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    Fluid delivery system including a valve and a pressure transducer
    1.
    发明授权
    Fluid delivery system including a valve and a pressure transducer 有权
    流体输送系统包括阀和压力传感器

    公开(公告)号：US08852147B2

    公开(公告)日：2014-10-07

    申请号：US11017324

    申请日：2004-12-20

    申请人： Gerald W. Callan ,  Luis A. Pedraza ,  Jennie Kwo ,  Christopher T. Zirps ,  Roderick H. Beaulieu

    发明人： Gerald W. Callan ,  Luis A. Pedraza ,  Jennie Kwo ,  Christopher T. Zirps ,  Roderick H. Beaulieu

    IPC分类号： A61M37/00 ,  A61M5/145 ,  A61M5/00 ,  A61M31/00 ,  A61M5/14 ,  A61M39/22 ,  A61M5/168

    CPC分类号： A61M5/007 ,  A61M5/14546 ,  A61M5/16827 ,  A61M31/005 ,  A61M39/22 ,  A61M2005/1403 ,  A61M2205/582 ,  A61M2209/01 ,  Y10T137/7727

    摘要： A pressure isolation mechanism for use in a medical procedure includes a lumen, an isolation port in fluid connection with lumen, and a valve having a first state and a second state. The first state occurs when the lumen and the isolation port are connected. The second state occurs when the lumen and the isolation port are disconnected. The lumen remains open for flow of fluid therethrough in the first state and in the second state. The valve is normally in the first state and is switchable to the second state when fluid pressure in the lumen reaches a predetermined pressure level. A pressure transducer can be in fluid connection with the isolation port of the pressure isolation mechanism A fluid delivery system includes a manually operated syringe and a pressure isolation mechanism as described above.

    摘要翻译： 用于医疗过程的压力隔离机构包括内腔，与内腔流体连接的隔离端口以及具有第一状态和第二状态的阀。 当管腔和隔离口连接时，发生第一种状态。 当管腔和隔离端口断开时，发生第二种状态。 在第一状态和第二状态下，内腔保持打开以使流体流过其中。 阀通常处于第一状态，并且当内腔中的流体压力达到预定压力水平时可切换到第二状态。 压力传感器可以与压力隔离机构的隔离端口流体连接。 流体输送系统包括手动操作的注射器和如上所述的压力隔离机构。

    Method and apparatus for fractional flow reserve measurements
    6.
    发明授权
    Method and apparatus for fractional flow reserve measurements 有权
    分数流储备测量的方法和装置

    公开(公告)号：US09314584B1

    公开(公告)日：2016-04-19

    申请号：US13534864

    申请日：2012-06-27

    申请人： Michael A. Riley ,  Michael A. Spohn ,  Gerald W. Callan

    发明人： Michael A. Riley ,  Michael A. Spohn ,  Gerald W. Callan

    IPC分类号： A61M25/00 ,  A61M25/01

    CPC分类号： A61B5/02028 ,  A61B5/02007 ,  A61B5/021 ,  A61B5/02158 ,  A61B5/6852 ,  A61B5/743 ,  A61B5/7475 ,  A61M5/007 ,  A61M25/00 ,  A61M2025/0002 ,  A61M2025/0183

    摘要： A method of determining fractional flow reserve (FFR) in a blood vessel having stenosis includes injecting fluid into the blood vessel upstream of the stenosis using a power fluid injector, measuring pressure drop across the stenosis, and calculating FFR from measured pressure drop. The injected fluid may comprise a contrast medium. Further actions may include placing a pressure sensor proximal of the stenosis, injecting fluid into the blood vessel upstream of the stenosis using the power fluid injector, and measuring pressure in the blood vessel proximal of the stenosis. The pressure sensor may then be repositioned to a position distal of the stenosis, fluid may be reinjected into the blood vessel upstream of the stenosis using the power fluid injector, and pressure may be measured in the blood vessel distal of the stenosis.

    摘要翻译： 在具有狭窄的血管中确定分数流量储备（FFR）的方法包括使用动力流体注射器将流体注入到狭窄上游的血管中，测量狭窄处的压降，以及从测量的压降计算FFR。 注入的流体可以包括造影剂。 进一步的动作可以包括将压力传感器放置在狭窄附近，使用动力流体注射器将流体注入狭窄的上游的血管，以及测量狭窄近端的血管中的压力。 压力传感器然后可以重新定位到狭窄远端的位置，流体可以使用动力流体注射器在狭窄的上游再注入到血管中，并且可以在狭窄远端的血管中测量压力。

    Fluid delivery system having pump systems, check valves and a removable patient interface
    8.
    发明授权
    Fluid delivery system having pump systems, check valves and a removable patient interface 有权
    流体输送系统具有泵系统，止回阀和可移除的患者接口

    公开(公告)号：US06972001B2

    公开(公告)日：2005-12-06

    申请号：US10790299

    申请日：2004-03-01

    申请人： Michael F. Emig ,  Klaus Urich ,  Frederick Trombley, III ,  Joseph B. Havrilla ,  Edward J. Rhinehart ,  Gerald W. Callan

    发明人： Michael F. Emig ,  Klaus Urich ,  Frederick Trombley, III ,  Joseph B. Havrilla ,  Edward J. Rhinehart ,  Gerald W. Callan

    IPC分类号： A61M5/00 ,  A61M5/14 ,  A61M5/168 ,  A61M39/26 ,  A61M37/00

    CPC分类号： A61M5/1407 ,  A61M5/007 ,  A61M5/16827 ,  A61M39/26 ,  Y10S128/01

    摘要： A fluid delivery system for delivery of an injection fluid to a patient generally includes a first pump system, a second pump system, a patient interface in removable fluid connection with the first and second pump systems, and a fluid path in fluid connection between the first and second pump systems and the patient interface. The fluid path preferably includes a housing member defining a first inlet, a second inlet and an outlet. The first and second pump systems are placed in fluid connection with the respective first and second inlets of the housing member and the patient interface is placed in removable fluid connection with the outlet of the housing member. A first check valve is in fluid connection between an outlet of the first pump system and the first inlet of the housing member, and a second check valve is in fluid connection between an outlet of the second pump system and the second inlet of the housing member.

    摘要翻译： 用于将注射流体输送到患者的流体递送系统通常包括第一泵系统，第二泵系统，与第一和第二泵系统可移动流体连接的患者接口，以及在第一和第二泵系统之间流体连接的流体路径 和第二泵系统和患者接口。 流体路径优选地包括限定第一入口，第二入口和出口的壳体构件。 第一和第二泵系统被放置成与壳体构件的相应的第一和第二入口流体连接，并且患者接口被放置成与壳体构件的出口可移动的流体连接。 第一止回阀在第一泵系统的出口和壳体构件的第一入口之间流体连接，并且第二止回阀在第二泵系统的出口和壳体构件的第二入口之间流体连接 。

    Agglutination detection apparatus
    9.
    发明授权
    Agglutination detection apparatus 失效
    凝集检测装置

    公开(公告)号：US5256376A

    公开(公告)日：1993-10-26

    申请号：US758772

    申请日：1991-09-12

    申请人： Gerald W. Callan ,  William D. Corry ,  Richard E. Scordato ,  John G. Gorman

    发明人： Gerald W. Callan ,  William D. Corry ,  Richard E. Scordato ,  John G. Gorman

    IPC分类号： G01N21/07 ,  G02N21/05

    CPC分类号： G01N21/07 ,  Y10S436/809

    摘要： A method and apparatus are provided for use with a centrifuge to analyze reactants. The apparatus includes at least one cuvette having at least one chamber. The chamber has a radially outward wall which provides a base upon which reactants can be pelleted when the device is rotated about a centrifugal axis. Each cuvette includes one or more openings for introducing fluids to the cuvette and includes a channel positioned adjacent to the radially outward wall for removing fluids from the chamber. Pressure is applied to the chamber to force fluids therefrom, through the channel. A hold down device is also provided through which fluid and/or pressure may be passed with respect to the cuvette. The invention also provides a method for determining the existence and degree of agglutination of reactants in a first fluid suspension and contained in a single reaction vessel using a photodetector.

    摘要翻译： 提供了一种与离心机一起使用以分析反应物的方法和装置。 该装置包括至少一个具有至少一个室的试管。 该室具有径向向外的壁，其提供基部，当该装置围绕离心轴线旋转时，反应物可在该基底上沉淀。 每个比色皿包括用于将流体引入比色杯的一个或多个开口，并且包括邻近径向向外的壁定位的通道，用于从腔室去除流体。 压力被施加到室以通过通道迫使流体。 还提供了压缩装置，流体和/或压力可以相对于比色杯通过。 本发明还提供了一种用于确定第一流体悬浮液中反应物的凝集存在和程度的方法，并且使用光电检测器包含在单个反应容器中。