中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

37 records (took 0.019 seconds)

    CHARACTERIZATION OF BLOOD HEMOSTASIS AND OXYGEN TRANSPORT PARAMETERS
    1.
    发明申请
    CHARACTERIZATION OF BLOOD HEMOSTASIS AND OXYGEN TRANSPORT PARAMETERS 有权

    公开(公告)号：US20210148889A1

    公开(公告)日：2021-05-20

    申请号：US17106307

    申请日：2020-11-30

    Applicant: HemoSonics LLC

    Inventor： Francesco Viola ,  William F. Walker

    IPC: G01N33/49 ,  G01N29/024 ,  G01N29/032 ,  G01N29/028 ,  G01N29/44

    Abstract: An integrated system for determining a hemostasis and oxygen transport parameter of a blood sample, such as blood, is disclosed. The system includes a measurement system, such as an ultrasonic sensor, configured to determine data characterizing the blood sample. For example, the data could be displacement of the blood sample in response to ultrasonic pulses. An integrated aspect of the system may be a common sensor, sample portion or data for fast and efficient determination of both parameters. The parameters can also be used to correct or improve measured parameters. For example, physiological adjustments may be applied to the hemostatic parameters using a HCT measurement. Also, physical adjustments may be applied, such as through calibration using a speed or attenuation of the sound pulse through or by the blood sample. These parameters may be displayed on a GUI to guide treatment.

    Determining mechanical properties via ultrasound-induced resonance
    2.
    发明授权
    Determining mechanical properties via ultrasound-induced resonance 有权

    公开(公告)号：US11002712B2

    公开(公告)日：2021-05-11

    申请号：US16656492

    申请日：2019-10-17

    Applicant: HEMOSONICS LLC

    Inventor： William F. Walker ,  F. Scott Corey ,  Andrew Homyk ,  Tim Higgins ,  Francesco Viola ,  Frank Regan ,  Elisa Ferrante

    IPC: G01N29/44 ,  G01N29/036 ,  A61B8/08 ,  G01N29/22

    Abstract: A device for estimating a mechanical property of a sample is disclosed herein. The device may include a chamber configured to hold the sample; a transmitter configured to transmit a plurality of waveforms, including at least one forcing waveform; and a transducer assembly operatively connected to the transmitter and configured to transform the transmit waveforms into ultrasound waveforms. The transducer assembly can also transmit and receive ultrasound waveforms into and out of the chamber, as well as transform at least two received ultrasound waveforms into received electrical waveforms. The device also includes a data processor that can receive the received electrical waveforms; estimate a difference in the received electrical waveforms that results at least partially from movement of the sample; and estimate a mechanical property of the sample by comparing at least one feature of the estimated difference to at least one predicted feature, wherein the at least one predicted feature is based on a model of an effect of the chamber wall. Finally, the device can also include a controller configured to control the timing of the ultrasound transmitter and data processor.

    Method and apparatus for characterization of clot formation
    5.
    发明授权
    Method and apparatus for characterization of clot formation 有权

    公开(公告)号：US09723996B2

    公开(公告)日：2017-08-08

    申请号：US13791915

    申请日：2013-03-09

    Applicant: HEMOSONICS, LLC

    Inventor： William F. Walker ,  Michael B. Lawrence ,  Francesco Viola ,  Margaret Kramer Sande

    IPC: A61B5/00 ,  A61B5/02 ,  A61B8/08 ,  G01N29/11 ,  G01N29/34

    CPC classification number: A61B5/02028 ,  A61B5/0048 ,  A61B8/08 ,  A61B8/485 ,  G01N29/11 ,  G01N29/343 ,  G01N2291/02466 ,  G01N2291/02475 ,  G01N2291/02827 ,  G01N2291/044

    Abstract: Methods, apparatus and systems for characterizing changes in at least one physical property of soft tissue. A series of acoustic pulses is generated and directed into the soft tissue such that at least one of the pulses is of sufficiently high intensity to induce physical displacement of the tissue. Waves reflected off the tissue, or a flexible member that moves with the tissue, are received and measured to estimate at least one characteristic of the physical displacement induced thereby. Repetition of the generating, receiving and estimating steps provides characterization of the at least one physical property over time. Methods, apparatus and systems for characterizing at least one physical property of blood, by generating a series of acoustic pulses and directing the series of pulses into the blood such that at least one of the pulses is of sufficiently high intensity to induce physical displacement of the blood. Acoustic pulses and/or optical waves reflected from the blood, or a flexible member in contact with the blood that moves with the blood, are received and measured to estimate at least one characteristic of the physical displacement induced thereby.

    DETERMINING MECHANICAL PROPERTIES VIA ULTRASOUND-INDUCED RESONANCE
    8.
    发明申请
    DETERMINING MECHANICAL PROPERTIES VIA ULTRASOUND-INDUCED RESONANCE 有权

    公开(公告)号：US20210199622A1

    公开(公告)日：2021-07-01

    申请号：US17185516

    申请日：2021-02-25

    Applicant: HEMOSONICS LLC

    Inventor： William F. Walker ,  F. Scott Corey ,  Andrew Homyk ,  Tim Higgins ,  Francesco Viola ,  Frank Regan ,  Elisa Ferrante

    IPC: G01N29/44 ,  G01N29/036 ,  A61B8/08 ,  G01N29/22

    Abstract: A device for estimating a mechanical property of a sample is disclosed herein. The device may include a chamber configured to hold the sample; a transmitter configured to transmit a plurality of waveforms, including at least one forcing waveform; and a transducer assembly operatively connected to the transmitter and configured to transform the transmit waveforms into ultrasound waveforms. The transducer assembly can also transmit and receive ultrasound waveforms into and out of the chamber, as well as transform at least two received ultrasound waveforms into received electrical waveforms. The device also includes a data processor that can receive the received electrical waveforms; estimate a difference in the received electrical waveforms that results at least partially from movement of the sample; and estimate a mechanical property of the sample by comparing at least one feature of the estimated difference to at least one predicted feature, wherein the at least one predicted feature is based on a model of an effect of the chamber wall. Finally, the device can also include a controller configured to control the timing of the ultrasound transmitter and data processor.

Patent Agency Ranking