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公开(公告)号：US20130018247A1
公开(公告)日：2013-01-17
申请号：US13281399
申请日：2011-10-25
CPC分类号： A61N1/05 , A61B5/0422 , A61B5/6862 , A61N1/057
摘要： An intravascular electrode device for use in neuromodulation includes an anchor expandable from a radially compressed position to a radially expanded position. A lead extends from the anchor and has at least one conductor extending through it. A flex circuit is coupled to the anchor and comprises a flexible insulative substrate, a plurality of electrodes carried by the substrate, and a plurality of conductive traces carried by the substrate, each trace electrically coupled to an electrode and a conductor. Expansion of the anchor within a blood vessel biases the electrodes into contact with the surrounding blood vessel wall. An exemplary anchor includes a first portion having expansion forces sufficient to bias the electrodes against the vessel wall for mapping and chronic stimulation, and a second portion having greater radial expansion forces sufficient to chronically engage the vessel wall once an optimal electrode location has been selected.
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公开(公告)号：US20110125246A1
公开(公告)日：2011-05-26
申请号：US12987713
申请日：2011-01-10
申请人： Terrance Ransbury , Kevin Holbrook
发明人： Terrance Ransbury , Kevin Holbrook
IPC分类号： A61F2/84
CPC分类号： A61N1/056 , A61B17/064 , A61B17/068 , A61B2017/0649 , A61M39/0613 , A61N1/0573 , A61N2001/0578
摘要： Improved methods and apparatuses for positioning intravascular implantable device (IID) in a patient's vasculature utilize a device delivery system having an elongated flexible body. A handle can be operably connected to the proximal end and a grasper mechanism can be positioned at the distal end of the device delivery system. The grasper mechanism can be configured to releasably grasp the IID by closing a releasable honda around the IID and can be selectively controllable with the handle.
摘要翻译： 用于在患者的脉管系统中定位血管内可植入装置（IID）的改进的方法和装置利用具有细长的柔性体的装置递送系统。 手柄可以可操作地连接到近端，并且抓紧机构可以定位在装置输送系统的远端。 抓紧机构可以构造成通过闭合IID周围的可释放本体来可释放地抓住IID，并且可以用手柄选择性地控制。
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3.发明申请公开(公告)号：US20110054555A1
公开(公告)日：2011-03-03
申请号：US12908086
申请日：2010-10-20
CPC分类号： A61N1/057 , A61N1/37205 , A61N1/375
摘要： The present application describes a retention device for anchoring a medical device within the vasculature. The device may include expandable member coupled to an intravascular medical device and proportioned for receipt within a vessel. At least a portion of the expandable member is expandable to radially engage a vessel wall and to thereby retain the medical device within the vessel. The system is suitable for a variety of intravascular devices, including but not limited to ICD's, pacemakers, and intravascular drug delivery systems.
摘要翻译： 本申请描述了用于将医疗装置锚定在脉管系统内的保持装置。 该装置可以包括联接到血管内医疗装置并且成比例地用于在容器内接收的可扩张构件。 可膨胀构件的至少一部分可扩张以径向接合容器壁并由此将医疗装置保持在容器内。 该系统适用于各种血管内装置，包括但不限于ICD，起搏器和血管内药物递送系统。
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公开(公告)号：US20090048583A1
公开(公告)日：2009-02-19
申请号：US12251216
申请日：2008-10-14
IPC分类号： A61K9/22
CPC分类号： A61M25/04 , A61B5/0215 , A61B5/145 , A61B5/14532 , A61F2/82 , A61F2250/0068 , A61M5/14216 , A61M5/14232 , A61M5/14236 , A61M5/14276 , A61M5/172 , A61M2205/3523
摘要： Described herein is a system for intravascular drug delivery system, which includes a reservoir implantable a blood vessel, an intravascular pump fluidly coupled to the reservoir and an anchor expandable into contact with a wall of the blood vessel to retain the system within the vasculature. Delivery conduits may be extend from the reservoir and are positionable at select locations within the vasculature for target drug delivery to select organs or tissues.
摘要翻译： 本文描述了一种用于血管内药物递送系统，其包括可植入血管的血管，流体耦合到储器的血管内泵，以及可膨胀成与血管壁接触以将系统保持在脉管系统内的锚固体。 输送管道可以从储存器延伸并且可定位在脉管系统内的选定位置，用于靶向药物递送以选择器官或组织。
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公开(公告)号：US08886340B2
公开(公告)日：2014-11-11
申请号：US12908086
申请日：2010-10-20
IPC分类号： A61N1/02
CPC分类号： A61N1/057 , A61N1/37205 , A61N1/375
摘要： The present application describes a retention device for anchoring a medical device within the vasculature. The device may include expandable member coupled to an intravascular medical device and proportioned for receipt within a vessel. At least a portion of the expandable member is expandable to radially engage a vessel wall and to thereby retain the medical device within the vessel. The system is suitable for a variety of intravascular devices, including but not limited to ICD's, pacemakers, and intravascular drug delivery systems.
摘要翻译： 本申请描述了用于将医疗装置锚定在脉管系统内的保持装置。 该装置可以包括联接到血管内医疗装置并且成比例地用于在容器内接收的可扩张构件。 可膨胀构件的至少一部分可扩张以径向接合容器壁并由此将医疗装置保持在容器内。 该系统适用于各种血管内装置，包括但不限于ICD，起搏器和血管内药物递送系统。
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公开(公告)号：US08311633B2
公开(公告)日：2012-11-13
申请号：US11999519
申请日：2007-12-04
申请人： Terrance Ransbury , Kevin Holbrook
发明人： Terrance Ransbury , Kevin Holbrook
IPC分类号： A61N1/372
摘要： Anchoring methods, systems and devices anchor an intravascular implantable device within a vessel that is located superior to the heart, i.e. above the heart in a direction toward the head of a patient. A method of providing an intravascular device and instructions for implanting the intravascular device, includes providing an intravascular device having an elongate device body with a proximal end and a distal end that is adapted for chronic implantation within the vasculature of a patient and that includes a distal portion of the intravascular device proximate the distal end of the elongate device body, and providing instructions for chronically implanting the intravascular device substantially wholly within the vasculature of a patient in a target vessel superior to the heart of the patient.
摘要翻译： 锚定方法，系统和装置将血管内可植入装置固定在位于心脏上方的血管内，即在朝向患者头部方向的心脏上方。 一种提供血管内装置和用于植入血管内装置的说明书的方法，包括提供具有细长装置主体的血管内装置，所述细长装置本体具有适于在患者脉管系统内慢慢植入的近端和远端，并且包括远端 靠近细长装置主体的远端的血管内装置的部分，以及提供用于长期地将血管内装置基本上全部置于患者脉管系统内的指令，所述脉管系统优先于患者的心脏。
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7.发明申请公开(公告)号：US20110071585A1
公开(公告)日：2011-03-24
申请号：US12957969
申请日：2010-12-01
申请人： Terrance Ransbury , Kevin Holbrook
发明人： Terrance Ransbury , Kevin Holbrook
摘要： Methods, systems and devices are provided for anchoring an intravascular implantable device within a vessel that is located superior to the heart, i.e. above the heart in a direction toward the head of a patient. Also provided is a method of providing an intravascular device and instructions for implanting the intravascular device, comprising providing an intravascular device having an elongate device body with a proximal end and a distal end that is adapted for chronic implantation within the vasculature of a patient and that includes a distal portion of the intravascular device proximate the distal end of the elongate device body, and providing instructions for chronically implanting the intravascular device substantially wholly within the vasculature of a patient in a target vessel superior to the heart of the patient.
摘要翻译： 提供了方法，系统和装置，用于将血管内可植入装置固定在位于心脏上方的血管内，即在朝向患者头部的方向上方的心脏上方。 还提供了一种提供血管内装置和用于植入血管内装置的说明书的方法，其包括提供具有细长装置主体的血管内装置，所述细长装置主体具有近端和远端，所述近端和远端适于在患者脉管系统内慢慢植入，并且 包括靠近细长装置主体的远端的血管内装置的远端部分，以及提供用于将血管内装置基本上全部置于患者脉管系统内的指令，用于高于患者心脏的目标血管。
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公开(公告)号：US07840282B2
公开(公告)日：2010-11-23
申请号：US12506232
申请日：2009-07-20
IPC分类号： A61N1/02
CPC分类号： A61N1/057 , A61N1/37205 , A61N1/375
摘要： A retention device for anchoring a medical device within the vasculature is described. The device may include expandable member coupled to an intravascular medical device and proportioned for receipt within a vessel. At least a portion of the expandable member is expandable to radially engage a vessel wall and to thereby retain the medical device within the vessel. The system is suitable for a variety of intravascular devices, including but not limited to ICD's, pacemakers, and intravascular drug delivery systems.
摘要翻译： 描述了用于将医疗装置锚定在脉管系统内的保持装置。 该装置可以包括联接到血管内医疗装置并且成比例地用于在容器内接收的可扩张构件。 可膨胀构件的至少一部分可扩张以径向接合容器壁并由此将医疗装置保持在容器内。 该系统适用于各种血管内装置，包括但不限于ICD，起搏器和血管内药物递送系统。
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公开(公告)号：US20080167702A1
公开(公告)日：2008-07-10
申请号：US11999519
申请日：2007-12-04
申请人： Terrance Ransbury , Kevin Holbrook
发明人： Terrance Ransbury , Kevin Holbrook
摘要： Methods, systems and devices are provided for anchoring an intravascular implantable device within a vessel that is located superior to the heart, i.e. above the heart in a direction toward the head of a patient. Also provided is a method of providing an intravascular device and instructions for implanting the intravascular device, comprising providing an intravascular device having an elongate device body with a proximal end and a distal end that is adapted for chronic implantation within the vasculature of a patient and that includes a distal portion of the intravascular device proximate the distal end of the elongate device body, and providing instructions for chronically implanting the intravascular device substantially wholly within the vasculature of a patient in a target vessel superior to the heart of the patient.
摘要翻译： 提供了方法，系统和装置，用于将血管内可植入装置固定在位于心脏上方的血管内，即在朝向患者头部的方向上方的心脏上方。 还提供了一种提供血管内装置和用于植入血管内装置的说明书的方法，其包括提供具有细长装置主体的血管内装置，所述细长装置主体具有近端和远端，所述近端和远端适于在患者脉管系统内慢慢植入，并且 包括靠近细长装置主体的远端的血管内装置的远端部分，以及提供用于将血管内装置基本上全部置于患者脉管系统内的指令，用于高于患者心脏的目标血管。
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公开(公告)号：US20070043440A1
公开(公告)日：2007-02-22
申请号：US10571580
申请日：2004-09-17
申请人： Michael William , Jeffrey Smith , Richard Stack , Kevin Holbrook , Richard Glenn
发明人： Michael William , Jeffrey Smith , Richard Stack , Kevin Holbrook , Richard Glenn
IPC分类号： A61F2/44
CPC分类号： A61B17/8858 , A61B17/70 , A61B2017/00867
摘要： An apparatus according to the invention may comprise one or more expandable structural support pylons (140), means for deploying said one or more structural support pylons (138, 141), and one or more therapeutic substances. Structural support pylons (20) may comprise an elastomeric core (22), or may comprise one or more suitable metals, and may be deployed by shortening the length and increasing the height of the pylon. Alternatively, scaffold (200) may comprise a delivery configuration in which first unit (202) and second unit (204) he generally end to end, and a deployed configuration in which superior surfaces (216) and (218) exert an upward force and inferior surfaces (220) and (222) exert a downward force on superior and inferior vertebral surfaces respectively. A method according to the invention may comprise accessing an interior of a diseased or injured bone in a minimally invasive manner, creating a semi-circular path within said bone, deploying one or more structural support pylons within said interior, introducing structural reinforcement material, and if desired, repeating with one or more subsequent structural support pylons.
摘要翻译： 根据本发明的装置可以包括一个或多个可膨胀结构支撑塔（140），用于展开所述一个或多个结构支撑塔（138,141）的装置和一个或多个治疗物质。 结构支撑塔（20）可以包括弹性体芯（22），或者可以包括一种或多种合适的金属，并且可以通过缩短长度和增加塔的高度来展开。 或者，脚手架（200）可以包括其中大致端对端的第一单元（202）和第二单元（204）以及上表面（216）和（218）施加向上的力的展开构造的输送构型， 下表面（220）和（222）分别在上下椎体表面上施加向下的力。 根据本发明的方法可以包括以微创方式进入患病或受伤的骨骼的内部，在所述骨骼内产生半圆形路径，在所述内部内展开一个或多个结构支撑塔，引入结构增强材料，以及 如果需要，用一个或多个随后的结构支撑塔重复。
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