公开(公告)号：US20130037726A1

公开(公告)日：2013-02-14

申请号：US13206436

申请日：2011-08-09

申请人： Peter Kiesel ,  Joerg Martini

发明人： Peter Kiesel ,  Joerg Martini

IPC分类号： G01N21/64 ,  G01J3/443

CPC分类号： G01J3/36 ,  G01J2003/104 ,  G01N15/1459 ,  G01N21/05 ,  G01N21/6428 ,  G01N21/65 ,  G01N2015/1006 ,  G01N2015/145 ,  G01N2021/6419 ,  G01N2201/0691

摘要： A compact analyzer includes a flow cell having a flow channel through which a sample is made to pass. First and second light sources are arranged to emit first and second excitation light into first and second overlapping portions of the flow channel, respectively. The first excitation light stimulates a first light emission from particles of a first particle type that may be present in the sample; the second excitation light stimulates a second light emission from particles of a second particle type. A detector receives the first and second light emission from the corresponding particles present in the sample in a detection portion of the flow channel, and provides a detector output based on the received light emission. The light sources are modulated at different frequencies so that a frequency analysis of the detector output can provide separate information about the first and second particle types.

摘要翻译： 紧凑型分析器包括具有流通通道的流通池，样品通过该流路通过。 第一和第二光源分别布置成将第一和第二激发光发射到流动通道的第一和第二重叠部分。 第一激发光刺激可能存在于样品中的第一颗粒类型的颗粒的第一光发射; 第二激发光刺激来自第二粒子类型的颗粒的第二光发射。 检测器在流动通道的检测部分中接收来自样品中存在的相应颗粒的第一和第二光发射，并且基于接收到的光发射提供检测器输出。 光源以不同的频率被调制，使得检测器输出的频率分析可以提供关于第一和第二粒子类型的单独的信息。

公开(公告)号：US08153950B2

公开(公告)日：2012-04-10

申请号：US12337771

申请日：2008-12-18

申请人： Peter Kiesel ,  Markus Beck ,  Joerg Martini ,  Michael Bassler ,  Noble M. Johnson

发明人： Peter Kiesel ,  Markus Beck ,  Joerg Martini ,  Michael Bassler ,  Noble M. Johnson

IPC分类号： G01J1/42 ,  F21V9/16 ,  G01N21/25

CPC分类号： G01J3/2803 ,  G01J3/02 ,  G01J3/027 ,  G01N15/12 ,  G01N15/1429 ,  G01N15/1459 ,  G01N2015/1075 ,  G01N2021/1734

摘要： An encoder/sensor can obtain sensing results from objects in an encoding/sensing region; a trigger detector can respond to objects in a trigger detection region, providing respective trigger signals; and a relative motion component can cause relative motion of objects into the trigger detection region, from it into the encoding/sensing region, and within the encoding/sensing region. In response to an object's trigger signal, control circuitry can cause the encoder/sensor and/or the relative motion component to operate so that the encoder/sensor obtains sensing results indicating a time-varying waveform and processing circuitry can obtain data from the sensing results indicating a time-varying waveform. The time-varying waveform can include information resulting from the relative motion within the encoding/sensing region. The encoder/sensor and trigger detector can be implemented, for example, with discrete components or as sets of cells in a photosensing array on an integrated circuit.

摘要翻译： 编码器/传感器可以从编码/感测区域中的对象获得感测结果; 触发检测器可以响应触发检测区域中的对象，提供相应的触发信号; 并且相对运动分量可以引起物体进入触发检测区域的相对运动，从而进入编码/感测区域，并且在编码/感测区域内。 响应于物体的触发信号，控制电路可以使编码器/传感器和/或相对运动分量运行，使得编码器/传感器获得指示时变波形的感测结果，并且处理电路可以从感测结果获得数据 表示时变波形。 时变波形可以包括由编码/感测区域内的相对运动产生的信息。 编码器/传感器和触发检测器可以例如利用集成电路中的光敏阵列中的分立组件或单元组来实现。

公开(公告)号：US07961326B2

公开(公告)日：2011-06-14

申请号：US12195997

申请日：2008-08-21

申请人： Joerg Martini ,  Richard H. Bruce ,  Francisco E. Torres ,  Peter Kiesel ,  Michael I. Recht ,  Jeffrey N. Roe

发明人： Joerg Martini ,  Richard H. Bruce ,  Francisco E. Torres ,  Peter Kiesel ,  Michael I. Recht ,  Jeffrey N. Roe

IPC分类号： A61B5/00 ,  G01J3/46

CPC分类号： A61B5/1459 ,  A61B5/0031 ,  A61B5/14532 ,  G01N21/33 ,  G01N21/359

摘要： A system and method is provided for detecting concentration of an analyte in a fluid. The method comprises detecting an optical property of a first region of two or more regions in a system, the first region located in a container having a reservoir for one or more modifiers of one or more optical properties of the first region. The movement of the one or more modifiers is responsive to changes in concentration of the analyte. A next step detects an optical property of a second region of the two or more regions in the system, the second region located in a container having a reservoir for one or more modifiers of one or more optical properties of the second region. The movement of the one or more modifiers is responsive to changes in concentration of a compound, where the compound is something other than the analyte. The detected optical property of the first region and the detected optical property of the second region are used in embodiments to separate the effect of the analyte on the detected optical property of the first region from the effect of the compound, where the compound is an interfering compound.

摘要翻译： 提供了用于检测流体中分析物的浓度的系统和方法。 该方法包括检测系统中两个或更多个区域的第一区域的光学性质，位于容器中的第一区域具有用于一个或多个第一区域的一个或多个光学特性的改性剂的储存器。 一种或多种改性剂的运动响应于分析物浓度的变化。 下一步骤检测系统中两个或更多个区域的第二区域的光学性质，位于容器中的第二区域具有用于一个或多个第二区域的一个或多个光学特性的改性剂的储存器。 一种或多种改性剂的运动响应化合物浓度的变化，其中化合物是除分析物以外的物质。 检测到的第一区域的光学特性和第二区域的检测光学特性用于实施例中以将分析物对第一区域的检测光学性质的影响与化合物的影响分开，其中化合物是干扰 复合。

公开(公告)号：US20070075567A1

公开(公告)日：2007-04-05

申请号：US11523179

申请日：2006-09-19

申请人： Juergen Hoppen ,  Joerg Martini ,  Gerald Richter

发明人： Juergen Hoppen ,  Joerg Martini ,  Gerald Richter

IPC分类号： B62D25/08

CPC分类号： B62D25/145 ,  B60H1/00535

摘要： The invention relates to a load-carrying component that makes it possible to support a vehicle cross-member or module carrier on the floor region of the body of a motor vehicle. The load-carrying component serves to attach an air conditioning unit and is connected to as least one casing part of the air conditioning unit such that the load-carrying component and the casing create at least one channel through which conditioned air flows into the passenger compartment of the vehicle.

摘要翻译： 本发明涉及一种承载部件，其使得可以在机动车辆的车体的地板区域上支撑车辆横梁或模块托架。 负载部件用于安装空调单元并且连接到空调单元的至少一个壳体部分，使得承载部件和壳体产生至少一个通道，调节空气通过该通道流入乘客室 的车辆。

公开(公告)号：US09161714B2

公开(公告)日：2015-10-20

申请号：US12195942

申请日：2008-08-21

申请人： Joerg Martini ,  Richard H. Bruce ,  Francisco E. Torres ,  Peter Kiesel ,  Michael I. Recht ,  Jeffrey N. Roe

发明人： Joerg Martini ,  Richard H. Bruce ,  Francisco E. Torres ,  Peter Kiesel ,  Michael I. Recht ,  Jeffrey N. Roe

IPC分类号： A61B5/00 ,  A61B5/1459 ,  A61B5/145 ,  G01N21/33 ,  G01N21/359

CPC分类号： A61B5/1459 ,  A61B5/0031 ,  A61B5/14532 ,  G01N21/33 ,  G01N21/359

摘要： A system and method is provided for detecting concentration of an analyte in a fluid. A first container includes (i) an optical cavity detection region, (ii) a reservoir for one or more modifiers of one or more optical properties of the optical cavity detection region, and (iii) a set of one or more bounding regions through which objects in the fluid can transfer into the container. The optical cavity detection region and the reservoir define separate areas of the first container. The movement of the one or more modifiers between the reservoir and the optical cavity detection region is responsive to changes in concentration of the analyte. A second container includes an optical cavity detection region, and a set of one or more bounding regions through which objects in the fluid can transfer into the container. Also provided are optical components for guiding light into the optical cavity detection regions of the first and second containers.

摘要翻译： 提供了用于检测流体中分析物的浓度的系统和方法。 第一容器包括（i）光腔检测区域，（ii）用于一个或多个光腔检测区域的一个或多个光学特性的修改器的储存器，以及（iii）一组或多个边界区域， 流体中的物体可以转移到容器中。 光腔检测区域和储存器限定第一容器的分开的区域。 储存器和光腔检测区域之间的一个或多个改性剂的运动响应于分析物浓度的变化。 第二容器包括光学腔检测区域和一组一个或多个界限区域，流体中的物体可通过该区域传送到容器中。 还提供了用于将光引导到第一和第二容器的光学腔检测区域中的光学部件。

公开(公告)号：US20130153771A1

公开(公告)日：2013-06-20

申请号：US13328800

申请日：2011-12-16

申请人： Peter Kiesel ,  Marshall W. Bern ,  Joerg Martini ,  Malte Huck

发明人： Peter Kiesel ,  Marshall W. Bern ,  Joerg Martini ,  Malte Huck

IPC分类号： H01L31/0232 ,  G01J1/04 ,  G01J5/08

CPC分类号： G01J1/04 ,  G01S11/12 ,  G01S17/88 ,  G08G1/015 ,  G08G1/04

摘要： Traffic monitors based on non-imaging radiation detectors are described. A traffic monitor includes a non-imaging radiation detector that senses spatially patterned radiation emanating from objects moving in a traffic pattern. The detector generates a time varying output signal based on the sensed radiation. Signal processing circuitry is used to analyze the time varying output signal using time domain analysis to provide the traffic information.

摘要翻译： 描述了基于非成像辐射探测器的交通监视器。 交通监控器包括非成像辐射检测器，其感测从以交通模式移动的物体发出的空间图案化辐射。 检测器基于感测的辐射产生时变输出信号。 信号处理电路用于分析时变输出信号，使用时域分析提供交通信息。

公开(公告)号：US08153949B2

公开(公告)日：2012-04-10

申请号：US12337737

申请日：2008-12-18

申请人： Peter Kiesel ,  Joerg Martini ,  Michael Bassler ,  Markus Beck ,  Noble M. Johnson

发明人： Peter Kiesel ,  Joerg Martini ,  Michael Bassler ,  Markus Beck ,  Noble M. Johnson

IPC分类号： G01J1/42 ,  F21V9/16 ,  G01N21/25

CPC分类号： G01N15/1429 ,  G01N15/1056 ,  G01N15/12 ,  G01N15/1459 ,  G01N2015/1006 ,  G01N2015/1037 ,  G01N2015/1075

摘要： In response to objects having relative motion within an encoding/sensing region relative to an encoder/sensor that, e.g., photosenses emanating light or performs impedance-based sensing, sensing results can indicate sensed time-varying waveforms with information about the objects, about their relative motion, about excitation characteristics, about environmental characteristics, and so forth. An encoder/sensor can include, for example, a non-periodic arrangement of sensing elements; a longitudinal sequence of sensing elements with a combined sensing pattern that approximates a superposition or scaled superposition of simpler sensing patterns; and/or IC-implemented sensing elements that include photosensing arrays on ICs and readout/combine circuitry that reads out photosensed quantities from cells in groups in accordance with cell-group sensing patterns and combines the readout photosensed quantities to obtain the sensing results. Objects can move fluidically as in flow cytometry, through scanning movement as in document scanning, or in other ways.

摘要翻译： 响应于相对于编码器/传感器在编码/感测区域内具有相对运动的物体，例如，发出光的光照或执行基于阻抗的感测，感测结果可以指示感测到的具有关于物体的信息的时变波形，关于它们 相对运动，关于激发特性，关于环境特性等。 编码器/传感器可以包括例如感测元件的非周期性布置; 具有组合感测图案的感测元件的纵向序列，其近似于更简单的感测图案的叠加或缩放叠加; 和/或IC实现的感测元件，其包括IC上的光敏阵列和读出/组合电路，其根据单元组感测图案从组中的单元读出光照量，并组合读出的光照量以获得感测结果。 物体可以像流式细胞仪一样流动地进行扫描运动，如文档扫描或其他方式。

公开(公告)号：US20100185143A1

公开(公告)日：2010-07-22

申请号：US12356824

申请日：2009-01-21

申请人： Scott Albert Uhland ,  Eric Peeters ,  Bryan Thomas Preas ,  Joerg Martini

发明人： Scott Albert Uhland ,  Eric Peeters ,  Bryan Thomas Preas ,  Joerg Martini

IPC分类号： A61M31/00

CPC分类号： A61M5/1723 ,  A61M5/16836 ,  A61M5/1684 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3317 ,  A61M2205/3368

摘要： A system for use with a drug delivery device includes a sensor unit and a deactivation unit operatively coupled to an output of the sensor unit and to a drug-retaining region of the drug delivery device, wherein the drug-retaining region contains a drug. The sensor unit is configured to detect a characteristic of a local environment and generate an output corresponding to a value of the detected characteristic. The deactivation unit is configured to render the drug ineffective when the output of the sensor unit satisfies a predetermined condition.

摘要翻译： 用于药物递送装置的系统包括传感器单元和可操作地耦合到传感器单元的输出和药物递送装置的药物保持区域的停用单元，其中药物保持区域包含药物。 传感器单元被配置为检测局部环境的特性并产生对应于检测到的特性的值的输出。 所述停用单元被配置为当所述传感器单元的输出满足预定条件时使所述药物无效。

公开(公告)号：US09480795B2

公开(公告)日：2016-11-01

申请号：US12356824

申请日：2009-01-21

申请人： Scott Albert Uhland ,  Eric Peeters ,  Bryan Thomas Preas ,  Joerg Martini

发明人： Scott Albert Uhland ,  Eric Peeters ,  Bryan Thomas Preas ,  Joerg Martini

IPC分类号： A61M5/172 ,  A61M5/168

CPC分类号： A61M5/1723 ,  A61M5/16836 ,  A61M5/1684 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3317 ,  A61M2205/3368

摘要： A system for use with a drug delivery device includes a sensor unit and a deactivation unit operatively coupled to an output of the sensor unit and to a drug-retaining region of the drug delivery device, wherein the drug-retaining region contains a drug. The sensor unit is configured to detect a characteristic of a local environment and generate an output corresponding to a value of the detected characteristic. The deactivation unit is configured to render the drug ineffective when the output of the sensor unit satisfies a predetermined condition.

摘要翻译： 用于药物递送装置的系统包括传感器单元和可操作地耦合到传感器单元的输出和药物递送装置的药物保持区域的停用单元，其中药物保持区域包含药物。 传感器单元被配置为检测局部环境的特性并产生对应于检测到的特性的值的输出。 所述停用单元被配置为当所述传感器单元的输出满足预定条件时使所述药物无效。

公开(公告)号：US08963092B2

公开(公告)日：2015-02-24

申请号：US13328800

申请日：2011-12-16

申请人： Peter Kiesel ,  Marshall W. Bern ,  Joerg Martini ,  Malte Huck

发明人： Peter Kiesel ,  Marshall W. Bern ,  Joerg Martini ,  Malte Huck

IPC分类号： G01J1/04

CPC分类号： G01J1/04 ,  G01S11/12 ,  G01S17/88 ,  G08G1/015 ,  G08G1/04

摘要： Traffic monitors based on non-imaging radiation detectors are described. A traffic monitor includes a non-imaging radiation detector that senses spatially patterned radiation emanating from objects moving in a traffic pattern. The detector generates a time varying output signal based on the sensed radiation. Signal processing circuitry is used to analyze the time varying output signal using time domain analysis to provide the traffic information.

摘要翻译： 描述了基于非成像辐射探测器的交通监视器。 交通监控器包括非成像辐射检测器，其感测从以交通模式移动的物体发出的空间图案化辐射。 检测器基于感测的辐射产生时变输出信号。 信号处理电路用于分析时变输出信号，使用时域分析提供交通信息。