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公开(公告)号：US20240335678A1
公开(公告)日：2024-10-10
申请号：US18290618
申请日：2022-06-23
申请人： NATIONAL CANCER CENTER , RAPHARAD INC. , INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY , SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
发明人： Young Kyung LIM , Myeong Soo KIM , Kyeong Yun PARK , Do Hyeon KIM , Sang Soo KIM , Hak Soo KIM , Jong Hwi JEONG , Se Byeong LEE , Dong Ho SHIN , Joo Young KIM , Tae Hyun KIM , Seong Ho MOON , Yang-Gun SUH , Hojin KIM , Kwanghyun JO
IPC分类号： A61N5/10
CPC分类号： A61N5/1042 , A61N2005/1087 , A61N2005/1094 , A61N2005/1095
摘要： The present invention relates to a conversion device for converting a treatment beam for treating a lesion of a subject, comprising: a collimator unit to which the treatment beam is incident and which has a plurality of slits; and a scattering unit that scatters the treatment beam that has passed through the collimator unit.
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公开(公告)号：US12112500B2
公开(公告)日：2024-10-08
申请号：US17468948
申请日：2021-09-08
发明人： Kwang Hoon Sohn , Sung Hun Joung
CPC分类号： G06T7/73 , G06F18/28 , G06V10/40 , G06T2207/20084
摘要： The present disclosure provides an apparatus for cylindrical convolutional neural network operation, and an apparatus and method for object recognition and viewpoint estimation using the same. The present disclosure uses a cylindrical convolutional network to recognize objects in the image and to determine the viewpoint, which cylindrical convolutional network performs a convolution operation while sliding the input image in the direction of rotation of the cylindrical kernel and extracts a plurality of view-specific feature vectors according to angular unit intervals, to identify and recognize objects, as well as to determine the viewpoint from which the objects were photographed.
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公开(公告)号：US12048771B2
公开(公告)日：2024-07-30
申请号：US17283480
申请日：2019-10-04
发明人： Hyungil Jung , Huisuk Yang
CPC分类号： A61K9/7092 , A61M5/422 , A61M37/0015 , A61K9/0021 , A61M2037/0023 , A61M2202/048
摘要： A multifunctional microstructure patch is provided. The multifunctional microstructure patch, according to one embodiment of the present invention, comprises: a base layer having an opening part formed in the center thereof; a plurality of microstructures formed on one surface of the base layer and comprising a first drug; and a cover layer detachably bonded on the other surface of the base layer along the periphery of the opening part, and formed so as to cover the opening part.
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公开(公告)号：US20240229262A1
公开(公告)日：2024-07-11
申请号：US18014833
申请日：2021-07-09
发明人： Dongil Lee , Woojun Choi , Yongsung Jo
IPC分类号： C25B11/095 , C25B3/26
CPC分类号： C25B11/095 , C25B3/26
摘要： Provided is a gold-doped nickel nanocluster having a specific number of gold atoms, nickel atoms, and organothiol-based ligands. The gold atoms, the nickel atoms, and the organothiol-based ligands are bonded in a specific structure, a method for manufacturing the same, an electrode for converting carbon dioxide including the same, and a method for converting carbon dioxide using the same.
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5.发明公开公开(公告)号：US20240228458A1
公开(公告)日：2024-07-11
申请号：US18279348
申请日：2022-04-01
发明人： Tae Bo SIM , Byoung Chul CHO , Han Na CHO , Sandip SENGUPTA , Gannarapu MALLA REDDY , Young Hoon KIM
IPC分类号： C07D401/12 , A61K9/00 , A61K9/20 , A61K9/48 , A61K31/506 , A61K31/53 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K31/551 , A61K31/675 , A61K47/02 , A61K47/26 , C07D239/48 , C07D401/14 , C07D405/14 , C07D417/14 , C07F9/6558
CPC分类号： C07D401/12 , A61K9/0019 , A61K9/2013 , A61K9/2018 , A61K9/2027 , A61K9/2059 , A61K9/4825 , A61K9/4858 , A61K9/4866 , A61K31/506 , A61K31/53 , A61K31/5377 , A61K31/541 , A61K31/55 , A61K31/551 , A61K31/675 , A61K47/02 , A61K47/26 , C07D239/48 , C07D401/14 , C07D405/14 , C07D417/14 , C07F9/65583
摘要： The present invention relates to a pharmaceutical composition for preventing and treating a cancer disease, including lung cancer, caused by abnormal cell growth containing a novel trisubstituted pyrimidine derivative with inhibitory activity against protein kinases, including EGFR, and a pharmaceutically acceptable salt thereof as active ingredients. The novel compound of the present invention has strong inhibitory activity against protein kinases. Particularly, the novel compound of the present invention has potent inhibitory effects against various drug-resistant EGFR mutants (including exon 19 deletion-T790M-C797S-EGFR, L858R-T790M-C797S-EGFR, exon 19 deletion-T790M-EGFR, and L858R-T790M-EGFR) and is useful as a prophylactic and therapeutic agent for cancer diseases caused by these EGFR mutants.
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公开(公告)号：US12027729B2
公开(公告)日：2024-07-02
申请号：US17646249
申请日：2021-12-28
发明人： Wooyoung Shim , Sungsoon Kim
IPC分类号： H01M8/0247 , H01M8/0236 , H01M8/0245 , H01M8/1016
CPC分类号： H01M8/0247 , H01M8/0236 , H01M8/0245 , H01M8/1016 , H01M2300/0068 , H01M2300/0094
摘要： The present disclosure relates to a salinity (NaCl) difference energy generating system and, more particularly, to a method of manufacturing a structural asymmetric ionic transport channel by inducing partial thermal expansion of a laminated film in which vermiculite is re-stacked and an energy generating system capable of producing power by abundant low-cost resources based on the method. The energy power generating device according to the present disclosure is capable of generating power with an easy capacity control and abundant low-cost resources, and the energy power generating device satisfying size characteristics, structural stability characteristics, and furthermore, filtering characteristics may stably produce electrical energy using a solution having a concentration similar to that of seawater and river water.
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7.发明授权公开(公告)号：US12026943B2
公开(公告)日：2024-07-02
申请号：US17644203
申请日：2021-12-14
申请人： Hyundai Motor Company , Kia Corporation , Industry-Academic Cooperation Foundation, Yonsei University
发明人： Jong Won Park , Jin Kyu Hwang , Hyun Ju Kim , Min Seong Park , Won Je Jang , Eun Tai Kim
CPC分类号： G06V20/182 , G01S17/89 , G06N20/10 , G06V10/771 , G06V20/64
摘要： An embodiment device for detecting a boundary of a road in a 3D point cloud using a cascade classifier includes a rule-based classifier configured to determine whether a received LiDAR cluster has a likelihood of becoming a candidate for the boundary of the road using a box parameter surrounding a point cloud constituting the LiDAR cluster and a point parameter, and a learning-based classifier configured to apply a machine-learning scheme to the LiDAR cluster selected as the candidate for the boundary of the road by the rule-based classifier to determine the LiDAR cluster to be the boundary of the road or an object other than the boundary of the road.
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公开(公告)号：US11998543B2
公开(公告)日：2024-06-04
申请号：US17259029
申请日：2019-05-17
发明人： Seok-Gu Kang , Soo Youl Kim
IPC分类号： A61K31/495 , A61K31/11 , A61K31/155 , A61K45/06 , A61P35/04
CPC分类号： A61K31/495 , A61K31/11 , A61K31/155 , A61K45/06 , A61P35/04
摘要： The present disclosure relates to a pharmaceutical composition for treating brain cancer containing an aldehyde inhibitor and an anticancer drug. Since there are many types of brain cancer and the boundary between brain cells and tumor cells in brain cancer is not clear, brain cancer is particularly difficult to treat. The pharmaceutical composition of the present disclosure may further contain a biguanide-based compound as needed, wherein the compound is preferably phenformin. The pharmaceutical composition of the present disclosure is very effective for the treatment and improvement of prognosis of brain cancer, and has remarkable effects of killing cancer cells and inhibiting cancer stem cell characteristics, compared to when each of the active ingredients is administered alone. Thus, it is expected that the pharmaceutical composition of the present disclosure will be widely used in the field of brain cancer treatment.
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公开(公告)号：US20240148713A1
公开(公告)日：2024-05-09
申请号：US18546830
申请日：2022-02-16
发明人： Jae-Ho Cheong , Jae-woo Kim , Bo Kyung YOON
IPC分类号： A61K31/4525 , A61K31/282 , A61K31/4545 , A61K33/243 , A61P35/00 , G01N33/50
CPC分类号： A61K31/4525 , A61K31/282 , A61K31/4545 , A61K33/243 , A61P35/00 , G01N33/5011
摘要： A composition according to the present invention, when used alone, is capable of inhibiting the growth of anticancer drug-resistant cancer by overcoming anticancer drug resistance or enhancing anticancer drug sensitivity, and when co-administered with an anticancer drug, may be used very effectively for the prevention, alleviation or treatment of various cancers, especially anticancer drug-resistant cancer.
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公开(公告)号：US20240145779A1
公开(公告)日：2024-05-02
申请号：US18494866
申请日：2023-10-26
发明人： Sang-Young LEE , Won-Yeong KIM , Hong-I KIM
IPC分类号： H01M10/0567 , H01M10/052 , H01M10/0568 , H01M10/0569
CPC分类号： H01M10/0567 , H01M10/052 , H01M10/0568 , H01M10/0569 , H01M2300/0002 , H01M2300/0028
摘要： Provided is a biphasic electrolyte solution including: an aqueous electrolyte solution layer including a kosmotropic metal salt and water; and a nonaqueous electrolyte solution layer including a second metal salt and a nonaqueous organic solvent, and the biphasic electrolyte solution may provide a battery which satisfies both excellent battery performance and life characteristics.
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