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公开(公告)号：US20100173835A1
公开(公告)日：2010-07-08
申请号：US12626188
申请日：2009-11-25
CPC分类号： C07K14/685 , A61K47/542 , A61K47/545
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的治疗方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US20130012432A1
公开(公告)日：2013-01-10
申请号：US13580042
申请日：2011-02-28
申请人： Kilian Waldemar Conde-Frieboes , Jane Spetzler , Ulrich Sensfuss , Birgitte Schjellerup Wulff , Henning Thoegersen , Jens Christian Norrild
发明人： Kilian Waldemar Conde-Frieboes , Jane Spetzler , Ulrich Sensfuss , Birgitte Schjellerup Wulff , Henning Thoegersen , Jens Christian Norrild
IPC分类号： A61K38/12 , A61P3/10 , A61P3/04 , A61P3/00 , A61P35/00 , A61P15/00 , A61P9/12 , A61P1/16 , A61P19/08 , A61P19/02 , A61P29/00 , A61P37/06 , C07K7/56 , A61P9/00
CPC分类号： C07K14/68
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的治疗方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US07541430B2
公开(公告)日：2009-06-02
申请号：US11268268
申请日：2005-11-07
申请人： Ulrich Sensfuss , Kilian Waldemar Conde Frieboes , Leif Christensen , Ingrid Vivika Petterson , Thomas Kruse Hansen , Michael Ankersen , Kjeld Madsen
发明人： Ulrich Sensfuss , Kilian Waldemar Conde Frieboes , Leif Christensen , Ingrid Vivika Petterson , Thomas Kruse Hansen , Michael Ankersen , Kjeld Madsen
IPC分类号： A61K38/10
摘要： Novel cyclic and linear peptides of the formula R1—X—X1—X2—X3—X4—X5—X6—X7—X8—X9—X10—X11—R2 are useful in the treatment of obesity are provided.
摘要翻译： 式R1-X-X1-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11-R2的新型环状和线性肽可用于治疗肥胖症。
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公开(公告)号：US20140018290A1
公开(公告)日：2014-01-16
申请号：US13979773
申请日：2012-01-24
IPC分类号： C07K14/575 , A61K38/22
CPC分类号： C07K14/5759 , A61K38/22 , A61K38/2264 , A61K47/542 , A61K47/545
摘要： The invention relates to Leptin derivatives, compositions and therapeutic use there-of.
摘要翻译： 本发明涉及瘦蛋白衍生物，组合物和治疗用途。
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公开(公告)号：US20110098213A1
公开(公告)日：2011-04-28
申请号：US11666794
申请日：2005-11-04
IPC分类号： A61K38/12 , C07K7/56 , C07K7/08 , A61K38/10 , A61P3/04 , A61P25/00 , A61P9/10 , A61P9/12 , A61P3/06 , A61P9/00 , A61P19/02 , A61P35/00 , A61P1/16
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的治疗方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US20090203581A1
公开(公告)日：2009-08-13
申请号：US11995351
申请日：2006-07-07
申请人： Ulrich Sensfuss , Leif Christensen , Jane Spetzler , Kilian Waldemar Conde Frieboes , Henning Thogersen
发明人： Ulrich Sensfuss , Leif Christensen , Jane Spetzler , Kilian Waldemar Conde Frieboes , Henning Thogersen
CPC分类号： C07K14/685 , A61K47/542 , A61K47/545
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的治疗方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US20080200366A1
公开(公告)日：2008-08-21
申请号：US11911428
申请日：2006-04-07
CPC分类号： C07K14/68
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型的新型肽化合物，治疗中化合物的用途，包括向有需要的患者施用化合物的治疗方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US20120021973A1
公开(公告)日：2012-01-26
申请号：US13130839
申请日：2009-11-24
IPC分类号： A61K38/12 , A61P3/04 , A61P3/10 , A61P25/00 , A61P15/00 , A61P3/06 , A61P9/00 , A61P1/16 , A61P19/02 , A61P35/00 , C07K7/56 , A61P9/10
CPC分类号： C07K14/685 , A61K47/542 , A61K47/545
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
摘要翻译： 本发明涉及有效调节一种或多种黑皮质素受体类型，化合物在治疗中的用途的新型肽化合物，包括向有需要的患者施用化合物的方法，以及使用 药物制造中的化合物。 本发明的化合物在治疗肥胖以及与肥胖相关的各种疾病或病症方面特别有意义。
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公开(公告)号：US20100029903A1
公开(公告)日：2010-02-04
申请号：US12097194
申请日：2006-12-13
IPC分类号： C07K14/605 , C07K14/00 , C07F9/38 , C07F9/09
CPC分类号： C07K14/605 , A61K47/548 , C07F9/091 , C07F9/4006 , C07F9/6561
摘要： The invention provides novel compounds comprising a protracting tag linked to therapeutically active compounds.
摘要翻译： 本发明提供了包含与治疗活性化合物连接的延伸标签的新型化合物。
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公开(公告)号：US20100016237A1
公开(公告)日：2010-01-21
申请号：US12521906
申请日：2008-01-17
CPC分类号： C07K14/68
摘要： The present invention relates to novel peptide compounds which are effective in modulating one or more melanocortin receptor types, to the use of the compounds in therapy, to methods of treatment comprising administration of the compounds to patients in need thereof, and to the use of the compounds in the manufacture of medicaments. The compounds of the invention are of particular interest in relation to the treatment of obesity as well as a variety of diseases or conditions associated with obesity.
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