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公开(公告)号:USRE39575E1
公开(公告)日:2007-04-17
申请号:US10996325
申请日:2004-11-23
申请人: Edward R. Bacon , Sankar Chatterjee , Derek Dunn , John P. Mallamo , Jeffry L. Vaught , Matthew S. Miller
发明人: Edward R. Bacon , Sankar Chatterjee , Derek Dunn , John P. Mallamo , Jeffry L. Vaught , Matthew S. Miller
IPC分类号: C07D401/02 , A61K31/44
CPC分类号: C07D495/04 , C07C317/44 , C07C323/60 , C07C2603/18 , C07D207/16 , C07D207/416 , C07D211/88 , C07D213/34 , C07D219/04 , C07D231/54 , C07D233/64 , C07D261/08 , C07D263/16 , C07D263/32 , C07D263/34 , C07D275/02 , C07D277/26 , C07D277/56 , C07D307/68 , C07D311/84 , C07D333/18 , C07D335/14 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/06
摘要: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
摘要翻译: 本发明涉及取代的硫代乙酰胺的化学组成,其制备方法和组合物在治疗疾病中的用途。
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公开(公告)号:US06670358B2
公开(公告)日:2003-12-30
申请号:US10014645
申请日:2001-10-26
申请人: Edward R. Bacon , Sankar Chatterjee , Derek Dunn , John P. Mallamo , Matthew S. Miller , Rabindranath Tripathy , Jeffry L. Vaught
发明人: Edward R. Bacon , Sankar Chatterjee , Derek Dunn , John P. Mallamo , Matthew S. Miller , Rabindranath Tripathy , Jeffry L. Vaught
IPC分类号: C07D21302
CPC分类号: C07D263/34 , C07C317/44 , C07C323/60 , C07C323/63 , C07C2603/18 , C07C2603/32 , C07D207/16 , C07D207/273 , C07D207/416 , C07D211/88 , C07D213/34 , C07D219/04 , C07D231/54 , C07D233/64 , C07D261/08 , C07D263/16 , C07D263/32 , C07D275/02 , C07D277/26 , C07D277/56 , C07D307/68 , C07D311/84 , C07D333/18 , C07D335/14 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/06 , C07D495/04
摘要: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
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公开(公告)号:US06492396B2
公开(公告)日:2002-12-10
申请号:US09855228
申请日:2001-05-15
申请人: Edward R. Bacon , Sankar Chatterjee , Derek Dunn , John P. Mallamo , Jeffry L. Vaught , Matthew S. Miller
发明人: Edward R. Bacon , Sankar Chatterjee , Derek Dunn , John P. Mallamo , Jeffry L. Vaught , Matthew S. Miller
IPC分类号: C07D40102
CPC分类号: C07D495/04 , C07C317/44 , C07C323/60 , C07C2603/18 , C07D207/16 , C07D207/416 , C07D211/88 , C07D213/34 , C07D219/04 , C07D231/54 , C07D233/64 , C07D261/08 , C07D263/16 , C07D263/32 , C07D263/34 , C07D275/02 , C07D277/26 , C07D277/56 , C07D307/68 , C07D311/84 , C07D333/18 , C07D335/14 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/06
摘要: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
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公开(公告)号:US06919367B2
公开(公告)日:2005-07-19
申请号:US10716238
申请日:2003-11-18
申请人: Edward R. Bacon , Sankar Chatterjee , Derek Dunn , John P. Mallamo , Matthew S. Miller , Rabindranath Tripathy , Jeffry L. Vaught
发明人: Edward R. Bacon , Sankar Chatterjee , Derek Dunn , John P. Mallamo , Matthew S. Miller , Rabindranath Tripathy , Jeffry L. Vaught
IPC分类号: C07D295/08 , A61K31/165 , A61K31/166 , A61K31/341 , A61K31/352 , A61K31/381 , A61K31/40 , A61K31/4015 , A61K31/4025 , A61K31/415 , A61K31/421 , A61K31/422 , A61K31/426 , A61K31/427 , A61K31/4402 , A61K31/4406 , A61K31/4436 , A61K31/45 , A61K31/4535 , A61K31/5377 , A61P1/00 , A61P1/14 , A61P9/10 , A61P11/00 , A61P25/00 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/28 , A61P43/00 , C07C317/44 , C07C323/60 , C07C323/61 , C07D207/16 , C07D207/26 , C07D207/273 , C07D207/40 , C07D207/416 , C07D211/88 , C07D213/34 , C07D213/40 , C07D219/04 , C07D231/54 , C07D233/54 , C07D261/08 , C07D263/10 , C07D263/16 , C07D263/32 , C07D263/34 , C07D275/02 , C07D277/26 , C07D277/56 , C07D307/68 , C07D311/84 , C07D333/18 , C07D335/14 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/06 , C07D495/04 , C07D498/04 , C07D401/02 , A61K31/44
CPC分类号: C07D263/34 , C07C317/44 , C07C323/60 , C07C323/63 , C07C2603/18 , C07C2603/32 , C07D207/16 , C07D207/273 , C07D207/416 , C07D211/88 , C07D213/34 , C07D219/04 , C07D231/54 , C07D233/64 , C07D261/08 , C07D263/16 , C07D263/32 , C07D275/02 , C07D277/26 , C07D277/56 , C07D307/68 , C07D311/84 , C07D333/18 , C07D335/14 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/06 , C07D495/04
摘要: The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases.
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5.Combination of tyrosine kinase inhibitor and chemical castration to treat prostate cancer 失效
标题翻译: 组合酪氨酸激酶抑制剂和化学去势治疗前列腺癌公开(公告)号:US5985877A
公开(公告)日:1999-11-16
申请号:US133567
申请日:1998-08-13
申请人: Craig A. Dionne , John Isaacs , Jeffry L. Vaught
发明人: Craig A. Dionne , John Isaacs , Jeffry L. Vaught
IPC分类号: C07D498/22 , A61K31/55 , A61K31/553 , A61K31/565 , A61K38/04 , A61K38/09 , A61K45/06 , A61P13/08 , A61P35/00 , A61P43/00
CPC分类号: A61K45/06 , A61K31/55 , A61K31/565 , A61K38/04 , A61K38/09
摘要: A method of treating prostate cancer by co-administering a tyrosine kinase inhibitor such as an indolocarbazole and a chemical castration agent is disclosed. A composition containing a tyrosine kinase inhibitor and a chemical castration agent is also disclosed.
摘要翻译: 公开了通过共同施用酪氨酸激酶抑制剂如吲哚并咔唑和化学去角质剂来治疗前列腺癌的方法。 还公开了含有酪氨酸激酶抑制剂和化学去角质剂的组合物。
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