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公开(公告)号：US20110296543A1
公开(公告)日：2011-12-01
申请号：US12324436
申请日：2008-11-26
申请人： Hwai Chang , Eric J. Mathur , Michelle Cayouette , Dan E. Robertson , Philip Hugenholtz , Falk Warnecke , Jared R. Leadbetter , Natalia Ivanova , Peter Luginbuhl , Don Hutchison
发明人： Hwai Chang , Eric J. Mathur , Michelle Cayouette , Dan E. Robertson , Philip Hugenholtz , Falk Warnecke , Jared R. Leadbetter , Natalia Ivanova , Peter Luginbuhl , Don Hutchison
IPC分类号： A01K67/00
CPC分类号： C12Y302/01015 , C12N9/2437 , C12Y302/01004 , C12Y302/01006 , C12Y302/01039 , C12Y302/01067 , C12Y302/01082
摘要： The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs. Polypeptides of the invention can be used in food processing, brewing, bath additives, alcohol production, peptide synthesis, enantioselectivity, hide preparation in the leather industry, waste management and animal degradation, silver recovery in the photographic industry, medical treatment, silk degumming, biofilm degradation, biomass conversion to a biofuel (e.g., a bioethanol, biomethanol, biopropanol or biobutanol, a biodiesel, etc.), biodefense, antimicrobial agents and disinfectants, personal care and cosmetics, biotech reagents, in corn wet milling and pharmaceuticals such as digestive aids and anti-inflammatory (anti-phlogistic) agents.
摘要翻译： 本发明提供了多肽，包括酶，结构蛋白和结合蛋白，编码这些多肽的多核苷酸，以及制备和使用这些多核苷酸和多肽的方法。 本发明的多肽，包括酶和抗体以及核酸可用于工业，实验，食品和饲料加工，营养和药物应用中，例如用于食品和饲料添加剂，着色剂，中性药物，化妆品和药物需求。 本发明的多肽可用于食品加工，酿造，浴添加剂，酒精生产，肽合成，对映选择性，皮革行业中的皮革制备，废物管理和动物降解，摄影工业中的银回收，医疗，丝绸脱胶， 生物膜降解，生物燃料转化为生物燃料（例如生物乙醇，生物甲醇，生物丙醇或生物丁醇，生物柴油等），生物防治剂，抗微生物剂和消毒剂，个人护理和化妆品，生物技术试剂，玉米湿法研磨和药物如 消化助剂和抗炎（抗炎）药剂。
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2.发明授权Xylanases, nucleic acids encoding them and methods for making and using them 有权木聚糖酶，编码它们的核酸以及制备和使用它们的方法公开(公告)号：US08043839B2
公开(公告)日：2011-10-25
申请号：US12279326
申请日：2007-02-14
申请人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
发明人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
IPC分类号： C12N9/24 , C12N1/20 , C12N1/15 , C12N1/16 , C12N1/19 , C12N15/70 , C12P21/06 , C07H21/04 , A01H5/00
CPC分类号： C12N9/248 , A23K10/12 , A23K20/163 , A23L5/00 , A23L7/00 , A23L29/30 , A23L31/00 , A23L31/10 , A23L33/125 , A23V2002/00 , C12N9/2405 , C12N9/2437 , C12N9/2482 , C12N9/2488 , C12N9/2494 , C12P19/02 , C12P19/14 , C12Y302/01008 , D06L4/40 , D06L4/70 , D21C3/003 , D21C9/10 , D21H17/005 , Y02E50/16
摘要： The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal β-1,4-xylosidic linkages or endo-β-1,4-ghicanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及具有木聚糖酶，甘露聚糖酶和/或葡聚糖酶活性的酶，例如催化内部-1,4-木糖苷键或内切-1,4-羟基化酶键的水解; 和/或将线性多糖β-1,4-木聚糖降解成木糖。 因此，本发明提供了分解作为植物细胞壁的主要成分的半纤维素的方法和方法，包括在任何植物或木材或木制品，木材废料，纸浆，纸制品中水解半纤维素的方法和方法， 废纸或副产品。 此外，还提供了设计新的木聚糖酶，甘露聚糖酶和/或葡聚糖酶的方法及其使用方法。 木聚糖酶，甘露聚糖酶和/或葡聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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3.发明申请公开(公告)号：US20110229451A2
公开(公告)日：2011-09-22
申请号：US12660894
申请日：2010-03-05
申请人： Louis Bookbinder , Gregory Frost , Gilbert Keller , Gerhard Frey , Hwai Chang , Jay Short
发明人： Louis Bookbinder , Gregory Frost , Gilbert Keller , Gerhard Frey , Hwai Chang , Jay Short
IPC分类号： A61K38/48 , A61K38/47 , A61P17/02 , A61P19/00 , A61P17/00 , C12N9/50 , C12N9/96 , C07H21/04 , C12N15/63 , C12N5/10
CPC分类号： C12N9/6491 , A61K38/4886 , C12Y304/24007
摘要： Provided are modified matrix metalloprotease (MMP) enzymes that exhibit temperature-dependent activity and uses thereof. The MMPs can be used, for example, to treat ECM-mediated diseases or disorders characterized by increased deposition or accumulation of one or more ECM components.
摘要翻译： 提供了显示温度依赖性活性及其用途的修饰的基质金属蛋白酶（MMP）酶。 MMP可用于例如治疗ECM介导的疾病或特征在于增加一种或多种ECM组分的沉积或积累的疾病。
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4.发明申请XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM 有权XYLANASES，核酸编码它们及其制备和使用方法公开(公告)号：US20090155238A1
公开(公告)日：2009-06-18
申请号：US12279326
申请日：2007-02-14
申请人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
发明人： David Weiner , David Blum , Alexander Varvak , Shaun Healey , Kristine Chang , Geoff Hazlewood , Thomas Todaro , Grace Desantis , Hwai Chang , Connie Jo Hansen , Scott W. Beaver , Thomas Woodward , Charles Hancock
IPC分类号： A61K38/47 , C12N15/11 , C07H21/04 , C12N15/00 , C12N5/06 , C12N1/21 , C12N1/19 , C12P7/02 , A23K1/165 , D06L3/11 , C12P7/10 , D21C3/00 , C12N5/04 , A01K67/027 , A01H5/00 , C12N9/24 , C12P21/04
CPC分类号： C12N9/248 , A23K10/12 , A23K20/163 , A23L5/00 , A23L7/00 , A23L29/30 , A23L31/00 , A23L31/10 , A23L33/125 , A23V2002/00 , C12N9/2405 , C12N9/2437 , C12N9/2482 , C12N9/2488 , C12N9/2494 , C12P19/02 , C12P19/14 , C12Y302/01008 , D06L4/40 , D06L4/70 , D21C3/003 , D21C9/10 , D21H17/005 , Y02E50/16
摘要： The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal β-1,4-xylosidic linkages or endo-β-1,4-ghicanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature.
摘要翻译： 本发明涉及具有木聚糖酶，甘露聚糖酶和/或葡聚糖酶活性的酶，例如催化内部β-1,4-木糖苷键或内-A-1,4-ghicanase键的水解; 和/或将线性多糖β-1,4-木聚糖降解成木糖。 因此，本发明提供了分解作为植物细胞壁的主要成分的半纤维素的方法和方法，包括在任何植物或木材或木制品，木材废料，纸浆，纸制品中水解半纤维素的方法和方法， 废纸或副产品。 此外，还提供了设计新的木聚糖酶，甘露聚糖酶和/或葡聚糖酶的方法及其使用方法。 木聚糖酶，甘露聚糖酶和/或葡聚糖酶在增加的pH和温度下具有增加的活性和稳定性。
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公开(公告)号：US20140166602A1
公开(公告)日：2014-06-19
申请号：US13998792
申请日：2013-12-05
IPC分类号： A47B97/00
CPC分类号： A47B43/00 , A47B97/00 , F16B1/00 , F16B2001/0035
摘要： A supplementary organizer and storage device is disclosed in which the device comprises a central portion having a first side and a second side both descending down from the central portion, the first side having a pocket for receiving an object and the second side having a pocket for receiving an object, the central portion for being placed on top of an appliance and the first side and the second side for draping over top of the appliance.
摘要翻译： 公开了一种补充组织器和存储装置，其中装置包括具有第一侧和第二侧的中心部分，其中心部分从中心部分向下下降，第一侧部具有用于容纳物体的口袋，第二侧部具有用于 接收物体，用于放置在器具顶部的中心部分以及用于悬挂在器具顶部的第一侧和第二侧。
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公开(公告)号：US09402477B2
公开(公告)日：2016-08-02
申请号：US13998792
申请日：2013-12-05
IPC分类号： A47B97/00
CPC分类号： A47B43/00 , A47B97/00 , F16B1/00 , F16B2001/0035
摘要： A supplementary organizer and storage device is disclosed in which the device comprises a central portion having a first side and a second side both descending down from the central portion, the first side having a pocket for receiving an object and the second side having a pocket for receiving an object, the central portion for being placed on top of an appliance and the first side and the second side for draping over top of the appliance.
摘要翻译： 公开了一种补充组织器和存储装置，其中装置包括具有第一侧和第二侧的中心部分，其中心部分从中心部分向下下降，第一侧部具有用于容纳物体的口袋，第二侧部具有用于 接收物体，用于放置在器具顶部的中心部分以及用于悬挂在器具顶部的第一侧和第二侧。
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公开(公告)号：US20060142233A1
公开(公告)日：2006-06-29
申请号：US11269347
申请日：2005-11-08
申请人： Ting-Kai Li , Lucinda Carr , Julie Ellison , Hwai Chang , David Lo
发明人： Ting-Kai Li , Lucinda Carr , Julie Ellison , Hwai Chang , David Lo
IPC分类号： A61K48/00
CPC分类号： C12Q1/6883 , A61K38/1709 , A61K48/00 , C12Q2600/156 , C12Q2600/158 , G01N33/6893 , G01N33/98 , G01N2800/307
摘要： Polynucleotides, polypeptides, kits and methods are provided related to regulated genes characteristic of alcoholism.
摘要翻译： 提供了与酒精中毒特征的调节基因相关的多核苷酸，多肽，试剂盒和方法。
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