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公开(公告)号:US20110256154A1
公开(公告)日:2011-10-20
申请号:US13082852
申请日:2011-04-08
申请人: Sylvie Vincent , William M. Winston, JR. , Fang Wang , Solly Weiler , Kristan Meetze , Lyne Breault , Steve Botega , Ting Chen , Michael DePrima , Christina Fleet , Steven Tyler , Jin-Kyeung Woo , Jeno Gyuris
发明人: Sylvie Vincent , William M. Winston, JR. , Fang Wang , Solly Weiler , Kristan Meetze , Lyne Breault , Steve Botega , Ting Chen , Michael DePrima , Christina Fleet , Steven Tyler , Jin-Kyeung Woo , Jeno Gyuris
IPC分类号: A61K39/395 , C07H21/00 , C12P21/00 , C12N15/63 , C12N1/00 , C12N5/10 , C07K16/28 , A61P35/00
CPC分类号: C07K16/32 , A61K39/39558 , A61K2039/505 , C07K16/30 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要: Monoclonal antibodies that bind and inhibit activation of epidermal growth factor receptor related member ErbB3/HER3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of ErbB3/HER3.
摘要翻译: 公开了结合并抑制表皮生长因子受体相关成分ErbB3 / HER3活化的单克隆抗体。 抗体可用于治疗与ErbB3 / HER3的激活相关的细胞增殖性疾病和病症,包括某些形式的癌症。
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公开(公告)号:US08481687B2
公开(公告)日:2013-07-09
申请号:US13082852
申请日:2011-04-08
申请人: Sylvie Vincent , William M. Winston, Jr. , Fang Wang , Solly Weiler , Kristan Meetze , Lyne Breault , Steve Bottega , Ting Chen , Michael DePrima , Christina Fleet , Steven Tyler , Jin-Kyeung Woo , Jeno Gyuris
发明人: Sylvie Vincent , William M. Winston, Jr. , Fang Wang , Solly Weiler , Kristan Meetze , Lyne Breault , Steve Bottega , Ting Chen , Michael DePrima , Christina Fleet , Steven Tyler , Jin-Kyeung Woo , Jeno Gyuris
IPC分类号: C07K16/28
CPC分类号: C07K16/32 , A61K39/39558 , A61K2039/505 , C07K16/30 , C07K2317/24 , C07K2317/51 , C07K2317/515 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要: Monoclonal antibodies that bind and inhibit activation of epidermal growth factor receptor related member ErbB3/HER3 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of ErbB3/HER3.
摘要翻译: 公开了结合并抑制表皮生长因子受体相关成分ErbB3 / HER3活化的单克隆抗体。 抗体可用于治疗与ErbB3 / HER3的激活相关的细胞增殖性疾病和病症,包括某些形式的癌症。
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