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    Device and method for detecting biomolecules using adsorptive medium and field effect transistor
    2.
    发明授权
    Device and method for detecting biomolecules using adsorptive medium and field effect transistor 有权
    用吸附介质和场效应晶体管检测生物分子的装置和方法

    公开(公告)号：US08198658B2

    公开(公告)日：2012-06-12

    申请号：US12125506

    申请日：2008-05-22

    申请人： Jeo Young Shim ,  Kyu Tae Yoo ,  Won Seok Chung ,  Jung Im Han

    发明人： Jeo Young Shim ,  Kyu Tae Yoo ,  Won Seok Chung ,  Jung Im Han

    IPC分类号： H01L29/72

    CPC分类号： G01N27/4145

    摘要： A device for detecting biomolecules includes: a semiconductor substrate; a source region and a drain region separately provided at the substrate; a chamber formed at the substrate including a region between the source region and the drain region, the chamber configured to contain a sample including the biomolecules; and an electrode which applies a voltage to the sample in the chamber. The biomolecules are mobile with respect to the electrode and sample. Methods for detecting biomolecules are also disclosed.

    摘要翻译： 用于检测生物分子的装置包括：半导体衬底; 分别设置在所述基板上的源极区域和漏极区域; 在所述基板上形成的室，所述室包括所述源区域和所述漏极区域之间的区域，所述室被配置为容纳包含所述生物分子的样品; 以及向室中的样品施加电压的电极。 生物分子相对于电极和样品是可移动的。 还公开了检测生物分子的方法。

    FET-BASED SENSOR FOR DETECTING IONIC MATERIAL, IONIC MATERIAL DETECTING DEVICE USING THE FET-BASED SENSOR, AND METHOD OF DETECTING IONIC MATERIAL USING THE FET-BASED SENSOR
    4.
    发明申请
    FET-BASED SENSOR FOR DETECTING IONIC MATERIAL, IONIC MATERIAL DETECTING DEVICE USING THE FET-BASED SENSOR, AND METHOD OF DETECTING IONIC MATERIAL USING THE FET-BASED SENSOR 有权
    用于检测离子材料的基于FET的传感器，使用基于FET的传感器的离子材料检测装置以及使用基于FET的传感器检测离子材料的方法

    公开(公告)号：US20110043213A1

    公开(公告)日：2011-02-24

    申请号：US12912191

    申请日：2010-10-26

    申请人： Kyu-sang LEE ,  Kyu-tae YOO ,  Jeo-young SHIM ,  Jin-tae KIM ,  Yeon-ja CHO

    发明人： Kyu-sang LEE ,  Kyu-tae YOO ,  Jeo-young SHIM ,  Jin-tae KIM ,  Yeon-ja CHO

    IPC分类号： G01N27/62

    CPC分类号： G01N33/54373 ,  C12Q1/6825 ,  G01N27/4145

    摘要： Provided are a FET-based sensor for detecting an ionic material, an ionic material detecting device including the FET-based sensor, and a method of detecting an ionic material using the FET-based sensor. The FET-based sensor includes: a sensing chamber including a reference electrode and a plurality of sensing FETs; and a reference chamber including a reference electrode and a plurality of reference FETs. The method includes: flowing a first solution into and out of the sensing chamber and the reference chamber of the FET-based sensor; flowing a second solution expected to contain an ionic material into and out of the sensing chamber while continuously flowing the first solution into and out of the reference chamber; measuring a current in a channel region between the source and drain of each of the sensing and reference FETs; and correcting the current of the sensing FETs.

    摘要翻译： 提供了一种用于检测离子材料的基于FET的传感器，包括基于FET的传感器的离子材料检测装置，以及使用基于FET的传感器检测离子材料的方法。 基于FET的传感器包括：感测室，包括参考电极和多个感测FET; 以及包括参考电极和多个参考FET的参考室。 该方法包括：使第一溶液流入和流出基于FET的传感器的感测室和参考室; 使预期含有离子材料的第二溶液流入和流出感测室，同时使第一溶液持续流入和移出参考室; 测量每个感测和参考FET的源极和漏极之间的沟道区域中的电流; 并校正感测FET的电流。

    Sensing switch and detecting method using the same
    7.
    发明授权
    Sensing switch and detecting method using the same 失效
    感应开关及使用其的检测方法

    公开(公告)号：US07510865B2

    公开(公告)日：2009-03-31

    申请号：US11347185

    申请日：2006-02-03

    申请人： Kyu-tae Yoo ,  Joon-ho Kim ,  Jun-hong Min ,  Sung-ouk Jung ,  Ji-na Namgoong ,  Kui-hyun Kim ,  Jeo-young Shim ,  Kak Namkoong

    发明人： Kyu-tae Yoo ,  Joon-ho Kim ,  Jun-hong Min ,  Sung-ouk Jung ,  Ji-na Namgoong ,  Kui-hyun Kim ,  Jeo-young Shim ,  Kak Namkoong

    IPC分类号： C12M1/34

    CPC分类号： G01N33/54373

    摘要： Provided are a sensing switch and a sensing method using the same. The sensing switch includes: a substrate; a supporter on the substrate; a sensing plate that is connected to a side of the supporter and is in parallel with the substrate by a predetermined distance; a receptor binding region on an upper surface of an end portion of the sensing plate; an electric or magnetic field generation device that induces deflection of the sensing plate when a receptor bound to the receptor binding region is selectively bound to an electrically or magnetically active ligand; and a pair of switching electrodes that are separated by a predetermined distance and is connected when the sensing plate contacts the substrate due to the deflection of the sensing plate. A target material need not be labelled, a signal processing of a fluorescent or electrical detection signal using an analysis apparatus is not required, and a signal can be directly decoded by confirming whether a current flows through the switch.

    摘要翻译： 提供了一种感测开关和使用该感测开关的感测方法。 感测开关包括：基板; 底物上的支撑物; 感测板，其与所述支撑体的一侧连接并且与所述基板平行预定距离; 在感测板的端部的上表面上的受体结合区域; 当与受体结合区结合的受体选择性地结合到电或磁性活性配体时，引起感测板偏转的电场或磁场产生装置; 以及一对分离预定距离的开关电极，并且当感测板由于感测板的偏转而与基板接触时被连接。 目标材料不需要标注，不需要使用分析装置的荧光或电检测信号的信号处理，并且可以通过确认电流是否流过开关直接解码信号。