摘要:
The disclosure relates to a genetic inheritance cancer predisposition panel utilizing targeted capture-based next-generation sequencing—the panel incorporates genes underlying well-characterized cancer syndromes and those associated with increased cancer risk. The disclosure further relates to methods of utilizing the genetic inheritance cancer predisposition panel for determining a cancer risk assessment for individuals with hereditary cancers and/or cancer syndromes.
摘要:
The disclosure provides a method and a system for network handover. The method includes: during a process that equipment hands over from a current network to another network, a driver receiving a network-disconnected message, and judging whether the network-disconnected message is sent from a Connection Manager (CM); if the network-disconnected message is sent from the CM, the driver reporting, to an operating system, a first signalling which identifies that the current network is disconnected; and if the network-disconnected message is not sent from the CM, the driver reporting, to the operating system, a second signalling which identifies that the current network is connected. By the adoption of the method and the system, power consumption of the equipment can be reduced.
摘要:
This disclosure describes a wearable fall detection device configured to utilize several methods that facilitate monitoring a wearer of the device. The device comprises a first sensor configured to generate elevation data that represents an elevation of the device, and a second sensor configured to generate acceleration data that represents a magnitude of acceleration of the device. The device also includes a processor configured to determine, based on the elevation data, an elevation of a floor located underneath the wearer, and detect a fall affecting the wearer. Detecting a fall may be done by determining that the acceleration data satisfies a fall hypothesis condition, and determining, based on the elevation data, that the apparatus is vertically displaced from the floor by less than a threshold distance.
摘要:
Materials and Methods for identifying lignin regulatory region-regulatory protein associations are disclosed. Materials and methods for modulating lignin accumulation are also disclosed. In addition, methods and materials for modulating (e.g., increasing or decreasing) the level of a component (e.g., protein, oil, lignin, carbon, a carotenoid, or a triterpenoid) in plants are disclosed.
摘要:
The invention is directed to methods and kits that allow for classification of non-small cell lung carcinoma tumors and cell lines according to genomic profiles, and methods of diagnosing, predicting clinical outcomes, and stratifying patient populations for clinical testing and treatment using the same.
摘要:
There are provided methods and systems for precisely controlling the surfactant concentration and character of ferroelectric nanoparticles in a ferroelectric liquid crystal dispersion. In an aspect, the invention provides an efficient FTIR technique to characterize the status and measure the distribution of the surfactant in ferroelectric particle dispersion. This allows for establishing a reproducible fabrication process for ferroelectric nanoparticle liquid crystal dispersions. The methods also maintain the nanoparticles ferroelectricity, which is provided by the addition of surfactant during a comminution process. The invention therefore optimizes both the milling time (to achieve small particle size and narrow size distribution) and surfactant concentration (to maintain the ferroelectricity during milling).
摘要:
Provided herein are methods for the diagnosis, or management of liver diseases, e.g. hepatocellular carcinoma, using profiles of the miRNAs determined from cellular or acellular body fluids.
摘要:
Provided herein are methods for the diagnosis, staging, prognosis, or management of liver disease, e.g. chronic liver disease, and other diseases using profiles of the ubiquitin-proteasome system determined from acellular body fluids or cell-containing samples. Further provided are methods of predicting response to therapy in certain populations of patients with liver disease.
摘要:
Provided herein are methods for the diagnosis, or management of liver diseases, e.g., hepatocellular carcinoma, using profiles of the miRNAs determined from cellular or acellular body fluids.
摘要:
Disclosed are methods for identifying early-stage non-small-cell lung cancer (NSCLC) patients who will have an unfavorable prognosis for the recurrence of lung cancer after surgical resection. The methods are based in part on the discovery that chromosomal copy number gains at Chr19, 34.7 Mb-35.6 Mb can be used for prognostic classification. The methods preferably use fluorescence in situ hybridization with fluorescently labeled nucleic acid probes to hybridize to patient samples to quantify the chromosomal copy number of this genetic locus.