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公开(公告)号:US07767236B2
公开(公告)日:2010-08-03
申请号:US11400188
申请日:2006-04-10
申请人: Naoto Koyama , Tetsuya Seki , Harumi Arisaka , Koichi Ishii
发明人: Naoto Koyama , Tetsuya Seki , Harumi Arisaka , Koichi Ishii
IPC分类号: A61K36/286
CPC分类号: A61K31/7056 , A23L33/105 , A61K31/4045 , A61K31/7048 , A61K36/286 , A61K36/31 , A61K36/48
摘要: Plant seed extract compositions obtained by washing a defatted plant seed with water, and extracting the resulting washed seed product with an organic solvent and safflower seed extract compositions wherein the weight ratio of the total content of (a) p-coumaroylserotonin, feruloylserotonin, p-coumaroylserotonin glycoside, and feruloylserotonin glycoside to (b) 2-hydroxyarctiin is 1:0.01 to 0.2, are effective for reducing the risk of developing atherosclerosis and diseases caused by atherosclerosis and also exhibit a reduced tendency to cause diarrhea.
摘要翻译: 通过用水洗涤脱脂植物种子获得的植物种子提取物组合物,并用有机溶剂和红花种子提取物组合物萃取所得洗涤的种子产物,其中(a)对 - 香豆酰维持血清素,阿魏酰血清素,对 - (b)2-羟基肌动蛋白为1:0.01〜0.2,对于降低发生动脉粥样硬化和动脉粥样硬化引起的疾病的风险有效,并且也呈现降低的引起腹泻的倾向。
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公开(公告)号:US20060257540A1
公开(公告)日:2006-11-16
申请号:US11400188
申请日:2006-04-10
申请人: Naoto Koyama , Tetsuya Seki , Harumi Arisaka , Koichi Ishii
发明人: Naoto Koyama , Tetsuya Seki , Harumi Arisaka , Koichi Ishii
IPC分类号: A23L2/02
CPC分类号: A61K31/7056 , A23L33/105 , A61K31/4045 , A61K31/7048 , A61K36/286 , A61K36/31 , A61K36/48
摘要: Plant seed extract compositions obtained by washing a defatted plant seed with water, and extracting the resulting washed seed product with an organic solvent and safflower seed extract compositions wherein the weight ratio of the total content of (a) p-coumaroylserotonin, feruloylserotonin, p-coumaroylserotonin glycoside, and feruloylserotonin glycoside to (b) 2-hydroxyarctiin is 1:0.01 to 0.2, are effective for reducing the risk of developing atherosclerosis and diseases caused by atherosclerosis and also exhibit a reduced tendency to cause diarrhea.
摘要翻译: 通过用水洗涤脱脂植物种子获得的植物种子提取物组合物,并用有机溶剂和红花种子提取物组合物萃取所得洗涤的种子产物,其中(a)对 - 香豆酰维持血清素,阿魏酰血清素,对 - (b)2-羟基肌动蛋白为1:0.01〜0.2,对于降低发生动脉粥样硬化和动脉粥样硬化引起的疾病的风险有效,并且也呈现降低的引起腹泻的倾向。
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3.
公开(公告)号:US5932593A
公开(公告)日:1999-08-03
申请号:US917180
申请日:1997-08-25
IPC分类号: A61K31/4427 , A61K31/4433 , A61K31/444 , A61K31/4465 , A61K31/451 , A61K31/4535 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61K31/541 , A61P3/10 , A61P7/00 , A61P7/02 , A61P9/00 , A61P9/06 , A61P9/08 , A61P9/10 , A61P9/12 , A61P13/12 , A61P17/00 , A61P17/02 , A61P43/00 , C07D211/70 , C07D401/12 , C07D409/04 , C07D409/14 , A61K31/445
CPC分类号: A61K31/541 , A61K31/444 , A61K31/451 , A61K31/4535 , A61K31/4545 , A61K31/496 , A61K31/5377 , C07D211/70 , C07D401/12 , C07D409/04 , C07D409/14
摘要: The present invention also relates to a method of using these novel materials, and other materials, to treat or prevent a disease caused by serotonin or a method of treating or preventing platelet aggregation. The compounds used are piperidine derivatives having the formula (I): ##STR1## wherein the various substituents are defined below.
摘要翻译: 本发明还涉及使用这些新型材料和其他材料来治疗或预防5-羟色胺引起的疾病的方法或治疗或预防血小板聚集的方法。 所用的化合物是具有式(I)的哌啶衍生物:其中各种取代基如下定义。
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