Anticholinergics, processes for preparing them and pharmaceutical composition containing them
    1.
    发明授权
    Anticholinergics, processes for preparing them and pharmaceutical composition containing them 有权
    抗胆碱能药,其制备方法和含有它们的药物组合物

    公开(公告)号:US07652138B2

    公开(公告)日:2010-01-26

    申请号:US10970240

    申请日:2004-10-21

    IPC分类号: C07D491/00 C07D451/00

    CPC分类号: C07D451/10 C07D451/14

    摘要: A compound of formula 1 wherein: A is a group selected from X− is an anion with a single negative charge; R1 and R2 are each independently a C1-C4-alkyl optionally substituted with hydroxy or halogen; and R3, R4, R5, R6, R7, and R8 are each independently hydrogen, C1-C4-alkyl, C1-C4-alkyloxy, hydroxy, CF3, CN, NO2, or halogen, with the proviso that at least one of the groups R3, R4, R5, R6, R7, and R8 is not hydrogen, processes for preparing these compounds, pharmaceutical compositions containing these compounds, and their use as pharmaceutical compositions.

    摘要翻译: 式1的化合物,其中:A是选自X - 是具有单个负电荷的阴离子; R 1和R 2各自独立地为任选被羟基或卤素取代的C 1 -C 4烷基; 并且R 3,R 4,R 5,R 6,R 7和R 8各自独立地为氢,C 1 -C 4 - 烷基,C 1 -C 4 - 烷氧基,羟基,CF 3,CN,NO 2或卤素,条件是至少一个 R 3,R 4,R 5,R 6,R 7和R 8不是氢,制备这些化合物的方法,含有这些化合物的药物组合物及其作为药物组合物的用途。

    Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions
    3.
    发明授权
    Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions 有权
    呫吨羧酸盐,其制备方法及其作为药物组合物的用途

    公开(公告)号:US07405224B2

    公开(公告)日:2008-07-29

    申请号:US10342080

    申请日:2003-01-14

    IPC分类号: A61K31/44

    CPC分类号: C07D451/06 C07D451/10

    摘要: Xanthenecarboxylates of formula 1 wherein: A is a group selected from X− is an anion with a single negative charge; R is hydroxy, methyl, hydroxymethyl, ethyl, —CF3, —CHF2, or fluorine; R1 and R2, which are identical or different, are each C1-C5-alkyl which is optionally substituted by C3-C6-cycloalkyl, hydroxy, or halogen, or R1 and R2 together denote a —C3-C5-alkylene-bridge; and R3, R4, R3′, and R4′, which are identical or different, are each hydrogen, —C1-C4-alkyl, —C4-alkyloxy, hydroxy, —CF3, —CHF2, —CN, —NO2, or halogen, or a physiologically acceptable salt thereof, processes for preparing, them and their use in pharmaceutical compositions.

    摘要翻译: 式1的呫吨羧酸盐其中:A是选自X - 的一个基团,是具有单个负电荷的阴离子; R是羟基,甲基,羟甲基,乙基,-CF 3,-CHF 2,或氟; R 1和R 2相同或不同,分别为C 1 -C 5 - 烷基,其中R 1和R 2各自为C 1 -C 5 - 任选被C 3 -C 6 - 环烷基,羟基或卤素取代,或R 1和R 2 - >一起表示-C 3 -C 5 - 亚烷基桥; 和R 3,R 4,R 3,R 3和R 4'相同或不同, 各自为氢,-C 1 -C 4 - 烷基,-C 4 - 烷氧基,羟基,-CF 3 - 或其生理学上可接受的盐,其制备方法,它们及其在药物组合物中的用途。

    Electronic microscope
    8.
    发明申请
    Electronic microscope 有权
    电子显微镜

    公开(公告)号:US20070121204A1

    公开(公告)日:2007-05-31

    申请号:US10546020

    申请日:2004-02-18

    IPC分类号: G02B21/06

    CPC分类号: G02B21/0008 G02B21/361

    摘要: The invention relates to a microscope having an optics system which represents an object on an image sensor and a screen that shows the image data provided by the image sensor and which is the only output medium for visually observing the object, wherein the representation capability of the optics system and the resolution (A) of the image sensor complies with the following correlation: F×N/M=0.5 A, wherein F indicates a factor, N indicates the numerical aperture of the optics systems, M is the magnification factor and A indicates the resolution of the image sensor in pixels per millimeter.

    摘要翻译: 本发明涉及具有表示图像传感器上的物体的光学系统和显示由图像传感器提供的图像数据并且是用于目视观察物体的唯一输出介质的屏幕的显微镜,其中, 光学系统和图像传感器的分辨率(A)符合以下相关:FxN / M = 0.5A,其中F表示因子,N表示光学系统的数值孔径,M表示放大系数,A表示 图像传感器的分辨率为每毫米像素。