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25 条记录 (耗时 0.039 秒)

    Soft capsule of butylphthalide and a process for preparing the same
    1.
    发明授权
    Soft capsule of butylphthalide and a process for preparing the same 有权
    丁基苯酞的软胶囊及其制备方法

    公开(公告)号：US08609137B2

    公开(公告)日：2013-12-17

    申请号：US13092610

    申请日：2011-04-22

    申请人： Jianqing Li ,  Min Bai ,  Wenmin Guo ,  Surui Chen ,  Liyun Liu ,  Guirong Zhou

    发明人： Jianqing Li ,  Min Bai ,  Wenmin Guo ,  Surui Chen ,  Liyun Liu ,  Guirong Zhou

    IPC分类号： A61K9/48

    CPC分类号： A61K9/4825 ,  A61K9/4816 ,  A61K9/4875 ,  A61K31/34 ,  A61K31/365

    摘要： The present invention discloses a novel soft capsule of butylphthalide and a process for preparing the same. The soft capsule of butylphthalide is composed of a capsule wall material and a drug-containing oil, wherein the drug-containing oil is essentially composed of butylphthalide and a vegetable oil as the diluent in a weight ratio of about 1:0˜10. The capsule wall material is composed of a capsule wall matrix, a plasticizer and water in a weight ratio of 1:0.2˜0.4:0.8˜1.3. The soft capsule of butylphthalide described in the present invention can mask the strong and special flavor of butylphthalide, and overcome the difficulties associated with formulating oily active ingredient into other oral formulation. The disintegration time of the soft capsule satisfies the requirement of Pharmacopoeia of P.R. China.

    摘要翻译： 本发明公开了一种丁基苯酞的新型软胶囊及其制备方法。 丁基苯酞的软胶囊由胶囊壁材料和药物含油组成，其中药物含油基本上由丁基苯酞和作为稀释剂的植物油组成，重量比为约1:0〜10。 胶囊壁材料由胶囊壁基质，增塑剂和水组成，重量比为1:0.2〜0.4:0.8〜1.3。 本发明中描述的丁基苯酞的软胶囊可以掩蔽丁苯酞的强烈和特殊风味，并克服与将油性活性成分配制成其它口服制剂相关的困难。 软胶囊的分解时间满足中国药典的药典要求。

    Butylphtualide Soft Gel Capsule and Its Preperation Procedure
    3.
    发明申请
    Butylphtualide Soft Gel Capsule and Its Preperation Procedure 审中-公开
    丁苯甲酸软胶囊及其制备方法

    公开(公告)号：US20080020034A1

    公开(公告)日：2008-01-24

    申请号：US10581370

    申请日：2004-12-03

    申请人： Jianqing Li ,  Min Bai ,  Wenmin Guo ,  Surui Chen ,  Liyun Liu ,  Guirong Zhou

    发明人： Jianqing Li ,  Min Bai ,  Wenmin Guo ,  Surui Chen ,  Liyun Liu ,  Guirong Zhou

    IPC分类号： A61K9/48 ,  A61K31/34

    CPC分类号： A61K9/4825 ,  A61K9/4816 ,  A61K9/4875 ,  A61K31/34 ,  A61K31/365

    摘要： The present invention discloses a novel dosage form of butylphthalide soft capsule and its preparation procedure. Butylphthalide soft capsule is composed of a coating material and a drug-containing oil. The drug-containing oil is basically composed of butylphthalide and diluent—vegetable oil, wherein the weight ratio of butylphthalide to oil ranges from 1:0-10. The coating material is composed of gelatin, plasticizer and water, wherein the weight ratio of gelatin to plasticizer to water is in the range of 1:0.2{tilde over ( )}0.4:0.8{tilde over ( )}0.3. The butylphthalide soft capsule described in this invention can mask the strong and specific flavor of butylphthalide, and overcome the difficulties associated with formulating oily active agents into other oral preparations. The disintegration time of the soft capsule complies with the requirement of Pharmacopoeia of P.R. China.

    摘要翻译： 本发明公开了一种丁基苯酞软胶囊的新型剂型及其制备方法。 丁苯酞软胶囊由涂料和含药油组成。 含药油基本上由丁基苯酞和稀释剂 - 植物油组成，其中丁苯酞与油的重量比为1:0-10。 涂料由明胶，增塑剂和水组成，其中明胶与增塑剂与水的重量比在1：0.20.4：0.80.3的范围内。 本发明中描述的丁基苯酞软胶囊可以掩蔽丁苯酞的强烈和特异的风味，并克服与将油性活性剂配制成其它口服制剂相关的困难。 软胶囊的分解时间符合中国药典的药典要求。

    S-6-hydroxy-buspirone
    4.
    发明授权
    S-6-hydroxy-buspirone 失效
    S-6-羟基丁螺环酮

    公开(公告)号：US06821976B2

    公开(公告)日：2004-11-23

    申请号：US10201063

    申请日：2002-07-22

    申请人： Joseph P. Yevich ,  Robert F. Mayol ,  Jianqing Li ,  Frank Yocca

    发明人： Joseph P. Yevich ,  Robert F. Mayol ,  Jianqing Li ,  Frank Yocca

    IPC分类号： A61K31506

    CPC分类号： C07D401/12 ,  A61K31/506

    摘要： The S-stereoisomer of 6-hydroxy-buspirone is an effective treatment for anxiety, depression, and other psychogenic disorders. The S-isomer may provide reduced potential for adverse effects and a longer duration of action compared to the racemic mixture and with buspirone.

    摘要翻译： 6-羟基丁螺环酮的S-立体异构体是焦虑，抑郁和其他心理疾病的有效治疗方法。 与外消旋混合物和丁螺环酮相比，S-异构体可以提供减少的副作用潜力和较长的作用时间。

    Soft capsule of butylphthalide and a process for preparing the same
    7.
    发明申请
    Soft capsule of butylphthalide and a process for preparing the same 有权
    丁基苯酞的软胶囊及其制备方法

    公开(公告)号：US20120052117A1

    公开(公告)日：2012-03-01

    申请号：US13092610

    申请日：2011-04-22

    申请人： Jianqing Li ,  Min Bai ,  Wenmin Guo ,  Surui Chen ,  Liyun Liu ,  Guirong Zhou

    发明人： Jianqing Li ,  Min Bai ,  Wenmin Guo ,  Surui Chen ,  Liyun Liu ,  Guirong Zhou

    IPC分类号： A61K9/48 ,  A61K31/05

    CPC分类号： A61K9/4825 ,  A61K9/4816 ,  A61K9/4875 ,  A61K31/34 ,  A61K31/365

    摘要： The present invention discloses a novel soft capsule of butylphthalide and a process for preparing the same. The soft capsule of butylphthalide is composed of a capsule wall material and a drug-containing oil, wherein the drug-containing oil is essentially composed of butylphthalide and a vegetable oil as the diluent in a weight ratio of about 1:0˜10. The capsule wall material is composed of a capsule wall matrix, a plasticizer and water in a weight ratio of 1:0.2˜0.4:0.8˜1.3. The soft capsule of butylphthalide described in the present invention can mask the strong and special flavour of butylphthalide, and overcome the difficulties associated with formulating oily active ingredient into other oral formulation. The disintegration time of the soft capsule satisfies the requirement of Pharmacopoeia of P.R. China.

    摘要翻译： 本发明公开了一种丁基苯酞的新型软胶囊及其制备方法。 丁基苯酞的软胶囊由胶囊壁材料和药物含油组成，其中含药油基本上由丁基苯酞和植物油作为稀释剂组成，重量比为约1:0〜10。 胶囊壁材料由胶囊壁基质，增塑剂和水组成，重量比为1:0.2〜0.4：0.8〜1.3。 本发明中描述的丁基苯酞的软胶囊可以掩蔽丁苯酞的强烈和特殊风味，并克服与将油性活性成分配制成其它口服制剂相关的困难。 软胶囊的分解时间满足中国药典的药典要求。

    Heavy metal chelate composition containing chitosan derivatives and uses thereof
    10.
    发明申请
    Heavy metal chelate composition containing chitosan derivatives and uses thereof 审中-公开
    含有壳聚糖衍生物的重金属螯合物组合物及其用途

    公开(公告)号：US20060151396A1

    公开(公告)日：2006-07-13

    申请号：US10522631

    申请日：2003-07-23

    申请人： Qisheng Ren ,  Xinrong Song ,  Jianqing Li ,  Rui Ma ,  Zongfu Mei ,  Xinyun Ma

    发明人： Qisheng Ren ,  Xinrong Song ,  Jianqing Li ,  Rui Ma ,  Zongfu Mei ,  Xinyun Ma

    IPC分类号： C02F1/42

    CPC分类号： C08L5/08 ,  B09B3/00 ,  B09C1/02 ,  C02F1/683 ,  C02F2101/20 ,  C08B37/003 ,  C08L79/02 ,  C08L2666/20 ,  C08L2666/26

    摘要： This patent provides a kind of chelator compound of heavy metals containing chitosan (CTS) derivatives, which contains the following contents: ComponentsContent WT % Containing at least one dithio-formate1-100 (dithiocarbamate) CTS derivatives Containing at least one dithio-formate0-99  (dithiocarbamate) polyamine derivatives This chelator compound of heavy metals is suitable for the treatment of the wastewater, waste mud, and garbage burned ash that contains heavy metals, or the soil polluted by heavy metal ions.

    摘要翻译： 该专利提供了一种含有壳聚糖（CTS）衍生物的重金属螯合剂化合物，其含有以下内容：

    < ENTRY /> < ENTRY>组件 内容WT％ 至少包含一个二硫化碳 1-100 / ROW> （二硫代氨基甲酸盐）CTS衍生物 包含至少一个二硫代甲酸酯 0 -99 （二硫代氨基甲酸盐）多胺衍生物 重金属螯合剂化合物适用于废水，废物 泥土和含有重金属的垃圾灰，或被重金属离子污染的土壤。