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1.Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes 失效
标题翻译: 用作黑色素浓缩激素拮抗剂治疗肥胖和糖尿病的多环化合物公开(公告)号:US07229987B2
公开(公告)日:2007-06-12
申请号:US10512986
申请日:2003-05-06
申请人: Jochen Ammenn , James Ronald Gillig , Lawrence Joseph Heinz , Philip Arthur Hipskind , Michael Dean Kinnick , Yen-Shi Lai , John Michael Morin, Jr. , James Arthur Nixon , Carsten Ott , Kenneth Allen Savin , Theo Schotten , Lawrence John Slieker , Nancy June Snyder , Michael Alan Robertson
发明人: Jochen Ammenn , James Ronald Gillig , Lawrence Joseph Heinz , Philip Arthur Hipskind , Michael Dean Kinnick , Yen-Shi Lai , John Michael Morin, Jr. , James Arthur Nixon , Carsten Ott , Kenneth Allen Savin , Theo Schotten , Lawrence John Slieker , Nancy June Snyder , Michael Alan Robertson
IPC分类号: A61K31/5355 , A61K31/454 , C07D401/12 , C07D403/12 , C07D263/32
CPC分类号: C07D249/08 , C07D261/08 , C07D263/32 , C07D271/06 , C07D271/10 , C07D271/107 , C07D277/26 , C07D333/18 , C07D413/04 , C07D413/06 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/12
摘要: The present invention relates to a melanin concentrating hormone antagonist compound of formula I: (I); or a pharmaceutically acceptable salt, solvate, enantiomer or prodrug thereof useful in the treatment, prevention or amelioration of symptoms associated with obesity and related diseases.
摘要翻译: 本发明涉及式I的黑色素浓缩激素拮抗剂化合物:(I); 或其药学上可接受的盐,溶剂化物,对映异构体或前药,用于治疗,预防或改善与肥胖症和相关疾病相关的症状。