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公开(公告)号:US08796275B2
公开(公告)日:2014-08-05
申请号:US12510593
申请日:2009-07-28
申请人: Richard W. Scott , Doron Greenbaum , Dahui Liu , Xiaodong Fan , Yongjiang Xu , Haizhong Tang , Ehab Khalil
发明人: Richard W. Scott , Doron Greenbaum , Dahui Liu , Xiaodong Fan , Yongjiang Xu , Haizhong Tang , Ehab Khalil
IPC分类号: C07D241/04 , C07D209/58 , C07D307/91 , C07D333/76 , A61K31/381
CPC分类号: C07D239/28 , C07C217/90 , C07C317/22 , C07C323/42 , C07C323/44 , C07D207/12 , C07D295/096 , C07D295/135 , C07D333/76 , C07D335/12
摘要: The present invention provides tricyclic compounds, arylamide compounds, and other compounds, and compositions comprising the same, for treating malaria, and methods of treating malaria comprising administering such compounds to an animal.
摘要翻译: 本发明提供了三环化合物,芳酰胺化合物和其它化合物及其组合物,包含其的用于治疗疟疾的组合物,以及治疗疟疾的方法,包括向动物施用此类化合物。
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公开(公告)号:US08278309B2
公开(公告)日:2012-10-02
申请号:US12605584
申请日:2009-10-26
申请人: William F. DeGrado , Dahui Liu , Richard W. Scott , Yongjiang Xu , Haizhong Tang , Bozena Korczak
发明人: William F. DeGrado , Dahui Liu , Richard W. Scott , Yongjiang Xu , Haizhong Tang , Bozena Korczak
IPC分类号: A01N43/54 , C07D239/02
CPC分类号: C07D403/14
摘要: The present invention provides arylamide compounds and methods of making and using them as antibiotics.
摘要翻译: 本发明提供芳基酰胺化合物及其制备和使用它们作为抗生素的方法。
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3.Compounds And Methods For Treating Candidiasis And Aspergillus Infections 有权
标题翻译: 化合物和治疗念珠菌和曲霉菌感染的方法公开(公告)号:US20130252964A1
公开(公告)日:2013-09-26
申请号:US13744517
申请日:2013-01-18
申请人: Richard W. Scott , Katie Freeman , Haizhong Tang , Gill Diamond
发明人: Richard W. Scott , Katie Freeman , Haizhong Tang , Gill Diamond
IPC分类号: C07D409/14 , C07D209/86 , C07D249/06 , C07D239/26 , C07C237/08 , C07C279/12 , C07C211/27 , C07C211/28 , C07C279/08 , C07C217/20 , C07D333/20 , C07D307/52 , C07D277/28 , C07D239/38 , C07D333/76 , C07D307/91 , C07D239/28
CPC分类号: A61K31/506 , A01N25/00 , A61K9/0053 , A61K9/06 , A61K31/381 , A61K31/404 , A61K31/4192 , A61K31/4436 , A61K31/496 , A61K31/505 , C07C211/27 , C07C211/28 , C07C211/29 , C07C217/20 , C07C237/08 , C07C279/04 , C07C279/06 , C07C279/08 , C07C279/12 , C07D209/86 , C07D239/26 , C07D239/28 , C07D239/38 , C07D249/06 , C07D277/28 , C07D307/52 , C07D307/91 , C07D333/20 , C07D333/76 , C07D409/14
摘要: The present disclosure provides compounds, or pharmaceutically acceptable salts thereof, for killing or inhibiting the growth of a Candida or Aspergillus species or preventing or treating a mammal having candidiasis (oral and/or disseminated) or an Aspergillus infection.
摘要翻译: 本公开内容提供了用于杀死或抑制念珠菌或曲霉菌种的生长或预防或治疗具有念珠菌病(口服和/或播撒)或曲霉属感染的哺乳动物的化合物或其药学上可接受的盐。
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公开(公告)号:US20100105703A1
公开(公告)日:2010-04-29
申请号:US12605584
申请日:2009-10-26
申请人: William F. DeGrado , Dahui Liu , Richard W. Scott , Yongjiang Xu , Haizhong Tang , Bozena Korczak
发明人: William F. DeGrado , Dahui Liu , Richard W. Scott , Yongjiang Xu , Haizhong Tang , Bozena Korczak
IPC分类号: A61K31/506 , C07D403/14 , A61P31/04
CPC分类号: C07D403/14
摘要: The present invention provides arylamide compounds and methods of making and using them as antibiotics.
摘要翻译: 本发明提供芳基酰胺化合物及其制备和使用它们作为抗生素的方法。
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公开(公告)号:US20100081665A1
公开(公告)日:2010-04-01
申请号:US12510593
申请日:2009-07-28
申请人: Richard W. Scott , Doron Greenbaum , Dahui Liu , Xiaodong Fan , Yongjiang Xu , Haizhong Tang , Ehab Khalil
发明人: Richard W. Scott , Doron Greenbaum , Dahui Liu , Xiaodong Fan , Yongjiang Xu , Haizhong Tang , Ehab Khalil
IPC分类号: A61K31/496 , C07C237/14 , A61K31/167 , C07D403/12 , A61K31/495 , C07D239/26 , A61P33/06
CPC分类号: C07D239/28 , C07C217/90 , C07C317/22 , C07C323/42 , C07C323/44 , C07D207/12 , C07D295/096 , C07D295/135 , C07D333/76 , C07D335/12
摘要: The present invention provides tricyclic compounds, arylamide compounds, and other compounds, and compositions comprising the same, for treating malaria, and methods of treating malaria comprising administering such compounds to an animal.
摘要翻译: 本发明提供了三环化合物,芳酰胺化合物和其它化合物及其组合物,包含其的用于治疗疟疾的组合物,以及治疗疟疾的方法,包括向动物施用此类化合物。
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公开(公告)号:US08975262B2
公开(公告)日:2015-03-10
申请号:US13563928
申请日:2012-08-01
申请人: William F. DeGrado , Haizhong Tang , Bozena Korczak , Dahui Liu , Richard W. Scott , Yongjiang Xu
发明人: William F. DeGrado , Haizhong Tang , Bozena Korczak , Dahui Liu , Richard W. Scott , Yongjiang Xu
IPC分类号: C07D403/14
CPC分类号: C07D403/14
摘要: The present invention provides arylamide compounds and methods of making and using them as antibiotics.
摘要翻译: 本发明提供芳基酰胺化合物及其制备和使用它们作为抗生素的方法。
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公开(公告)号:US20130274502A1
公开(公告)日:2013-10-17
申请号:US13720298
申请日:2012-12-19
申请人: Robert W. Kavash , Haizhong Tang , Carol Mulrooney , Dahui Liu
发明人: Robert W. Kavash , Haizhong Tang , Carol Mulrooney , Dahui Liu
IPC分类号: C07C231/14 , C07C271/52 , C07C231/12
CPC分类号: C07C231/12 , C07C231/02 , C07C231/10 , C07C231/14 , C07C235/12 , C07C237/34 , C07C271/22 , C07C271/52 , C07C237/44
摘要: The present invention provides methods for preparing a polymeric compound of Formula I: or pharmaceutically acceptable salt thereof. The present invention also provides useful intermediates for preparing the compound of Formula I or pharmaceutically acceptable salt thereof.
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公开(公告)号:US20130090345A1
公开(公告)日:2013-04-11
申请号:US13563928
申请日:2012-08-01
申请人: Willam F. DeGrado , Haizhong Tang , Bozena Korczak , Dahui Liu , Richard W. Scott , Yongjiang Xu
发明人: Willam F. DeGrado , Haizhong Tang , Bozena Korczak , Dahui Liu , Richard W. Scott , Yongjiang Xu
IPC分类号: C07D403/14
CPC分类号: C07D403/14
摘要: The present invention provides arylamide compounds and methods of making and using them as antibiotics.
摘要翻译: 本发明提供芳基酰胺化合物及其制备和使用它们作为抗生素的方法。
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公开(公告)号:US08354556B2
公开(公告)日:2013-01-15
申请号:US12908977
申请日:2010-10-21
申请人: Robert W. Kavash , Haizhong Tang , Carol Mulrooney , Dahui Liu
发明人: Robert W. Kavash , Haizhong Tang , Carol Mulrooney , Dahui Liu
IPC分类号: C07C233/65 , C07C229/44
CPC分类号: C07C231/12 , C07C231/02 , C07C231/10 , C07C231/14 , C07C235/12 , C07C237/34 , C07C271/22 , C07C271/52 , C07C237/44
摘要: The present invention provides methods for preparing a polymeric compound of Formula I: or pharmaceutically acceptable salt thereof. The present invention also provides useful intermediates for preparing the compound of Formula I or pharmaceutically acceptable salt thereof.
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10.Facially Amphiphilic Compounds, Compositions, And Uses Thereof In Treating Cancer 审中-公开
标题翻译: 表面两性化合物,组合物及其用途在治疗癌症公开(公告)号:US20120115877A1
公开(公告)日:2012-05-10
申请号:US13214177
申请日:2011-08-20
申请人: Richard W. Scott , Dylan Clements , Yongjiang Xu , Haizhong Tang , Carol Mulrooney , Ehab Khalil , Damian Weaver , Xiaodong Fan
发明人: Richard W. Scott , Dylan Clements , Yongjiang Xu , Haizhong Tang , Carol Mulrooney , Ehab Khalil , Damian Weaver , Xiaodong Fan
IPC分类号: A61K31/496 , A61K31/4025 , A61P35/00 , A61K31/343 , A61P35/02 , A61K31/505 , A61K31/381
摘要: The present invention discloses compositions of facially amphiphilic compounds and their use in methods for treating or reducing cancers in animals, such as humans.
摘要翻译: 本发明公开了表面两亲化合物的组合物及其用于治疗或减少动物如人类的癌症的方法。
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