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公开(公告)号：US20130145688A1
公开(公告)日：2013-06-13
申请号：US13701416
申请日：2011-04-19
Applicant: Naoyuki Tatsumi , Hiroshi Fuji , Fumiteru Akamatsu , Akio Kobayashi , Shuji Kurimoto , Yoshito Suda , Kazuhito Fujiyama , Atsushi Okazawa , Kazumasa Hirata , Kazuo Harada , Takashi Machimura , Satoru Kato , Jun Hayashi
Inventor： Naoyuki Tatsumi , Hiroshi Fuji , Fumiteru Akamatsu , Akio Kobayashi , Shuji Kurimoto , Yoshito Suda , Kazuhito Fujiyama , Atsushi Okazawa , Kazumasa Hirata , Kazuo Harada , Takashi Machimura , Satoru Kato , Jun Hayashi
CPC classification number: A01G9/00 , A01G7/00 , A01G9/24 , Y02A40/264
Abstract: A plant cultivation method of the present invention includes the steps of: placing a plant under a condition at a pressure of not less than 1.5 atmospheres and not more than 10 atmospheres; and cultivating the plant. A plant cultivation device (1) includes: a cultivation chamber (10); and a compressor (20) which supplies compressed air into the cultivation chamber. A carry-in opening (30), which is provided on a side wall (16) of the cultivation chamber (10) so that a material is carried in/out to/from the cultivation chamber (10) via the carry-in opening (30), is provided with a cover (31) which has a shape that is hemispherical and protrudes toward an inside of the cultivation chamber (10). The cover (31) closes the carry-in opening (30) by being in contact, via a packing (32), with an inner surface of the side wall (16) surrounding the carry-in opening (30). The cultivation chamber (10) has an internal pressure higher than an atmospheric pressure by causing the compressor (20) to supply compressed air into the cultivation chamber (10) in a state in which the carry-in opening (30) is closed. A plant growth rate is improved by cultivating a plant in a high pressure environment which is different from a natural environment. A plant cultivation device is provided for achieving plant cultivation in a high pressure environment.
Abstract translation: 本发明的植物栽培方法包括以下步骤：将植物置于不低于1.5个大气压且不超过10个大气压的条件下; 并栽培植物。 植物栽培装置（1）包括：培养室（10）; 以及将压缩空气供给到培养室中的压缩机（20）。 一种设置在培养室（10）的侧壁（16）上的搬运开口（30），使得材料经由进入开口（10）进入/离开培养室（10） （30）设置有具有半球形状并朝向栽培室（10）的内侧突出的盖（31）。 盖31通过密封件32与侧壁（16）的内表面围绕进入开口（30）而接触地封闭进入口30。 在进入开口（30）关闭的状态下，通过使压缩机（20）将压缩空气供给至培养室（10），培养室（10）的内压高于大气压。 通过在不同于自然环境的高压环境中培育植物来改善植物生长速率。 提供植物栽培装置，用于在高压环境中实现植物栽培。
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公开(公告)号：US08241909B2
公开(公告)日：2012-08-14
申请号：US12795316
申请日：2010-06-07
Applicant: Tatsuji Seki , Kazuhito Fujiyama
Inventor： Tatsuji Seki , Kazuhito Fujiyama
CPC classification number: C12N9/0065 , C12N9/1051 , C12N15/8242 , C12N15/8245 , C12N15/8257 , C12P21/005 , C12Y111/01007 , C12Y204/01038
Abstract: The present invention provides a method for manufacturing a glycoprotein having a human-type sugar chain comprising a step in which transformed plant cell is obtained by introducing to a plant cell the gene of glycosyltransfetase and the gene of an exogenous glycoprotein, and a step in which the obtained transformed plant cell is cultivated.
Abstract translation: 本发明提供一种制造具有人型糖链的糖蛋白的方法，其包括通过向植物细胞中导入糖基转移酶的基因和外源糖蛋白的基因而获得转化的植物细胞的步骤，其中， 培养获得的转化植物细胞。
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3.发明申请Method for secretory production of glycoprotein having human-type sugar chain using plant cell 审中-公开使用植物细胞分泌生产具有人型糖链的糖蛋白的方法公开(公告)号：US20080034456A1
公开(公告)日：2008-02-07
申请号：US11717956
申请日：2007-03-14
Applicant: Kazuhito Fujiyama , Tatsuji Seki
Inventor： Kazuhito Fujiyama , Tatsuji Seki
CPC classification number: C12P21/005 , C07K14/47 , C12N9/00 , C12N9/0065 , C12N9/1051 , C12N15/8257
Abstract: A method for the secretory production of a glycoprotein having a human-type sugar chain, comprising a step of introducing a gene of an enzyme capable of performing a transfer reaction of a galactose residue to a non-reducing terminal acetylglucosamine residue, and a gene of heterologous glycoprotein, to obtain a transformed plant cell, a step of culturing the plant cell, and a step of recovering the culture medium of the plant cell.
Abstract translation: 一种用于分泌具有人型糖链的糖蛋白的方法，包括将能够进行半乳糖残基的转移反应的酶的基因导入非还原性末端乙酰葡糖胺残基的步骤，以及基因 异源糖蛋白，以获得转化的植物细胞，培养植物细胞的步骤和回收植物细胞的培养基的步骤。
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公开(公告)号：US06998267B1
公开(公告)日：2006-02-14
申请号：US09857651
申请日：1999-12-08
Applicant: Tatsuji Seki , Kazuhito Fujiyama
Inventor： Tatsuji Seki , Kazuhito Fujiyama
CPC classification number: C12N9/0065 , C12N9/1051 , C12N15/8242 , C12N15/8245 , C12N15/8257 , C12P21/005 , C12Y111/01007 , C12Y204/01038
Abstract: The present invention provides a method for manufacturing a glycoprotein having a mammalian-type or human-type sugar chain comprising a step in which a transformed plant cell is obtained by introducing to a plant cell a gene encoding a glycosyltransferase enzyme and a gene encoding an exogenous glycoprotein, and a step in which the obtained transformed plant cell is cultivated.
Abstract translation: 本发明提供一种具有哺乳动物型或人型糖链的糖蛋白的制造方法，其特征在于，包括通过向植物细胞导入编码糖基转移酶的基因和编码外源基因的基因而获得转化的植物细胞的步骤 糖蛋白，以及培养获得的转化植物细胞的步骤。
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公开(公告)号：US20050144670A1
公开(公告)日：2005-06-30
申请号：US10467101
申请日：2002-03-06
Applicant: Kazuhito Fujiyama , Tatsuji Seki , Naoyuki Taniguchi
Inventor： Kazuhito Fujiyama , Tatsuji Seki , Naoyuki Taniguchi
CPC classification number: C12N9/1051 , C12N15/8257 , C12P21/005
Abstract: A plant cell having an animal-type sugar chain adding function is provided. The plant cell has an introduced gene encoding an enzyme derived from an animal, and the enzyme can transfer a fucose residue to a reducing terminal acetylglucosamine residue of a sugar chan of a glycoprotein.
Abstract translation: 提供具有动物型糖链添加功能的植物细胞。 植物细胞具有编码来源于动物的酶的引入基因，并且该酶可以将岩藻糖残基转移到糖蛋白的糖a的还原性末端乙酰葡糖胺残基。
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Patent Agency Ranking
6.发明授权Method for secretory production of glycoprotein having human-type sugar chain using plant cell 有权使用植物细胞分泌生产具有人型糖链的糖蛋白的方法公开(公告)号：US08309795B2
公开(公告)日：2012-11-13
申请号：US12836925
申请日：2010-07-15
Applicant: Kazuhito Fujiyama , Tatsuji Seki
Inventor： Kazuhito Fujiyama , Tatsuji Seki
CPC classification number: C12P21/005 , C07K14/47 , C12N9/00 , C12N9/0065 , C12N9/1051 , C12N15/8257
Abstract: A method for the secretory production of a glycoprotein having a human-type sugar chain, comprising a step of introducing a gene of an enzyme capable of performing a transfer reaction of a galactose residue to a non-reducing terminal acetylglucosamine residue, and a gene of heterologous glycoprotein, to obtain a transformed plant cell, a step of culturing the plant cell, and a step of recovering the culture medium of the plant cell.
Abstract translation: 一种用于分泌具有人型糖链的糖蛋白的方法，包括将能够进行半乳糖残基的转移反应的酶的基因导入非还原性末端乙酰葡糖胺残基的步骤，以及基因 异源糖蛋白，以获得转化的植物细胞，培养植物细胞的步骤和回收植物细胞的培养基的步骤。
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7.发明申请公开(公告)号：US20080124798A1
公开(公告)日：2008-05-29
申请号：US11810567
申请日：2007-06-06
Applicant: Tatsuji Seki , Kazuhito Fujiyama
Inventor： Tatsuji Seki , Kazuhito Fujiyama
IPC: C12N5/10
CPC classification number: C12N9/0065 , C12N9/1051 , C12N15/8242 , C12N15/8245 , C12N15/8257 , C12P21/005 , C12Y111/01007 , C12Y204/01038
Abstract: The present invention provides a method for manufacturing a glycoprotein having a human-type sugar chain comprising a step in which transformed plant cell is obtained by introducing to a plant cell the gene of glycosyltransferase and the gene of an exogenous glycoprotein, and a step in which the obtained transformed plant cell is cultivated.
Abstract translation: 本发明提供一种制备具有人型糖链的糖蛋白的方法，其包括通过向植物细胞中导入糖基转移酶的基因和外源性糖蛋白的基因而获得转化的植物细胞的步骤，其中， 培养获得的转化植物细胞。
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公开(公告)号：US20050143564A1
公开(公告)日：2005-06-30
申请号：US10870635
申请日：2004-06-17
Applicant: Tatsuji Seki , Kazuhito Fujiyama
Inventor： Tatsuji Seki , Kazuhito Fujiyama
IPC: A01H5/00 , C07K14/415 , C12N5/10 , C12N9/08 , C12N9/10 , C12N15/09 , C12N15/82 , C12P21/00 , C12P21/02
CPC classification number: C12N9/0065 , C12N9/1051 , C12N15/8242 , C12N15/8245 , C12N15/8257 , C12P21/005 , C12Y111/01007 , C12Y204/01038
Abstract: The present invention provides a method for manufacturing a glycoprotein having a human-type sugar chain comprising a step in which transformed plant cell is obtained by introducing to a plant cell the gene of glycosyltransfetase and the gene of an exogenous glycoprotein, and a step in which the obtained transformed plant cell is cultivated.
Abstract translation: 本发明提供一种制造具有人型糖链的糖蛋白的方法，其包括通过向植物细胞中导入糖基转移酶的基因和外源糖蛋白的基因而获得转化的植物细胞的步骤，其中， 培养获得的转化植物细胞。
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公开(公告)号：US08853370B2
公开(公告)日：2014-10-07
申请号：US13546293
申请日：2012-07-11
Applicant: Tatsuji Seki , Kazuhito Fujiyama
Inventor： Tatsuji Seki , Kazuhito Fujiyama
IPC: C07K16/00 , C07K14/00 , C07K14/435 , C07K14/475 , C12N9/08 , C12N15/82 , C12P21/00 , C12N9/10
CPC classification number: C12N9/0065 , C12N9/1051 , C12N15/8242 , C12N15/8245 , C12N15/8257 , C12P21/005 , C12Y111/01007 , C12Y204/01038
Abstract: The present invention provides a method for manufacturing a glycoprotein having a human-type sugar chain comprising a step in which transformed plant cell is obtained by introducing to a plant cell the gene of glycosyltransfetase and the gene of an exogenous glycoprotein, and a step in which the obtained transformed plant cell is cultivated.
Abstract translation: 本发明提供一种制造具有人型糖链的糖蛋白的方法，其包括通过向植物细胞中导入糖基转移酶的基因和外源糖蛋白的基因而获得转化的植物细胞的步骤，其中， 培养获得的转化植物细胞。
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公开(公告)号：US20110070649A1
公开(公告)日：2011-03-24
申请号：US12795316
申请日：2010-06-07
Applicant: Tatsuji Seki , Kazuhito Fujiyama
Inventor： Tatsuji Seki , Kazuhito Fujiyama
IPC: C12N5/10
CPC classification number: C12N9/0065 , C12N9/1051 , C12N15/8242 , C12N15/8245 , C12N15/8257 , C12P21/005 , C12Y111/01007 , C12Y204/01038
Abstract: The present invention provides a method for manufacturing a glycoprotein having a human-type sugar chain comprising a step in which transformed plant cell is obtained by introducing to a plant cell the gene of glycosyltransfetase and the gene of an exogenous glycoprotein, and a step in which the obtained transformed plant cell is cultivated.
Abstract translation: 本发明提供一种制造具有人型糖链的糖蛋白的方法，其包括通过向植物细胞中导入糖基转移酶的基因和外源糖蛋白的基因而获得转化的植物细胞的步骤，其中， 培养获得的转化植物细胞。
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