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1.发明授权公开(公告)号：US08815853B2
公开(公告)日：2014-08-26
申请号：US13996866
申请日：2011-12-22
Applicant: Jerome Arigon , Maurice Brollo , Jacques Clement , Romain Combet , Florence Durand , Youssef El Ahmad , Jean-Robert Labrosse , Jean-Philippe Letallec , Baptiste Ronan
Inventor： Jerome Arigon , Maurice Brollo , Jacques Clement , Romain Combet , Florence Durand , Youssef El Ahmad , Jean-Robert Labrosse , Jean-Philippe Letallec , Baptiste Ronan
IPC: C07D413/14 , C07D487/04 , A61K31/5377 , A61K31/519 , C07D487/10 , C07D233/44 , C07D239/12 , C07D239/34
CPC classification number: C07D487/10 , A61K31/519 , A61K31/5377 , C07D233/44 , C07D239/12 , C07D239/34 , C07D413/14 , C07D487/04
Abstract: The invention relates to novel products of formula (Ia) or (Ib): these products being in all the isomeric forms and salts as drugs, notably as anticancer drugs.
Abstract translation: 本发明涉及式（Ia）或（Ib）的新产品：这些产品具有所有的异构体形式和作为药物的盐，特别是抗癌药物。
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公开(公告)号：US5559233A
公开(公告)日：1996-09-24
申请号：US269101
申请日：1994-06-30
Applicant: Claude Bernhart , Jean-Claude Breliere , Jacques Clement , Dino Nisato , Pierre Perreault , Claude Muneaux , Yvette Muneaux
Inventor： Claude Bernhart , Jean-Claude Breliere , Jacques Clement , Dino Nisato , Pierre Perreault , Claude Muneaux , Yvette Muneaux
IPC: C07D233/70 , C07D233/84 , C07D235/02 , C07D239/22 , C07D239/70 , C07D403/10 , C07D417/12 , C07D471/10 , C07D491/10 , C07D521/00 , C07D473/38 , C07D239/36
CPC classification number: C07D235/02 , C07D231/12 , C07D233/56 , C07D233/70 , C07D233/84 , C07D239/22 , C07D239/70 , C07D249/08 , C07D403/10 , C07D417/12 , C07D471/10 , C07D491/10
Abstract: The invention relates to processes for preparing N-substituted heterocyclic compounds of formula (I) ##STR1##
Abstract translation: 本发明涉及制备式（I）的N-取代杂环化合物的方法，
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3.发明申请
公开(公告)号：US20130289031A1
公开(公告)日：2013-10-31
申请号：US13996866
申请日：2011-12-22
Applicant: Jerome Arigon , Maurice Brollo , Jacques Clement , Romain Combet , Florence Durand , Youssef El Ahmad , Jean-Robert Labrosse , Jean-Philippe Letallec , Baptiste Ronan
Inventor： Jerome Arigon , Maurice Brollo , Jacques Clement , Romain Combet , Florence Durand , Youssef El Ahmad , Jean-Robert Labrosse , Jean-Philippe Letallec , Baptiste Ronan
IPC: C07D487/04 , C07D487/10
CPC classification number: C07D487/10 , A61K31/519 , A61K31/5377 , C07D233/44 , C07D239/12 , C07D239/34 , C07D413/14 , C07D487/04
Abstract: The invention relates to novel products of formula (Ia) or (Ib): these products being in all the isomeric forms and salts as drugs, notably as anticancer drugs.
Abstract translation: 本发明涉及式（Ia）或（Ib）的新产品：这些产品具有所有的异构体形式和作为药物的盐，特别是抗癌药物。
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公开(公告)号：US5352788A
公开(公告)日：1994-10-04
申请号：US79866
申请日：1993-06-23
Applicant: Claude Bernhart , Jean-Claude Breliere , Jacques Clement , Dino Nisato , Pierre Perreault , Claude Muneaux , Yvette Muneaux
Inventor： Claude Bernhart , Jean-Claude Breliere , Jacques Clement , Dino Nisato , Pierre Perreault , Claude Muneaux , Yvette Muneaux
IPC: C07D233/70 , C07D233/84 , C07D235/02 , C07D239/22 , C07D239/70 , C07D403/10 , C07D417/12 , C07D471/10 , C07D491/10 , C07D521/00 , C07D239/36
CPC classification number: C07D235/02 , C07D231/12 , C07D233/56 , C07D233/70 , C07D233/84 , C07D239/22 , C07D239/70 , C07D249/08 , C07D403/10 , C07D417/12 , C07D471/10 , C07D491/10
Abstract: The invention relates to processes for preparing N-substituted heterocyclic compounds of formula (I) ##STR1## wherein the substituents are as described in the specification, and to intermediates. The compounds are useful for antagonizing angiotensin II.
Abstract translation: 本发明涉及制备说明书中描述的式（I）的N-取代杂环化合物和中间体的方法。 该化合物可用于拮抗血管紧张素II。
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5.发明授权N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present 失效N-取代的杂环衍生物，其制备方法及其存在的药物组合物
公开(公告)号：US5270317A
公开(公告)日：1993-12-14
申请号：US794497
申请日：1991-11-20
Applicant: Claude Bernhart , Jean-Claude Breliere , Jacques Clement , Dino Nisato , Pierre Perreault , Claude Muneaux , Yvette Muneaux
Inventor： Claude Bernhart , Jean-Claude Breliere , Jacques Clement , Dino Nisato , Pierre Perreault , Claude Muneaux , Yvette Muneaux
IPC: C07D233/70 , C07D233/84 , C07D235/02 , C07D239/22 , C07D239/70 , C07D403/10 , C07D417/12 , C07D471/10 , C07D491/10 , C07D521/00 , A61K31/38 , A61K31/415 , A61K31/505 , C07D473/38
CPC classification number: C07D235/02 , C07D231/12 , C07D233/56 , C07D233/70 , C07D233/84 , C07D239/22 , C07D239/70 , C07D249/08 , C07D403/10 , C07D417/12 , C07D471/10 , C07D491/10
Abstract: The invention relates to N-substituted heterocyclic derivatives and its salts.These derivatives have the formula ##STR1## in which the substituents are as defined in the specification.Application: Angiotensin II antagonists
Abstract translation: 本发明涉及N-取代的杂环衍生物及其盐。 这些衍生物具有式（I），其中取代基如说明书中所定义。 应用：血管紧张素II拮抗剂
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公开(公告)号：US4021696A
公开(公告)日：1977-05-03
申请号：US656053
申请日：1976-02-06
Applicant: Andre Marc Victorin Taxil , Jacques Clement Divoux , Joseph Henri Demaeyer
Abstract: An ultraviolet lamp provides radiation in the 240 to 313 millimicron range for polymerizing photosensitive inks. Accurate quantities of metals and halides are provided by introducing stable gaseous organic compounds of the halogens and reacting the organic compounds with the desired metals to produce their halides.
Abstract translation: 紫外灯提供240至313毫微米范围的辐射，用于聚合光敏油墨。 通过引入卤化物的稳定气态有机化合物并使有机化合物与所需金属反应以产生其卤化物来提供精确量的金属和卤化物。
