-
公开(公告)号:US20080299125A1
公开(公告)日:2008-12-04
申请号:US11810694
申请日:2007-06-05
申请人: David A. Hinds , David R. Cox , Craig L. Hyde , Hakan Sakul
发明人: David A. Hinds , David R. Cox , Craig L. Hyde , Hakan Sakul
IPC分类号: C12Q1/68 , A61K39/395 , A61K38/16 , A01K67/027 , A61P25/24 , A61K31/7088 , G01N33/53
CPC分类号: C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158
摘要: The invention provides a collection of polymorphic sites associated with response to treatment by an SSRI or placebo in depression patients. The polymorphic sites and others in linkage disequilibrium with them are useful in determining whether to treat a patient with an SSRI or include a patient in a clinical trial to test an SSRI.
摘要翻译: 本发明提供了与抑郁症患者中SSRI或安慰剂治疗反应相关的多态性位点的集合。 与它们连锁不平衡的多态性位点和其他位点可用于确定是否用SSRI治疗患者或在临床试验中包括患者以测试SSRI。