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公开(公告)号:US08807164B2
公开(公告)日:2014-08-19
申请号:US11847971
申请日:2007-08-30
申请人: Joerg Werner Baier , Robert Charles Mierendorf , Anthony Charles Grabski , Andrew Paul Wilke , Anil Rajaram Oroskar
发明人: Joerg Werner Baier , Robert Charles Mierendorf , Anthony Charles Grabski , Andrew Paul Wilke , Anil Rajaram Oroskar
IPC分类号: F16K11/10
CPC分类号: G01N30/44 , B01D15/1821 , B01D15/1842 , B01D15/3804 , G01N30/20 , G01N2030/202 , Y10T137/86509 , Y10T137/86533 , Y10T137/86549 , Y10T137/8667 , Y10T137/87249 , Y10T137/87885
摘要: The present invention provides devices and methods for micro-scale simulated moving bed chromatography (SMB) for continuous preparation of analytic quantities of highly pure fractions of target molecules. The present apparatus and method of the invention is adapted in a preferred embodiment to separations by affinity chromatography involving three discontinuous liquid flow loops. An alternative embodiment of affinity chromatography utilizes standard SMB operating under isocratic conditions.
摘要翻译: 本发明提供用于连续制备分析量高的目标分子的高纯度级分的微尺度模拟移动床层析(SMB)的装置和方法。 本发明的本发明的装置和方法在优选实施方案中适用于通过亲和层析分离,涉及三个不连续的液体流动循环。 亲和层析的另一个实施方案利用在等度条件下操作的标准SMB。
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公开(公告)号:US07849738B2
公开(公告)日:2010-12-14
申请号:US11716097
申请日:2007-03-09
IPC分类号: G01F23/28
CPC分类号: B01L3/0268 , B01L2200/143 , G01N35/1011
摘要: A device and method for the detection of the interaction between two or more objects is disclosed. The device utilizes electrical impedance spectra measured from a piezoelectric element attached to one such object. Comparison of such spectra along a range of traverse allows precise estimates of distance to be made. One useful application is the topographical mapping of a surface.
摘要翻译: 公开了一种用于检测两个或多个物体之间的相互作用的装置和方法。 该器件利用从连接到一个这样的对象的压电元件测量的电阻抗谱。 沿着横越范围的这种光谱的比较允许精确估计距离。 一个有用的应用是表面的地形图。
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公开(公告)号:US07790040B2
公开(公告)日:2010-09-07
申请号:US11847983
申请日:2007-08-30
申请人: Robert Charles Mierendorf , Herbert Edmund Paaren , Anthony Charles Grabski , Andrew Wilke , Joerg Werner Baier , Anil Rajaram Oroskar
发明人: Robert Charles Mierendorf , Herbert Edmund Paaren , Anthony Charles Grabski , Andrew Wilke , Joerg Werner Baier , Anil Rajaram Oroskar
IPC分类号: B01D15/08
CPC分类号: F16K11/022 , B01D15/1842 , B01D15/3804 , Y10T137/86533 , Y10T137/86654
摘要: The present invention provides devices and methods for micro-scale simulated moving bed chromatography (SMB) for continuous preparation of analytic quantities of highly pure fractions of target molecules. The present apparatus and method of the invention is adapted in a preferred embodiment to separations by affinity chromatography involving three discontinuous liquid flow loops. An alternative embodiment of affinity chromatography utilizes standard SMB operating under isocratic conditions.
摘要翻译: 本发明提供用于连续制备分析量高的目标分子的高纯度级分的微尺度模拟移动床层析(SMB)的装置和方法。 本发明的本发明的装置和方法在优选实施方案中适用于通过亲和层析分离,涉及三个不连续的液体流动循环。 亲和层析的另一个实施方案利用在等度条件下操作的标准SMB。
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公开(公告)号:US20070210677A1
公开(公告)日:2007-09-13
申请号:US11716097
申请日:2007-03-09
IPC分类号: H01L41/113
CPC分类号: B01L3/0268 , B01L2200/143 , G01N35/1011
摘要: A device and method for the detection of the interaction between two or more objects is disclosed. The device utilizes electrical impedance spectra measured from a piezoelectric element attached to one such object. Comparison of such spectra along a range of traverse allows precise estimates of distance to be made. One useful application is the topographical mapping of a surface.
摘要翻译: 公开了一种用于检测两个或多个物体之间的相互作用的装置和方法。 该器件利用从连接到一个这样的对象的压电元件测量的电阻抗谱。 沿着横越范围的这种光谱的比较允许精确估计距离。 一个有用的应用是表面的地形图。
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公开(公告)号:US20110095651A1
公开(公告)日:2011-04-28
申请号:US12913470
申请日:2010-10-27
IPC分类号: G01H11/08
CPC分类号: B01L3/0268 , B01L2200/143 , G01N35/1011
摘要: A device and method for the detection of the interaction between two or more objects is disclosed. The device utilizes electrical impedance spectra measured from a piezoelectric element attached to one such object. Comparison of such spectra along a range of traverse allows precise estimates of distance to be made. One useful application is the topographical mapping of a surface.
摘要翻译: 公开了一种用于检测两个或多个物体之间的相互作用的装置和方法。 该器件利用从连接到一个这样的对象的压电元件测量的电阻抗谱。 沿着横越范围的这种光谱的比较允许精确估计距离。 一个有用的应用是表面的地形图。
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