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1.Method of inhibiting amyloid protein aggregation and imaging amyloid deposits 失效
标题翻译: 抑制淀粉样蛋白聚集和成像淀粉样沉积物的方法公开(公告)号:US06972287B1
公开(公告)日:2005-12-06
申请号:US10009611
申请日:2000-05-31
申请人: Corinne Elizabeth Augelli-Szafran , Mark Robert Barvian , Christopher Franklin Bigge , Shelly Ann Glase , Shunichiro Hachiya , John Steven Kiely , Takenori Kimura , Yingjie Lai , Annette Theresa Sakkab , Mark James Suto , Larry Craswell Walker , Tomoyuki Yasunaga , Nian Zhuang
发明人: Corinne Elizabeth Augelli-Szafran , Mark Robert Barvian , Christopher Franklin Bigge , Shelly Ann Glase , Shunichiro Hachiya , John Steven Kiely , Takenori Kimura , Yingjie Lai , Annette Theresa Sakkab , Mark James Suto , Larry Craswell Walker , Tomoyuki Yasunaga , Nian Zhuang
IPC分类号: A61K31/196 , A61K31/402 , A61K31/4164 , C07C229/58 , C07C229/62 , C07C229/64 , C07C233/43 , C07C311/51 , C07D209/44 , C07D213/82 , C07D217/02 , C07D233/88 , C07D257/04 , C07D295/135 , C07D317/58 , C07D413/06 , C07D401/10 , A61K31/41 , A61P25/28 , C07D403/10 , C07D413/10
CPC分类号: C07D213/82 , A61K31/196 , A61K31/402 , A61K31/4164 , C07C229/58 , C07C229/62 , C07C229/64 , C07C233/43 , C07C311/51 , C07D209/44 , C07D217/02 , C07D233/88 , C07D257/04 , C07D295/135 , C07D317/58 , C07D413/06
摘要: The present invention provides a method of treating Alzheimer's disease using a compound of Formula (I). Also provided is a method of inhibiting the aggregation of amyloid proteins using a compound of the Formula (I) and a method of imaging amyloid deposits, as well as new compounds of Formula (I).
摘要翻译: 本发明提供使用式(I)的化合物治疗阿尔茨海默病的方法。 还提供了使用式(I)化合物和淀粉样沉积物成像方法以及式(I)的新化合物抑制淀粉样蛋白聚集的方法。