有第一表面的超声波固定器中，具有突出部分的第二表面，尺骨乳突过程被放置在其上，第三表面设置有肘部。 第二表面的凸起部分与一对超声换能器的中心线之间的距离是可调节的。 如此获得的定位使得能够使（i）可再现的测量和（ii）能够将在一个人中获得的结果与另一个人的结果进行比较，因为在两者中评估半径的相对类似的部分。 在本发明的替代实施例中，单个换能器类似地定位在前臂上，以脉冲回波模式操作。

公开(公告)号：US20050197576A1

公开(公告)日：2005-09-08

申请号：US11063012

申请日：2005-02-22

申请人： Gangming Luo ,  Robert Siffert ,  William Johnson ,  Ronald Altman ,  Jonathan Kaufman

发明人： Gangming Luo ,  Robert Siffert ,  William Johnson ,  Ronald Altman ,  Jonathan Kaufman

IPC分类号： A61B8/00 ,  A61B8/08

CPC分类号： A61B8/0875

摘要： A method for the assessment of various properties of bone is provided. The method includes applying a pair of ultrasound transducers to skin on opposite sides of the bone and generating an ultrasound signal and directing the signal through both the bone to obtain a bone output signal. The method further includes establishing a set of parameters associated with the bone output signal and then further processing the parameters in order to obtain the desired bone property. Two novel parameters are also disclosed, namely the net time delay (NTD) and mean time duration (MTD) parameters. An apparatus for the assessment of various properties of bone is also provided. The apparatus includes a pair of ultrasound transducers which may be single-element transducers or array transducers in any combination. The apparatus further includes various computer hardware components and computer software for generating and directing the ultrasound signal, establishing the parameter set and performing the processing. In addition, an apparatus that is battery powered, handheld, and portable and operates in real time is also provided.

摘要翻译： 提供了一种用于评估骨骼各种性质的方法。 该方法包括将一对超声换能器应用于骨的相对侧上的皮肤并产生超声信号并将信号引导通过骨骼以获得骨输出信号。 该方法还包括建立与骨输出信号相关联的一组参数，然后进一步处理参数以获得期望的骨性质。 还公开了两个新颖的参数，即净时延（NTD）和平均持续时间（MTD）参数。 还提供了用于评估骨的各种性质的装置。 该装置包括一对超声换能器，其可以是任何组合的单元件换能器或阵列换能器。 该装置还包括用于生成和指导超声信号的各种计算机硬件组件和计算机软件，建立参数组并执行处理。 此外，还提供了电池供电，手持式和便携式并且实时操作的装置。

公开(公告)号：US09727046B2

公开(公告)日：2017-08-08

申请号：US14625691

申请日：2015-02-19

申请人： Gangming Luo ,  Jonathan J. Kaufman

发明人： Gangming Luo ,  Jonathan J. Kaufman

IPC分类号： G05B19/42 ,  G05B19/18 ,  G06F19/00 ,  G05B19/042

CPC分类号： G05B19/0426 ,  G05B19/0423 ,  G05B2219/21086 ,  G05B2219/21122

摘要： A system for monitoring or controlling a remote programmable device is provided. The system includes a server configured for connection to the programmable device and a local computing device. The server includes code that establishes a data structure accessible by both devices and including a plurality of user configurable records. The server receives instructions from the local device to configure each record as an input, output or input/output channel corresponding to input, output or input/output parameters of the programmable device and to define input values for the input channels and input/output channels. The server transmits the input values and input/output values to the programmable device and receives output values and input/output values from the programmable device for transmission to the local computing device.

公开(公告)号：US09615814B2

公开(公告)日：2017-04-11

申请号：US13015141

申请日：2011-01-27

申请人： Gangming Luo ,  Jonathan J. Kaufman

发明人： Gangming Luo ,  Jonathan J. Kaufman

IPC分类号： A61B8/08

CPC分类号： A61B8/0875

摘要： An invention is disclosed for locating a region of interest in the calcaneus. A pair of ultrasound transducers are positioned on the medial and lateral sides of the heel, respectively. The positioning is based on a size of a portion of the body of a subject upon whom the ultrasound assessment of the calcaneus is to be made. In a presently preferred embodiment, the length of the foot from the back to the head of the first metatarsal is used in conjunction with a proportionality constant and an angle, to position the pair of transducers. The positioning so obtained facilitates (i) reproducible measurements and (ii) comparisons of the results obtained in one person with another, because relatively analogous portions of the highly heterogeneous calcanei are assessed in both. In an alternative embodiment, a single transducer is positioned similarly on the heel, operating in pulse-echo mode.

公开(公告)号：US08202219B2

公开(公告)日：2012-06-19

申请号：US11063012

申请日：2005-02-22

申请人： Gangming Luo ,  Robert S. Siffert ,  William A. Johnson ,  Ronald L. Altman ,  Jonathan J. Kaufman

发明人： Gangming Luo ,  Robert S. Siffert ,  William A. Johnson ,  Ronald L. Altman ,  Jonathan J. Kaufman

IPC分类号： A61B8/00

CPC分类号： A61B8/0875

摘要： A method for the assessment of various properties of bone is provided. The method includes applying a pair of ultrasound transducers to skin on opposite sides of the bone and generating an ultrasound signal and directing the signal through both the bone to obtain a bone output signal. The method further includes establishing a set of parameters associated with the bone output signal and then further processing the parameters in order to obtain the desired bone property. Two novel parameters are also disclosed, namely the net time delay (NTD) and mean time duration (MTD) parameters. An apparatus for the assessment of various properties of bone is also provided. The apparatus includes a pair of ultrasound transducers which may be single-element transducers or array transducers in any combination. The apparatus further includes various computer hardware components and computer software for generating and directing the ultrasound signal, establishing the parameter set and performing the processing. In addition, an apparatus that is battery powered, handheld, and portable and operates in real time is also provided.

摘要翻译： 提供了一种用于评估骨骼各种性质的方法。 该方法包括将一对超声换能器应用于骨的相对侧上的皮肤并产生超声信号并将信号引导通过骨骼以获得骨输出信号。 该方法还包括建立与骨输出信号相关联的一组参数，然后进一步处理参数以获得期望的骨性质。 还公开了两个新颖的参数，即净时延（NTD）和平均持续时间（MTD）参数。 还提供了用于评估骨的各种性质的装置。 该装置包括一对超声换能器，其可以是任何组合的单元件换能器或阵列换能器。 该装置还包括用于生成和指导超声信号的各种计算机硬件组件和计算机软件，建立参数组并执行处理。 此外，还提供了电池供电，手持式和便携式并且实时操作的装置。

公开(公告)号：US07901356B2

公开(公告)日：2011-03-08

申请号：US11954554

申请日：2007-12-12

申请人： Gangming Luo ,  Jonathan J. Kaufman

发明人： Gangming Luo ,  Jonathan J. Kaufman

IPC分类号： A61B8/00

CPC分类号： A61B8/0875

摘要： An invention is disclosed for locating a region of interest in the calcaneus. A pair of ultrasound transducers are positioned on the medial and lateral sides of the heel, respectively. The positioning is based on a size of a portion of the body of a subject upon whom the ultrasound assessment of the calcaneus is to be made. In a presently preferred embodiment, the length of the foot from the back to the head of the first metatarsal is used in conjunction with a proportionality constant and an angle, to position the pair of transducers. The positioning so obtained facilitates (i) reproducible measurements and (ii) comparisons of the results obtained in one person with another, because relatively analogous portions of the highly heterogeneous calcanei are assessed in both. In an alternative embodiment, a single transducer is positioned similarly on the heel, operating in pulse-echo mode.

摘要翻译： 公开了用于在跟骨中定位感兴趣区域的发明。 一对超声波换能器分别位于跟部的内侧和外侧。 定位是基于要对其进行跟骨的超声评估的受试者身体的一部分的大小。 在当前优选的实施例中，从第一跖骨的背部到头部的脚的长度与比例常数和角度一起使用以定位该对换能器。 如此获得的定位有助于（i）可再现的测量和（ii）将在一个人中获得的结果与另一个人的结果进行比较，因为在两者中评估了高度异质的calcanei的相对类似的部分。 在替代实施例中，单个换能器类似地定位在跟部上，以脉冲回波模式操作。

公开(公告)号：US11709547B1

公开(公告)日：2023-07-25

申请号：US17709865

申请日：2022-03-31

申请人： Gangming Luo

发明人： Gangming Luo

IPC分类号： G06F3/01 ,  G06F3/14

CPC分类号： G06F3/14 ,  G06F3/016

摘要： A system for transmitting signals between a body of a living being and a virtual reality space includes a wearable device configured to be worn on the body. The device provides haptic feedback to the body indicative of interactions between a virtual body and one or more virtual objects within the virtual reality space. The device includes a base affixed to the body, a container supported on the base, and a flow control device that controls flow of a mass between the container and a tank. A controller generates a flow control signal to control the flow control device responsive to an interaction between the virtual body and a virtual object within the virtual reality space. The container assumes an expanded state in which the container assumes a defined shape when the mass is present in the container and a contracted state in the absence of the mass.

公开(公告)号：US20180011535A1

公开(公告)日：2018-01-11

申请号：US15203970

申请日：2016-07-07

申请人： Gangming Luo ,  Jonathan J. Kaufman

发明人： Gangming Luo ,  Jonathan J. Kaufman

IPC分类号： G06F3/01

CPC分类号： G06F3/014

摘要： A system for transmitting signals between a body of a living being and a virtual reality space includes a mount and a base configured to be affixed to respective first and second bony members of the body on a distal side and a proximal side, respectively, of a joint. An elongate, flexible strip is affixed at a first end to the mount and at a second end to the base. A sensor disposed on the base is configured to generate a displacement signal indicative of displacement of the strip in response to movement of the first bony member relative to the second bony member. The system further includes a display and a controller configured to receive the displacement signal and to control movement of a virtual representation of the body on the display responsive to the displacement signal and feedback of interaction in the virtual space to the living being.

公开(公告)号：US20120010509A1

公开(公告)日：2012-01-12

申请号：US13177892

申请日：2011-07-07

申请人： Jonathan J. Kaufman ,  Gangming Luo

发明人： Jonathan J. Kaufman ,  Gangming Luo

IPC分类号： A61B8/00

CPC分类号： A61B8/00

摘要： A method and apparatus for non-invasive and quantitative assessment of the status of a lumbar vertebral body in a living being for at least one of several quantities (e.g., bone-mineral density, bone mass, etc.) is provided. The method includes the steps of acoustically coupling first and second transducers to nearby skin on opposite sides of a torso of the living being and generating an ultrasound signal and directing the ultrasound signal from the first transducer to the second transducer through the torso. At least a portion of the ultrasound signal passes through the lumbar vertebral body and the second transducer generates an output signal responsive to receipt of the ultrasound signal. The method further includes the step of processing the output signal to obtain an estimate of the at least one quantity.

摘要翻译： 本发明提供了一种用于非侵入性和定量评估活体中至少一种数量（例如骨 - 矿物质密度，骨量等）的腰椎的身体的方法和装置。 该方法包括以下步骤：将第一和第二换能器耦合到生物体的躯干的相对侧上的附近皮肤，并产生超声信号，并通过躯干将来自第一换能器的超声信号引导到第二换能器。 所述超声信号的至少一部分通过所述腰椎体，并且所述第二换能器响应于所述超声信号的接收而产生输出信号。 该方法还包括处理输出信号以获得至少一个量的估计的步骤。

公开(公告)号：US20110125015A1

公开(公告)日：2011-05-26

申请号：US13015141

申请日：2011-01-27

申请人： Gangming Luo ,  Jonathan J. Kaufman

发明人： Gangming Luo ,  Jonathan J. Kaufman

IPC分类号： A61B8/00

CPC分类号： A61B8/0875

摘要： An invention is disclosed for locating a region of interest in the calcaneus. A pair of ultrasound transducers are positioned on the medial and lateral sides of the heel, respectively. The positioning is based on a size of a portion of the body of a subject upon whom the ultrasound assessment of the calcaneus is to be made. In a presently preferred embodiment, the length of the foot from the back to the head of the first metatarsal is used in conjunction with a proportionality constant and an angle, to position the pair of transducers. The positioning so obtained facilitates (i) reproducible measurements and (ii) comparisons of the results obtained in one person with another, because relatively analogous portions of the highly heterogeneous calcanei are assessed in both. In an alternative embodiment, a single transducer is positioned similarly on the heel, operating in pulse-echo mode.

摘要翻译： 公开了用于在跟骨中定位感兴趣区域的发明。 一对超声波换能器分别位于跟部的内侧和外侧。 定位是基于要对其进行跟骨的超声评估的受试者身体的一部分的大小。 在当前优选的实施例中，从第一跖骨的背部到头部的脚的长度与比例常数和角度一起使用以定位该对换能器。 如此获得的定位有助于（i）可再现的测量和（ii）将在一个人中获得的结果与另一个人的结果进行比较，因为在两者中评估了高度异质的calcanei的相对类似的部分。 在替代实施例中，单个换能器类似地定位在跟部上，以脉冲回波模式操作。