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公开(公告)号：US20140110622A1
公开(公告)日：2014-04-24
申请号：US13809426
申请日：2011-07-11
发明人： Werner Jenninger , Joachim Wagner , Berit Krauter , Stefanie Eiden , Deliani Lovera-Prieto , Holger Egger
IPC分类号： H01L41/193
CPC分类号： H01L41/193 , C08K9/04 , C08L69/00
摘要： The present invention relates to a polymer material comprising a polymer and an organically modified layered silicate dispersed in the polymer. The total content of alkali and/or alkaline earth metal cations in the polymer material is ≦1 ppm. It relates further to the use of the polymer material as an electret material, and to an electromechanical converter comprising such a polymer material.
摘要翻译： 本发明涉及包含分散在聚合物中的聚合物和有机改性层状硅酸盐的聚合物材料。 聚合物材料中碱金属和/或碱土金属阳离子的总含量为1ppm。 它进一步涉及聚合物材料作为驻极体材料的应用，以及包含这种聚合物材料的机电转换器。
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2.发明申请SYSTEM COMPRISING BACTERIOPHAGES AND PARTICLES THAT CONTAIN ACTIVE SUBSTANCES 审中-公开包含活性物质的杀菌剂和颗粒物的系统公开(公告)号：US20130178390A1
公开(公告)日：2013-07-11
申请号：US13744682
申请日：2013-01-18
申请人： STEFANIE EIDEN, I , AXEL EBLE , MARTIN WEISS , DANIEL GORDON DUFF , OLAF BORK , HOLGER EGGER , BASTIAN BUDDE , SASCHA PLUG
发明人： STEFANIE EIDEN, I , AXEL EBLE , MARTIN WEISS , DANIEL GORDON DUFF , OLAF BORK , HOLGER EGGER , BASTIAN BUDDE , SASCHA PLUG
IPC分类号： A61K35/76
CPC分类号： A61K35/76 , A61K47/6901 , C07K7/06 , C07K7/08 , C07K14/005 , C07K17/02 , C07K17/14 , C07K2319/01 , C12N7/00 , C12N15/1037 , C12N2795/14122 , Y10T442/2508 , Y10T442/2525
摘要： The present invention concerns a system, comprising bacteriophages and particles comprising active agents, in which a first additional peptide is fused to proteins of the bacteriophage, the first additional peptide adheres to the surface of the particle and furthermore a second additional peptide is fused to proteins of the bacteriophage. The second additional peptide can adhere on substrate surfaces. The present invention furthermore concerns the use of the system for delayed release of active agents and also a method for production of the system. The present invention furthermore concerns a method for the selection of phage species from a combinatorial phage population.
摘要翻译： 本发明涉及包含噬菌体和包含活性剂的颗粒的系统，其中第一附加肽与噬菌体的蛋白质融合，第一附加肽粘附到颗粒的表面，此外，第二附加肽与蛋白质融合 的噬菌体。 第二个额外的肽可以粘附在基底表面上。 本发明还涉及该系统用于活性剂的延迟释放的用途以及该系统的生产方法。 本发明还涉及从组合噬菌体群体中选择噬菌体物种的方法。
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公开(公告)号：US20120164204A1
公开(公告)日：2012-06-28
申请号：US13392938
申请日：2010-09-10
申请人： Holger Egger , Dirk Storch
发明人： Holger Egger , Dirk Storch
CPC分类号： A61K31/275 , A61K9/5026
摘要： Method for producing stable capsules which comprises the steps of providing a first component comprising a wax-like substance and a second component comprising a substance to be encapsulated, dissolved or dispersed in a liquid medium, homogeneously mixing the first and second components, dispersing the mixture in an aqueous solution using at least one dispersion auxiliary at a temperature above the melting point of the wax-like substance to prepare a microemusion, and cooling and diluting the microemulsion.
摘要翻译： 制备稳定胶囊的方法，包括以下步骤：提供包含蜡状物质的第一组分和第二组分，所述第二组分包含被包封的物质，溶解或分散在液体介质中，均匀混合第一和第二组分，分散混合物 在使用至少一种分散助剂的水溶液中，在高于蜡状物质的熔点的温度下制备微滴，并冷却和稀释微乳液。
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4.发明申请公开(公告)号：US20130197137A1
公开(公告)日：2013-08-01
申请号：US13809126
申请日：2011-07-08
申请人： Jochen Norwig , Ralf Spiale , Wolfgang Assmuth , Holger Egger
发明人： Jochen Norwig , Ralf Spiale , Wolfgang Assmuth , Holger Egger
IPC分类号： C08K5/544
CPC分类号： C08K5/544 , C01B33/44 , Y02P20/542
摘要： The present invention relates to a novel process for preparing organically modified sheet silicates in high purity. The process of the invention uses ion exchange resins for this purpose.
摘要翻译： 本发明涉及一种制备高纯度有机改性片状硅酸盐的新方法。 本发明的方法为此目的使用离子交换树脂。
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5.发明申请COMPOSITION FOR TREATING CANCER BY THE CONTROLLED RELEASE OF AN ACTIVE SUBSTANCE 审中-公开通过控制释放活性物质治疗癌症的组合物公开(公告)号：US20130266637A1
公开(公告)日：2013-10-10
申请号：US13878801
申请日：2011-10-11
申请人： Holger Egger , Bastian Budde , Kai Termming , Anna Arbuzova , Andrea Gramatica , Andreas Herrmann , Juergen Liebscher , Nicolai Brodersen
发明人： Holger Egger , Bastian Budde , Kai Termming , Anna Arbuzova , Andrea Gramatica , Andreas Herrmann , Juergen Liebscher , Nicolai Brodersen
IPC分类号： A61K47/22
CPC分类号： A61K47/22 , A61K31/704 , A61K47/543 , A61K47/551 , A61K47/6911 , A61K47/6913
摘要： The invention relates to a novel composition for treating cancer, which allows the active substance to be released in the direct presence of the cells which are to be treated with the active substance. Said composition comprises an active substance carrier which is in the form of a liposome comprising a disulfide group, a cytostatic agent being contained in the active substance carrier. The invention also relates to a method for the locally defined release of a cytostatic agent.
摘要翻译： 本发明涉及一种用于治疗癌症的新型组合物，其允许活性物质在待用活性物质治疗的细胞的直接存在下释放。 所述组合物包含活性物质载体，其为包含二硫键的脂质体形式，细胞生长抑制剂包含在活性物质载体中。 本发明还涉及局部限定性释放细胞生长抑制剂的方法。
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6.发明授权公开(公告)号：US08399236B2
公开(公告)日：2013-03-19
申请号：US12672096
申请日：2008-08-01
申请人： Stefanie Eiden , Axel Eble , Martin Weiss , Daniel Gordon Duff , Olaf Bork , Holger Egger , Bastian Budde , Sascha Plug
发明人： Stefanie Eiden , Axel Eble , Martin Weiss , Daniel Gordon Duff , Olaf Bork , Holger Egger , Bastian Budde , Sascha Plug
IPC分类号： C12N7/00
CPC分类号： A61K35/76 , A61K47/6901 , C07K7/06 , C07K7/08 , C07K14/005 , C07K17/02 , C07K17/14 , C07K2319/01 , C12N7/00 , C12N15/1037 , C12N2795/14122 , Y10T442/2508 , Y10T442/2525
摘要： The present invention concerns a system, comprising bacteriophages and particles comprising active agents, in which a first additional peptide is fused to proteins of the bacteriophage, the first additional peptide adheres to the surface of the particle and furthermore a second additional peptide is fused to proteins of the bacteriophage. The second additional peptide can adhere on substrate surfaces. The present invention furthermore concerns the use of the system for delayed release of active agents and also a method for production of the system. The present invention furthermore concerns a method for the selection of phage species from a combinatorial phage population.
摘要翻译： 本发明涉及包含噬菌体和包含活性剂的颗粒的系统，其中第一附加肽与噬菌体的蛋白质融合，第一附加肽粘附到颗粒的表面，此外，第二附加肽与蛋白质融合 的噬菌体。 第二个额外的肽可以粘附在基底表面上。 本发明还涉及该系统用于活性剂的延迟释放的用途以及该系统的生产方法。 本发明还涉及从组合噬菌体群体中选择噬菌体物种的方法。
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7.发明申请SILICA SOL MATERIAL HAVING AT LEAST ONE THERAPEUTICALLY ACTIVE SUBSTANCE FOR PRODUCING BIOLOGICALLY DEGRADABLE AND/OR RESORBABLE SILICA GEL MATERIALS FOR HUMAN MEDICINE AND/OR MEDICAL TECHNOLOGY 审中-公开具有至少一种治疗活性物质的二氧化硅溶胶材料，用于生产用于人类医学和/或医疗技术的生物降解和/或可再生二氧化硅凝胶材料公开(公告)号：US20110123596A1
公开(公告)日：2011-05-26
申请号：US13054449
申请日：2009-07-03
CPC分类号： C08G77/06 , A61L15/64 , A61L27/18 , A61L27/38 , A61L27/58 , C04B35/6224 , C04B2235/408 , C04B2235/441 , C08L83/04
摘要： The invention relates to a novel silica sol material containing at least one therapeutically active ingredient and its use for the production of bioabsorbable and biodegradable silica gel materials with improved properties. The materials, such as, for example, fibers, fleeces, powder, monolith and/or coating are employed, for example, in medical technology and/or human medicine, in particular for wound treatment.
摘要翻译： 本发明涉及含有至少一种治疗活性成分的新型硅溶胶材料及其用于生产具有改进性质的生物可吸收和可生物降解的硅胶材料的用途。 诸如纤维，绒毛，粉末，整料和/或涂层的材料例如在医疗技术和/或人类医学中使用，特别是用于伤口治疗。
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8.发明申请公开(公告)号：US20100285136A1
公开(公告)日：2010-11-11
申请号：US12672096
申请日：2008-08-01
申请人： Stefanie Eiden , Axel Eble , Martin Weiss , Daniel Gordon Duff , Olaf Bork , Holger Egger , Bastian Budde , Sascha Plug
发明人： Stefanie Eiden , Axel Eble , Martin Weiss , Daniel Gordon Duff , Olaf Bork , Holger Egger , Bastian Budde , Sascha Plug
CPC分类号： A61K35/76 , A61K47/6901 , C07K7/06 , C07K7/08 , C07K14/005 , C07K17/02 , C07K17/14 , C07K2319/01 , C12N7/00 , C12N15/1037 , C12N2795/14122 , Y10T442/2508 , Y10T442/2525
摘要： The present invention concerns a system, comprising bacteriophages and particles comprising active agents, in which a first additional peptide is fused to proteins of the bacteriophage, the first additional peptide adheres to the surface of the particle and furthermore a second additional peptide is fused to proteins of the bacteriophage. The second additional peptide can adhere on substrate surfaces. The present invention furthermore concerns the use of the system for delayed release of active agents and also a method for production of the system. The present invention furthermore concerns a method for the selection of phage species from a combinatorial phage population.
摘要翻译： 本发明涉及包含噬菌体和包含活性剂的颗粒的系统，其中第一附加肽与噬菌体的蛋白质融合，第一附加肽粘附到颗粒的表面，此外，第二附加肽与蛋白质融合 的噬菌体。 第二个额外的肽可以粘附在基底表面上。 本发明还涉及该系统用于活性剂的延迟释放的用途以及该系统的生产方法。 本发明还涉及从组合噬菌体群体中选择噬菌体物种的方法。
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