公开(公告)号：US08107256B1

公开(公告)日：2012-01-31

申请号：US11925243

申请日：2007-10-26

申请人： Paul Kondrat ,  James Moser ,  Scott Drennan ,  Jonathan Bosloy ,  Charles Mitchell ,  Shawn McAllister

发明人： Paul Kondrat ,  James Moser ,  Scott Drennan ,  Jonathan Bosloy ,  Charles Mitchell ,  Shawn McAllister

IPC分类号： H05K7/14

CPC分类号： H05K7/1429 ,  G06F1/186

摘要： A networking appliance includes a chassis, an off-the-shelf motherboard mounted on said chassis, said motherboard including at least one expansion bus, one or more separately removable expansion module mounted on said chassis, and a number of card slots in the expansion module for accommodating expansion cards. A connection arrangement provides a signal connection between the card slots in the expansion modules and the expansion buses.

摘要翻译： 网络设备包括机箱，安装在所述机架上的现成的主板，所述主板包括至少一个扩展总线，安装在所述机箱上的一个或多个可单独拆卸的扩展模块以及所述扩展模块中的多个卡槽 用于容纳扩展卡。 连接装置提供扩展模块中的卡插槽和扩展总线之间的信号连接。

公开(公告)号：US20110104678A1

公开(公告)日：2011-05-05

申请号：US12884575

申请日：2010-09-17

申请人： Michael James Moser ,  David J. Marshall ,  James R. Prudent ,  Cristopher V. Van Hout ,  Christine A. Larsen

发明人： Michael James Moser ,  David J. Marshall ,  James R. Prudent ,  Cristopher V. Van Hout ,  Christine A. Larsen

IPC分类号： C12N9/99 ,  C12Q1/68

CPC分类号： C12Q1/48

摘要： The present invention provides nucleic acid based polymerase inhibitors and methods for reducing non-specific polymerase extension and amplification in nucleic acid amplification reactions. The polymerase inhibitors provide a double stranded nucleic acid portion that is recognized by a polymerase enzyme as a template for extension but is incapable of being extended by the polymerase enzyme. The polymerase binds to the polymerase inhibitor which sequesters the enzyme until the temperature achieves a level that denatures the double stranded portion of the inhibitor after which the polymerase is released and can then catalyze nucleic acid extension.

摘要翻译： 本发明提供了基于核酸的聚合酶抑制剂和用于在核酸扩增反应中减少非特异性聚合酶延伸和扩增的方法。 聚合酶抑制剂提供双链核酸部分，其被聚合酶识别为扩增模板，但不能被聚合酶延伸。 聚合酶结合聚合酶抑制剂，其将酶螯合，直到温度达到使抑制剂的双链部分变性的水平，其后聚合酶被释放，然后可以催化核酸延伸。

公开(公告)号：US20100221702A1

公开(公告)日：2010-09-02

申请号：US11447734

申请日：2006-06-06

申请人： Michael James Moser

发明人： Michael James Moser

IPC分类号： C12Q1/68

CPC分类号： C12Q1/703 ,  C12Q1/6827 ,  C12Q1/6832 ,  C12Q1/6858 ,  C12Q2600/156 ,  C12Q2527/107 ,  C12Q2525/161 ,  C12Q2525/101 ,  C12Q2549/119

摘要： Disclosed are methods and kits for identifying and characterizing polynucleotide sequences in a sample which may include a heterogeneous sample. Some of the methods and kits are directed to the identification and characterization of a virus in a sample, which may include HIV capable of cause AIDS or AIDS-like symptoms. The virus may be HIV-1, and may also include drug resistant mutations. The methods may include reacting a mixture that includes, in addition to nucleic acid isolated from the sample, at least one oligonucleotide capable of specifically hybridizing to HIV nucleic acid where the oligonucleotide includes at least one non-natural base. In addition, the methods may include detection of one or more mutations in HIV nucleic acid that are associated with drug resistance.

摘要翻译： 公开了用于鉴定和表征可能包括异质样品的样品中的多核苷酸序列的方法和试剂盒。 一些方法和试剂盒旨在鉴定和表征样品中的病毒，其可以包括能够引起AIDS或AIDS样症状的HIV。 病毒可能是HIV-1，也可能包括抗药性突变。 所述方法可以包括使除了从样品分离的核酸之外的至少一种能够与HIV核酸特异性杂交的寡核苷酸的混合物反应，其中寡核苷酸包括至少一个非天然碱基。 此外，所述方法可以包括检测与耐药性相关的HIV核酸中的一个或多个突变。

公开(公告)号：US20080108124A1

公开(公告)日：2008-05-08

申请号：US10551705

申请日：2004-04-01

申请人： Michael James Moser ,  David J. Marshall ,  James R. Prudent ,  Cristopher V. Van Hout ,  Christine A. Larsen

发明人： Michael James Moser ,  David J. Marshall ,  James R. Prudent ,  Cristopher V. Van Hout ,  Christine A. Larsen

IPC分类号： C12N9/99 ,  C07H21/04

CPC分类号： C12Q1/48

摘要： The present invention provides nucleic acid based polymerase inhibitors and methods for reducing non-specific polymerase extension and amplification in nucleic acid amplification reactions. The polymerase inhibitors provide a double stranded nucleic acid portion that is recognized by a polymerase enzyme as a template for extension but is incapable of being extended by the polymerase enzyme. The polymerase binds to the polymerase inhibitor which sequesters the enzyme until the temperature achieves a level that denatures the double stranded portion of the inhibitor after which the polymerase is released and can then catalyze nucleic acid extension.

摘要翻译： 本发明提供了基于核酸的聚合酶抑制剂和用于在核酸扩增反应中减少非特异性聚合酶延伸和扩增的方法。 聚合酶抑制剂提供双链核酸部分，其被聚合酶识别为扩增模板，但不能被聚合酶延伸。 聚合酶结合聚合酶抑制剂，其将酶螯合，直到温度达到使抑制剂的双链部分变性的水平，其后聚合酶被释放，然后可以催化核酸延伸。

公开(公告)号：US20050185961A1

公开(公告)日：2005-08-25

申请号：US11110604

申请日：2005-04-20

申请人： Ketan Bhalla ,  Andre Lortie ,  Kyle Edginton ,  James Moser ,  Gamal Refai-Ahmed ,  Marc Nadeau ,  Ross Saunders ,  Lee Choong

发明人： Ketan Bhalla ,  Andre Lortie ,  Kyle Edginton ,  James Moser ,  Gamal Refai-Ahmed ,  Marc Nadeau ,  Ross Saunders ,  Lee Choong

IPC分类号： H04J3/04 ,  H04J3/16 ,  H04J14/02 ,  H04Q11/00 ,  H04Q11/04 ,  H04J4/00

CPC分类号： H04J14/02 ,  H04J3/04 ,  H04J3/1611 ,  H04J2203/0025 ,  H04J2203/0026 ,  H04Q11/0071

摘要： A field reconfigurable muxponder for use in an optical transport system. The muxponder includes one or more tributary cards, where each tributary card is adapted to receive an optical data signal and conditions the optical data signal into an intermediate data signal constituted in accordance with a tributary interface format. In this way, the muxponder is able to aggregate optical data signals having different protocols and/or different data rates. The muxponder further includes a chassis that is adapted to receive a predefined number of tributary cards and outputs an optical system signal independently from the availability of the optical data signals from the tributary cards. The tributary cards and the chassis integrally form one line card.

摘要翻译： 一种用于光传输系统的现场可重配置复用应答器。 复用器包括一个或多个辅助卡，其中每个支路卡适于接收光学数据信号，并将光学数据信号调节成根据支流接口格式构成的中间数据信号。 以这种方式，复用器能够聚合具有不同协议和/或不同数据速率的光数据信号。 复用器还包括适于接收预定数量的辅助卡并且独立于来自辅助卡的光学数据信号的可用性而输出光学系统信号的机箱。 支流卡和底盘一体形成一张线卡。

公开(公告)号：US07703864B2

公开(公告)日：2010-04-27

申请号：US11623395

申请日：2007-01-16

申请人： James Moser

发明人： James Moser

IPC分类号： A47B43/02 ,  A47B47/06 ,  A47F5/11

CPC分类号： B65D5/5213

摘要： A rectilinear folded and glued container with tiered shelves has multiple shelf panels cut out of a front panel with which the shelf panels, and main container front, side and back panels are integrally connected. The container has an internally placed shelf-raising panel that is attached to the shelf panels as part of a fold and glue processing technique that produces a knocked down flat container to be erected. The shelf raising panel preferably is an integral panel that is separate from the main container panels so as to be relatively movable, and is affixed to the shelf panels. Displacing or translating the shelf-raising panel during erection of the container from its knocked-down-flat configuration articulates the shelves into position. The shelf raising panel can be captured between top and bottom ends of the erected container, thus fixing the erected container and articulated shelves in a rigid shape.

摘要翻译： 具有分层架的直线折叠和胶合容器具有从前面板切割出的多个搁板，搁板和主容器前面，侧面和后面板一体连接。 容器具有内部放置的升降板，其附接到搁板，作为折叠和胶水加工技术的一部分，其产生要架设的被撞倒的扁平容器。 搁板提升板优选地是与主容器面板分离以便相对可移动并且固定到搁板的整体面板。 在将容器从其倒下的扁平构造中架起来时，将搁板提升面板放置或平移将货架定位到位。 搁架提升面板可以被捕获在直立的容器的顶端和底端之间，从而将竖立的容器和铰接的搁架固定成刚性的形状。

公开(公告)号：US06915036B2

公开(公告)日：2005-07-05

申请号：US10269356

申请日：2002-10-11

申请人： Ketan Bhalla ,  Andre Lortie ,  Kyle Edginton ,  James Moser ,  Gamal Refai-Ahmed ,  Marc Nadeau ,  Ross Saunders ,  Lee Shyue Choong

发明人： Ketan Bhalla ,  Andre Lortie ,  Kyle Edginton ,  James Moser ,  Gamal Refai-Ahmed ,  Marc Nadeau ,  Ross Saunders ,  Lee Shyue Choong

IPC分类号： H04J3/04 ,  H04J3/16 ,  H04J14/02 ,  H04Q11/00 ,  H04Q11/04 ,  G02B6/28

CPC分类号： H04J14/02 ,  H04J3/04 ,  H04J3/1611 ,  H04J2203/0025 ,  H04J2203/0026 ,  H04Q11/0071

摘要： A field reconfigurable muxponder for use in an optical transport system. The muxponder includes one or more tributary cards, where each tributary card is adapted to receive an optical data signal and conditions the optical data signal into an intermediate data signal constituted in accordance with a tributary interface format. In this way, the muxponder is able to aggregate optical data signals having different protocols and/or different data rates. The muxponder further includes a chassis that is adapted to receive a predefined number of tributary cards and outputs an optical system signal independently from the availability of the optical data signals from the tributary cards. The tributary cards and the chassis integrally form one line card.

公开(公告)号：US06853696B1

公开(公告)日：2005-02-08

申请号：US09466665

申请日：1999-12-20

申请人： James Moser ,  Matthew D. Brown ,  Michel Pigeon ,  Marc A. Nadeau ,  Chung Y. Wu

发明人： James Moser ,  Matthew D. Brown ,  Michel Pigeon ,  Marc A. Nadeau ,  Chung Y. Wu

IPC分类号： H03L7/087 ,  H03L7/091 ,  H03L7/095 ,  H03L7/113 ,  H04L7/033 ,  H03D3/24

CPC分类号： H03L7/095 ,  H03L7/087 ,  H03L7/091 ,  H03L7/113 ,  H04L7/033

摘要： A system for recovering a clock signal from a data signal is described. The system uses an oscillator adapted to generate an oscillator output signal, a first detecting circuit for obtaining a coarse frequency-lock condition between the data signal and a recovered clock signal, a second detecting circuit for obtaining a phase-locked condition between the data signal and the recovered clock signal, a lock-detecting circuit responsive to the first detecting circuit for detecting an out-of-lock condition between the data signal and the recovered clock signal, and a control circuit responsive to the lock-detecting circuits and adapted to control the oscillator to generate an oscillator output signal on the basis of the first detecting circuit during an out-of-lock condition, and otherwise to generate the oscillator output signal on the basis of the second detecting circuit. The advantages include a much wider pull-in range for frequency acquisition, and an accurate and robust measure of a quality of received data.

摘要翻译： 描述用于从数据信号恢复时钟信号的系统。 该系统使用适于产生振荡器输出信号的振荡器，用于获得数据信号与恢复的时钟信号之间的粗略频率锁定状态的第一检测电路，用于获得数据信号之间的锁相状态的第二检测电路 以及恢复的时钟信号，响应于第一检测电路的锁定检测电路，用于检测数据信号和恢复的时钟信号之间的失锁状态，以及响应于锁定检测电路的控制电路， 控制振荡器以在失锁状态下基于第一检测电路产生振荡器输出信号，否则将根据第二检测电路产生振荡器输出信号。 优点包括频率采集的更宽的拉入范围以及接收数据质量的准确和可靠的测量。

公开(公告)号：US08293472B2

公开(公告)日：2012-10-23

申请号：US11447734

申请日：2006-06-06

申请人： Michael James Moser

发明人： Michael James Moser

IPC分类号： C12Q1/68 ,  C12P19/34

CPC分类号： C12Q1/703 ,  C12Q1/6827 ,  C12Q1/6832 ,  C12Q1/6858 ,  C12Q2600/156 ,  C12Q2527/107 ,  C12Q2525/161 ,  C12Q2525/101 ,  C12Q2549/119

摘要： Disclosed are methods for identifying and characterizing polynucleotide sequences in a sample which may include a heterogeneous sample. Some of the methods are directed to the identification and characterization of a virus in a sample, which may include HIV capable of cause AIDS or AIDS-like symptoms. The virus may be HIV-1, and may also include drug resistant mutations. The methods may include reacting a mixture that includes, in addition to nucleic acid isolated from the sample, at least one oligonucleotide capable of specifically hybridizing to HIV nucleic acid where the oligonucleotide includes at least one non-natural base. In addition, the methods may include detection of one or more mutations in HIV nucleic acid that are associated with drug resistance.

摘要翻译： 公开了用于鉴定和表征可能包括异质样品的样品中的多核苷酸序列的方法。 一些方法涉及鉴定和表征样品中的病毒，其可以包括能够引起AIDS或AIDS样症状的HIV。 病毒可能是HIV-1，也可能包括抗药性突变。 所述方法可以包括使除了从样品分离的核酸之外的至少一种能够与HIV核酸特异性杂交的寡核苷酸的混合物反应，其中寡核苷酸包括至少一个非天然碱基。 此外，所述方法可以包括检测与耐药性相关的HIV核酸中的一个或多个突变。

公开(公告)号：US20080169339A1

公开(公告)日：2008-07-17

申请号：US11623395

申请日：2007-01-16

申请人： James Moser

发明人： James Moser

IPC分类号： B65D5/36

CPC分类号： B65D5/5213

摘要： A rectilinear folded and glued container with tiered shelves has multiple shelf panels cut out of a front panel with which the shelf panels, and main container front, side and back panels are integrally connected. The container has an internally placed shelf-raising panel that is attached to the shelf panels as part of a fold and glue processing technique that produces a knocked down flat container to be erected. The shelf raising panel preferably is an integral panel that is separate from the main container panels so as to be relatively movable, and is affixed to the shelf panels. Displacing or translating the shelf-raising panel during erection of the container from its knocked-down-flat configuration articulates the shelves into position. The shelf raising panel can be captured between top and bottom ends of the erected container, thus fixing the erected container and articulated shelves in a rigid shape.

摘要翻译： 具有分层架的直线折叠和胶合容器具有从前面板切割出的多个搁板，搁板和主容器前面，侧面和后面板一体连接。 容器具有内部放置的升降板，其附接到搁板，作为折叠和胶水加工技术的一部分，其产生将被竖立的被撞倒的扁平容器。 搁板提升板优选地是与主容器面板分离以便相对可移动并且固定到搁板的整体面板。 在将容器从其倒下的扁平构造中架起来时，将搁板提升面板放置或平移将货架定位到位。 搁架提升面板可以被捕获在直立的容器的顶端和底端之间，从而将竖立的容器和铰接的搁架固定成刚性的形状。