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公开(公告)号:US20200237817A1
公开(公告)日:2020-07-30
申请号:US16774425
申请日:2020-01-28
IPC分类号: A61K35/14 , A61K38/21 , C12N5/0783 , A61P35/02
摘要: Among the various aspects of the present disclosure is the provision of methods and compositions for upregulating MHC class II in cancer cells (e.g., a hematological cancer cell). Also provided are methods of treatment for subjects suffering from hematological cancers, comprising administration of interferon-γ (IFN-γ). The methods of treatment provided herein may be particularly suitable for subjects who have received an allogenic transplant or have suffered a relapse.