-
公开(公告)号:US09161714B2
公开(公告)日:2015-10-20
申请号:US12195942
申请日:2008-08-21
申请人: Joerg Martini , Richard H. Bruce , Francisco E. Torres , Peter Kiesel , Michael I. Recht , Jeffrey N. Roe
发明人: Joerg Martini , Richard H. Bruce , Francisco E. Torres , Peter Kiesel , Michael I. Recht , Jeffrey N. Roe
IPC分类号: A61B5/00 , A61B5/1459 , A61B5/145 , G01N21/33 , G01N21/359
CPC分类号: A61B5/1459 , A61B5/0031 , A61B5/14532 , G01N21/33 , G01N21/359
摘要: A system and method is provided for detecting concentration of an analyte in a fluid. A first container includes (i) an optical cavity detection region, (ii) a reservoir for one or more modifiers of one or more optical properties of the optical cavity detection region, and (iii) a set of one or more bounding regions through which objects in the fluid can transfer into the container. The optical cavity detection region and the reservoir define separate areas of the first container. The movement of the one or more modifiers between the reservoir and the optical cavity detection region is responsive to changes in concentration of the analyte. A second container includes an optical cavity detection region, and a set of one or more bounding regions through which objects in the fluid can transfer into the container. Also provided are optical components for guiding light into the optical cavity detection regions of the first and second containers.
摘要翻译: 提供了用于检测流体中分析物的浓度的系统和方法。 第一容器包括(i)光腔检测区域,(ii)用于一个或多个光腔检测区域的一个或多个光学特性的修改器的储存器,以及(iii)一组或多个边界区域, 流体中的物体可以转移到容器中。 光腔检测区域和储存器限定第一容器的分开的区域。 储存器和光腔检测区域之间的一个或多个改性剂的运动响应于分析物浓度的变化。 第二容器包括光学腔检测区域和一组一个或多个界限区域,流体中的物体可通过该区域传送到容器中。 还提供了用于将光引导到第一和第二容器的光学腔检测区域中的光学部件。
-
公开(公告)号:US08986223B2
公开(公告)日:2015-03-24
申请号:US13466467
申请日:2012-05-08
申请人: Jeffrey N. Roe , Steven N. Roe
发明人: Jeffrey N. Roe , Steven N. Roe
CPC分类号: A61B5/14546 , A61B5/1411 , A61B5/150022 , A61B5/150099 , A61B5/150358 , A61B5/150419 , A61B5/150473 , A61B5/150503 , A61B5/150633 , A61B5/150702 , A61B5/150717 , A61B5/15113 , A61B5/15117 , A61B5/1519 , A61B5/157 , A61B10/0045 , A61B2562/0295 , G01N33/48 , G01N33/48764 , G01N2001/028 , G01N2035/00019 , Y10T436/25
摘要: A bodily fluid sampling device includes a piercing device and a sensor enclosed in a housing. A cassette, which contains test media, is positioned proximal to the sensor so that the sensor is able to analyze a bodily fluid sample collected on the test media. The cassette includes a supply portion from which unused test media is supplied and a storage portion in which contaminated test media is stored after exposure to the bodily fluid. The cassette is adapted to collect a series of bodily fluid samples without requiring disposal of the test media.
-
公开(公告)号:US08696596B2
公开(公告)日:2014-04-15
申请号:US12644528
申请日:2009-12-22
CPC分类号: A61B5/157 , A61B5/14532 , A61B5/150022 , A61B5/150076 , A61B5/150083 , A61B5/150183 , A61B5/15019 , A61B5/150213 , A61B5/150229 , A61B5/150236 , A61B5/150244 , A61B5/150343 , A61B5/150358 , A61B5/150396 , A61B5/150503 , A61B5/150946 , A61B5/150977 , A61B5/15113 , A61B5/15117 , A61B5/1513 , A61B5/15136 , A61B5/1519 , A61B5/15196
摘要: A device and method for lancing a patient, virtually simultaneously producing and collecting a small fluid sample from a body. The device comprises a blood collection system including a lancing needle (16), drive mechanism (11), kneading or vibration mechanism (25), optional suction system (7), and sample ejection mechanism. The device is preferably sized to be hand-held in one hand and operable with one hand. The device can optionally contain integral testing or analysis component (83) for receiving the sample and providing testing or analysis indication or readout for the user. A method involves piercing the skin at a rapid rate, kneading the surrounding area by ultrasonic action, piezoelectric or mechanical oscillation to stimulate the blood flow from the wound, drawing the fluid using a pumping system.
摘要翻译: 用于穿刺患者的装置和方法,实际上同时从身体产生和收集小的液体样品。 该装置包括采血系统,其包括穿刺针(16),驱动机构(11),揉搓或振动机构(25),可选的抽吸系统(7)和样品排出机构。 该装置的尺寸优选为一只手中的手持式并且用一只手可操作。 该设备可以可选地包含用于接收样品并为用户提供测试或分析指示或读出的整体测试或分析组件(83)。 一种方法包括以快速的速度刺穿皮肤,通过超声波作用,压电或机械振动来捏合周围区域,以刺激来自伤口的血液流动,使用泵送系统拉伸流体。
-
公开(公告)号:US20120289864A1
公开(公告)日:2012-11-15
申请号:US13561672
申请日:2012-07-30
申请人: Joel S. Douglas , Jeffrey N. Roe , Henry M. Grage
发明人: Joel S. Douglas , Jeffrey N. Roe , Henry M. Grage
CPC分类号: A61B5/15194 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150083 , A61B5/150412 , A61B5/150503 , A61B5/15111 , A61B5/15113 , A61B5/15117 , A61B5/1519 , A61B10/0045 , A61B2010/008 , A61B2017/00765 , A61B2562/0295
摘要: A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.
摘要翻译: 体液例如血液或间质液的样品通过使用者的皮肤的一部分优选在指尖以外的区域穿刺而从身体获得,以形成切口。 在针从切口移除之后,施加力以形成与切口周围关系的形成凹陷的身体组织的环的方式来压下皮肤,导致切口凸起并且切口的两侧打开,由此 体液通过切口的开口被迫出来。 刺激构件安装到用于施加力的刺血针承载壳体的端部。 刺激器构件可以相对于壳体可移动,并且可以被加热或振动以促进体液的移动。
-
公开(公告)号:US08257277B2
公开(公告)日:2012-09-04
申请号:US12848282
申请日:2010-08-02
申请人: Jeffrey N. Roe , Steven N. Roe
发明人: Jeffrey N. Roe , Steven N. Roe
CPC分类号: A61B5/14546 , A61B5/1411 , A61B5/150022 , A61B5/150099 , A61B5/150358 , A61B5/150419 , A61B5/150473 , A61B5/150503 , A61B5/150633 , A61B5/150702 , A61B5/150717 , A61B5/15113 , A61B5/15117 , A61B5/1519 , A61B5/157 , A61B10/0045 , A61B2562/0295 , G01N33/48 , G01N33/48764 , G01N2001/028 , G01N2035/00019 , Y10T436/25
摘要: A bodily fluid sampling device includes a piercing device and a sensor enclosed in a housing. A cassette, which contains test media, is positioned proximal to the sensor so that the sensor is able to analyze a bodily fluid sample collected on the test media. The cassette includes a supply portion from which unused test media is supplied and a storage portion in which contaminated test media is stored after exposure to the bodily fluid. The cassette is adapted to collect a series of bodily fluid samples without requiring disposal of the test media.
摘要翻译: 体液采样装置包括穿孔装置和封闭在壳体中的传感器。 包含测试介质的盒子位于传感器的近侧,使得传感器能够分析在测试介质上收集的体液样品。 盒子包括供应部分,从该供应部分供应未使用的试验介质和存储部分,在存储部分中暴露于体液之后存储被污染的测试介质。 该盒适于收集一系列体液样品,而不需要处理测试介质。
-
公开(公告)号:US20120215084A1
公开(公告)日:2012-08-23
申请号:US13462902
申请日:2012-05-03
CPC分类号: A61B10/0045 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150213 , A61B5/150358 , A61B5/150412 , A61B5/150755 , A61B5/150824 , A61B5/151 , A61B5/15107 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B2010/0003 , A61B2010/008 , A61B2017/00765 , A61B2562/0295
摘要: A sampling device for sampling body fluid includes a lancet for making an incision, a capillary tube for drawing-up body fluid from the incision, and a test strip affixed to an upper end of the capillary tube for receiving the fluid. An absorbent pad can be disposed between the test strip and capillary tube for spreading-out the fluid being transferred to the test strip. An on-site analyzer such as an optical analyzer and/or an electrochemical analyzer can be mounted in the device for analyzing the fluid. Alternatively, a test strip can be slid through a slot formed in the bottom end of the device so that by passing the device against the skin after an incision has been formed, the test strip will directly contact body fluid emanating from the incision.
摘要翻译: 用于体液取样的采样装置包括用于切开的刺血针,用于从切口吸取体液的毛细管,以及固定到毛细管的上端以接收流体的测试条。 可以在测试条和毛细管之间设置吸收垫,以便将被传送到测试条的流体展开。 可以在用于分析流体的装置中安装诸如光学分析仪和/或电化学分析仪的现场分析仪。 或者,测试条可以滑动通过形成在装置的底端的槽,使得通过在形成切口之后使装置抵靠皮肤,测试条将直接接触从切口发出的体液。
-
公开(公告)号:US20100331731A1
公开(公告)日:2010-12-30
申请号:US12845832
申请日:2010-07-29
IPC分类号: A61B5/151
CPC分类号: A61B5/157 , A61B5/14532 , A61B5/150022 , A61B5/150076 , A61B5/150083 , A61B5/150183 , A61B5/15019 , A61B5/150213 , A61B5/150229 , A61B5/150236 , A61B5/150244 , A61B5/150343 , A61B5/150358 , A61B5/150396 , A61B5/150503 , A61B5/150946 , A61B5/150977 , A61B5/15113 , A61B5/15117 , A61B5/1513 , A61B5/15136 , A61B5/1519 , A61B5/15196
摘要: A device and method for lancing a patient, virtually simultaneously producing and collecting a small fluid sample from a body. The device comprises a blood collection system including a lancing needle, drive mechanism, kneading or vibration mechanism, optional suction system, and sample ejection mechanism. The device is preferably sized to be hand-held in one hand and operable with one hand. The device can optionally contain integral testing or analysis component for receiving the sample and providing testing or analysis indication or readout for the user. In one configuration, the lancing needle may be withdrawn very slightly from the point of maximum penetration to create an opening in which blood can pool before being suctioned through to device.
摘要翻译: 用于穿刺患者的装置和方法,实际上同时从身体产生和收集小的液体样品。 该装置包括采血系统,其包括穿刺针,驱动机构,捏合或振动机构,可选的抽吸系统和样品排出机构。 该装置的尺寸优选为一只手中的手持式并且用一只手可操作。 该设备可以可选地包含用于接收样品的集成测试或分析组件,并为用户提供测试或分析指示或读数。 在一种配置中,可以从最大穿透点非常轻微地抽出穿刺针,以产生血液在被吸入到装置之前可以集中的开口。
-
公开(公告)号:US20100317935A1
公开(公告)日:2010-12-16
申请号:US12848282
申请日:2010-08-02
申请人: Jeffrey N. Roe , Steven N. Roe
发明人: Jeffrey N. Roe , Steven N. Roe
CPC分类号: A61B5/14546 , A61B5/1411 , A61B5/150022 , A61B5/150099 , A61B5/150358 , A61B5/150419 , A61B5/150473 , A61B5/150503 , A61B5/150633 , A61B5/150702 , A61B5/150717 , A61B5/15113 , A61B5/15117 , A61B5/1519 , A61B5/157 , A61B10/0045 , A61B2562/0295 , G01N33/48 , G01N33/48764 , G01N2001/028 , G01N2035/00019 , Y10T436/25
摘要: A bodily fluid sampling device includes a piercing device and a sensor enclosed in a housing. A cassette, which contains test media, is positioned proximal to the sensor so that the sensor is able to analyze a bodily fluid sample collected on the test media. The cassette includes a supply portion from which unused test media is supplied and a storage portion in which contaminated test media is stored after exposure to the bodily fluid. The cassette is adapted to collect a series of bodily fluid samples without requiring disposal of the test media.
摘要翻译: 体液采样装置包括穿孔装置和封闭在壳体中的传感器。 包含测试介质的盒子位于传感器的近侧,使得传感器能够分析在测试介质上收集的体液样品。 盒子包括供应部分,从该供应部分供应未使用的试验介质和存储部分,在存储部分中暴露于体液之后存储被污染的测试介质。 该盒适于收集一系列体液样品,而不需要处理测试介质。
-
公开(公告)号:US07841991B2
公开(公告)日:2010-11-30
申请号:US10607347
申请日:2003-06-26
申请人: Joel S. Douglas , Jeffrey N. Roe , Henry M. Grage
发明人: Joel S. Douglas , Jeffrey N. Roe , Henry M. Grage
IPC分类号: A61B5/00
CPC分类号: A61B5/15194 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150083 , A61B5/150412 , A61B5/150503 , A61B5/15111 , A61B5/15113 , A61B5/15117 , A61B5/1519 , A61B10/0045 , A61B2010/008 , A61B2017/00765 , A61B2562/0295
摘要: A sample of a body fluid such as blood or interstitial fluid is obtained from a body by lancing a portion of a user's skin, preferably in an area other than a finger tip, to form an incision. After the needle has been removed from the incision, a force is applied to depress the skin in a manner forming a ring of depressed body tissue in surrounding relationship to the incision, causing the incision to bulge and the sides of the incision to open, whereby body fluid is forced out through the opening of the incision. A stimulator member is mounted to an end of a lancet-carrying housing for applying the force. The stimulator member can be movable relative to the housing, and can be either heated or vibrated to promote movement of the body fluid.
摘要翻译: 体液例如血液或间质液的样品通过使用者的皮肤的一部分优选在指尖以外的区域穿刺而从身体获得,以形成切口。 在针从切口移除之后,施加力以形成与切口周围关系的凹陷的身体组织环的方式来压下皮肤,导致切口凸起并且切口的两侧打开,由此 体液通过切口的开口被迫出来。 刺激构件安装到用于施加力的刺血针承载壳体的端部。 刺激器构件可以相对于壳体可移动,并且可以被加热或振动以促进体液的移动。
-
公开(公告)号:US07727168B2
公开(公告)日:2010-06-01
申请号:US11765045
申请日:2007-06-19
CPC分类号: A61B10/0045 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150213 , A61B5/150358 , A61B5/150412 , A61B5/150755 , A61B5/150824 , A61B5/151 , A61B5/15107 , A61B5/15117 , A61B5/1519 , A61B5/15194 , A61B5/157 , A61B2010/0003 , A61B2010/008 , A61B2017/00765 , A61B2562/0295
摘要: A sampling device for sampling body fluid includes a lancet for making an incision, a capillary tube for drawing-up body fluid from the incision, and a test strip affixed to an upper end of the capillary tube for receiving the fluid. An absorbent pad can be disposed between the test strip and capillary tube for spreading-out the fluid being transferred to the test strip. An on-site analyzer such as an optical analyzer and/or an electrochemical analyzer can be mounted in the device for analyzing the fluid. Alternatively, a test strip can be slid through a slot formed in the bottom end of the device so that by passing the device against the skin after an incision has been formed, the test strip will directly contact body fluid emanating from the incision.
-
-
-
-
-
-
-
-
-