Chemical synthesis method of phillyrin

    公开(公告)号:US10400004B2

    公开(公告)日:2019-09-03

    申请号:US15502085

    申请日:2014-12-23

    申请人: Li Fu

    发明人: Li Fu

    IPC分类号: C07H15/26 C07H1/00

    摘要: The present invention relates to a chemical synthesis method for phillyrin. The method of the present invention comprises: first dissolving a glycosyl receptor phillygenin and a glycosyl donor in an organic solvent for glycosylation to obtain tetraacyl phillyrin; then dissolving the tetraacyl phillyrin in a second organic solvent, and adding sodium methoxide for deacylation, adding an acidic pH regulator to regulate the pH value of the reaction mixture to neutral; and finally carrying out purification treatment to obtain phillyrin. The advantages and practical values of the chemical synthesis method for phillyrin of the present invention lie in: the raw material is easy to get, the catalysts used for glycosylation are cheap and easy to get, the production cost is greatly reduced, and it can be used for industrial production.

    Aqueous solution of 20(R)-ginsenoside RG3 pharmaceutical composition and process thereof
    2.
    发明授权
    Aqueous solution of 20(R)-ginsenoside RG3 pharmaceutical composition and process thereof 有权
    20(R) - 人参皂苷RG3药物组合物的水溶液及其制备方法

    公开(公告)号:US09333215B2

    公开(公告)日:2016-05-10

    申请号:US13941106

    申请日:2013-07-12

    申请人: Li Fu

    发明人: Li Fu Qi Lu

    摘要: A preparation of a kind of 20(R)-ginsenoside Rg3 medicinal composition aqueous solution containing ginsenoside Rg3 0.5˜10 mg/ml: add 0.1-5% of ginsenoside solution to 0.1˜30% of adjuvant A, B{circle around (1)}{circle around (2)}{circle around (5)} at the temperature of 40˜100° C., the ratio of these two is 1:1˜300, add water after the solvent is recycled under reduced pressure; another kind of 20(R)-ginsenoside Rg3 medicinal composition aqueous solution contains 0.1˜2 mg/ml of 20 (R) of the ginsenoside Rg3, the preparation: add 0.1˜5% of ginsenoside solution to 20˜65% of adjuvant B{circle around (3)}{circle around (4)} at the temperature of 60˜100° C., main material to adjuvant B=1:100˜400, add water after the solvent is recycled under reduced pressure. The above 20 (R) ginsenoside Rg3 composition aqueous solution and the powder after lyophilization can be used to prepare injectable, oral administration and external use, and the bioactivity of these preparations is high, and with the actions of anti cancer, efficacy potentiation and toxicity attenuation effects of the combined chemical or radiation therapy of tumor, enhancement of human immune functions, improvement of human memory, anti fatigue, and detumescence, pain relieving.

    摘要翻译: 含有人参皂甙Rg3的20(R) - 人参皂苷Rg3药物组合物水溶液0.5〜10mg / ml的制剂:将0.1〜30%的人参皂甙溶液加入0.1〜30%的佐剂A,B )} {圆周(2)} {圆周(5)}在40〜100℃的温度下,这两者的比例为1:1〜300,在减压下回收溶剂后加水; 另外一种20(R) - 人参皂甙Rg3药用组合物水溶液含有0.1〜2mg / ml的人参皂甙Rg3,其制备方法:将20〜65%的人参皂甙溶液加入0.1〜5% {圆周围(3)} {圆周围(4)},温度为60〜100℃,辅料B = 1:100〜400的主要原料,在减压下回收溶剂后加水。 上述20(R)人参皂苷Rg3组合物水溶液和冻干后的粉末可用于制备注射,口服和外用,并且这些制剂的生物活性高,并具有抗癌作用,功效增强和毒性 肿瘤组合化学或放射治疗的衰减效应,人体免疫功能的增强,人体记忆的改善,抗疲劳和消肿,疼痛缓解。

    Updating firmware in a display device using a serial bus
    3.
    发明授权
    Updating firmware in a display device using a serial bus 有权
    使用串行总线更新显示设备中的固件

    公开(公告)号:US08890877B2

    公开(公告)日:2014-11-18

    申请号:US12372402

    申请日:2009-02-17

    CPC分类号: G06F8/65

    摘要: Updating firmware of a display device. The display device may include a display screen and a video interface for receiving video signals from a host system and providing the video signals for display on the display screen. The display device may include a memory that stores program instructions for controlling operation of the display device. The display device may include a serial bus interface (e.g., a USB interface), which may receive signals from a host computer for updating the program instructions in the memory. A serial bus to first protocol bridge may receive the serial bus signals from the serial bus interface and convert the serial bus signals to signals of the first protocol. A display controller may update the program instructions in the memory of the display in response to the signals of the first protocol.

    摘要翻译: 更新显示设备的固件。 显示装置可以包括用于从主机系统接收视频信号的显示屏幕和视频接口,并提供用于在显示屏幕上显示的视频信号。 显示装置可以包括存储用于控制显示装置的操作的程序指令的存储器。 显示设备可以包括串行总线接口(例如,USB接口),其可以从主机接收信号以更新存储器中的程序指令。 到第一协议桥的串行总线可以从串行总线接口接收串行总线信号,并将串行总线信号转换成第一协议的信号。 响应于第一协议的信号,显示控制器可更新显示器的存储器中的程序指令。

    Water solution of 20(R)-ginsenoside Rg3 pharmaceutical composition and process thereof
    4.
    发明授权
    Water solution of 20(R)-ginsenoside Rg3 pharmaceutical composition and process thereof 有权
    20(R) - 人参皂苷Rg3药物组合物的水溶液及其制备方法

    公开(公告)号:US08487090B2

    公开(公告)日:2013-07-16

    申请号:US12301996

    申请日:2007-05-18

    申请人: Li Fu Qi Lu

    发明人: Li Fu Qi Lu

    摘要: A preparation of a kind of 20(R)-ginsenoside Rg3 medicinal composition aqueous solution containing ginsenoside Rg3 0.5˜10 mg/ml: add 0.1-5% of ginsenoside solution to 0.1˜30% of adjuvant A, B{circle around (1)}{circle around (2)}{circle around (5)} at the temperature of 40˜100° C., the ratio of these two is 1:1˜300, add water after the solvent is recycled under reduced pressure; another kind of 20(R)-ginsenoside Rg3 medicinal composition aqueous solution contains 0.1˜2 mg/ml of 20(R) of the ginsenoside Rg3, the preparation: add 0.1˜5% of ginsenoside solution to 20˜65% of adjuvant B{circle around (3)}{circle around (4)} at the temperature of 60˜100° C., main material to adjuvant B=1:100˜400, add water after the solvent is recycled under reduced pressure. The above 20(R) ginsenoside Rg3 composition aqueous solution and the powder after lyophilizaton can be used to prepare injectable, oral administration and external use, and the bioactivity of these preparations is high, and with the actions of anti cancer, efficacy potentiation and toxicity attenuation effects of the combined chemical or radiation therapy of tumor, enhancement of human immune functions, improvement of human memory, anti fatigue, and detumescence, pain relieving.

    摘要翻译: 制备一种含有人参皂甙Rg3的20(R) - 人参皂甙Rg3药物组合物水溶液0.5〜10mg / ml:将0.1〜30%人参皂甙溶液加入0.1〜30%的佐剂A,B )} {圆周(2)}(圆周围(5)}在40〜100℃的温度下,这两者的比例为1:1〜300,溶剂在减压下循环后加水; 另一种20(R) - 人参皂甙Rg3药用组合物水溶液含有0.1〜2mg / ml的20(R)人参皂甙Rg3,制备方法:将20%〜65%的人参皂甙溶液加0.1〜5% {圆周(3)} {圆周(4)}在60〜100℃的温度下,辅料B = 1:100〜400的主要原料,在减压下回收溶剂后加水。 上述20(R)人参皂苷Rg3组合物水溶液和冻干后的粉末可用于制备注射,口服和外用,并且这些制剂的生物活性高,并具有抗癌作用,功效增强和毒性 肿瘤组合化学或放射治疗的衰减效应,人体免疫功能的增强,人体记忆的改善,抗疲劳和消肿,疼痛缓解。

    HEAT DISSIPATING DEVICE SUPPORTING APPARATUS
    5.
    发明申请
    HEAT DISSIPATING DEVICE SUPPORTING APPARATUS 审中-公开
    加热设备支持设备

    公开(公告)号:US20130075567A1

    公开(公告)日:2013-03-28

    申请号:US13483293

    申请日:2012-05-30

    申请人: GAO-HUI FU LI-FU XU

    发明人: GAO-HUI FU LI-FU XU

    IPC分类号: H05K7/20

    摘要: A heat dissipating device supporting apparatus includes a base, and a securing element mounted to the mounting portion. The base includes a main body configured to support a heat dissipating device and a mounting portion extending from the main body. The securing element includes a fastener, an elastic member, and a mounting member. The mounting member includes a cavity portion, a supporting portion extending from the cavity portion, and a protrusion extending from an inner side the cavity portion. The supporting portion defines a through hole. The fastener includes a head portion and a shaft portion extending from the head portion. A cross-section of the head portion is greater than that of the shaft portion. The shaft portion is located in the through hole. The elastic member resists resiliently between the head portion and the supporting portion. The head portion resists between the elastic member and the protrusion.

    摘要翻译: 散热装置支撑装置包括基座和安装在安装部上的固定元件。 底座包括构造成支撑散热装置的主体和从主体延伸的安装部。 固定元件包括紧固件,弹性构件和安装构件。 安装构件包括空腔部分,从空腔部分延伸的支撑部分和从空腔部分的内侧延伸的突出部。 支撑部分限定通孔。 紧固件包括头部和从头部延伸的轴部。 头部的横截面大于轴部的横截面。 轴部位于通孔中。 弹性构件在头部和支撑部之间弹性地抵抗。 头部抵抗弹性构件和突起之间的抵抗。

    ELECTRONIC DEVICE ENCLOSURE
    6.
    发明申请
    ELECTRONIC DEVICE ENCLOSURE 失效
    电子设备外壳

    公开(公告)号:US20130063005A1

    公开(公告)日:2013-03-14

    申请号:US13482444

    申请日:2012-05-29

    IPC分类号: H05K5/02

    CPC分类号: G06F1/181

    摘要: An electronic device enclosure includes a rear panel and a blocking board. The rear panel comprises a front surface and a back surface opposite to the front surface. A through opening is defined in the rear panel. The blocking board comprises a main body, a first flange and a second flange opposite to the first flange. A first stopping piece is extends from the first flange. A second stopping piece is extended from the second flange. A latch portion is located on the first flange. A first protrusion is located on the second flange. The latch portion and the second protrusion extend through the through opening by being elastically deformed, the latch portion and the second protrusion abut on the front surface, and the first stopping piece and the second stopping piece abut on the back surface.

    摘要翻译: 电子设备外壳包括后面板和阻挡板。 后面板包括前表面和与前表面相对的后表面。 在后面板中定义了一个通孔。 阻挡板包括主体,第一凸缘和与第一凸缘相对的第二凸缘。 第一止动件从第一凸缘延伸。 第二止动件从第二凸缘延伸。 闩锁部分位于第一凸缘上。 第一凸起位于第二凸缘上。 闩锁部分和第二突起通过弹性变形延伸穿过通孔,闩锁部分和第二突起抵靠在前表面上,并且第一止动件和第二止动件抵靠在后表面上。

    ELECTRONIC DEVICE ENCLOSURE WITH BRACKET FOR DATA STORAGE DEVICE
    7.
    发明申请
    ELECTRONIC DEVICE ENCLOSURE WITH BRACKET FOR DATA STORAGE DEVICE 失效
    用于数据存储设备的带有支架的电子设备外壳

    公开(公告)号:US20130057127A1

    公开(公告)日:2013-03-07

    申请号:US13471615

    申请日:2012-05-15

    IPC分类号: H05K5/02

    CPC分类号: G06F1/187

    摘要: An enclosure includes a chassis and a bracket. The chassis includes a bottom panel, a rear panel and a side panel. The rear panel defines a latch hole. Two clamping pieces are located on the side panel. The bracket is engaged between the clamping pieces and includes a first sidewall and a second sidewall. A second hook and a resilient piece are located on the first sidewall. A first hook is located on the second sidewall. The first hook and the second hook are separately engaged with the two clamping pieces for preventing the bracket from moving along a first direction near to the bottom panel. The resilient piece is engaged in the latch hole to preventing the bracket from moving a second direction opposite to the first direction, and the resilient piece is elastically deformable to disengage from the lath hole.

    摘要翻译: 外壳包括底盘和支架。 底盘包括底板,后面板和侧板。 后面板限定了一个闩锁孔。 两个夹紧件位于侧面板上。 支架接合在夹紧件之间并且包括第一侧壁和第二侧壁。 第二钩和弹性片位于第一侧壁上。 第一钩位于第二侧壁上。 第一钩和第二钩分别与两个夹紧件接合,以防止支架沿着靠近底板的第一方向移动。 所述弹性件与所述闩锁孔接合以防止所述托架移动与所述第一方向相反的第二方向,并且所述弹性件可弹性变形以与所述板条孔脱离。

    ELECTRONIC DEVICE CONNECTOR
    8.
    发明申请
    ELECTRONIC DEVICE CONNECTOR 失效
    电子设备连接器

    公开(公告)号:US20130052852A1

    公开(公告)日:2013-02-28

    申请号:US13467121

    申请日:2012-05-09

    IPC分类号: H01R13/62

    CPC分类号: H01R13/6272

    摘要: A connector includes a body and a socket extending from the body. A blocking wall is located on the body. The socket includes a top wall, a resilient piece located on the top wall. The blocking wall is surrounded the resilient piece for preventing the resilient piece from destroying.

    摘要翻译: 连接器包括主体和从主体延伸的插座。 阻塞墙位于身体上。 插座包括顶壁,位于顶壁上的弹性片。 阻挡壁被弹性件包围,以防止弹性片破坏。

    Connector assembly
    9.
    发明授权
    Connector assembly 失效
    连接器组件

    公开(公告)号:US08357004B2

    公开(公告)日:2013-01-22

    申请号:US13241235

    申请日:2011-09-23

    IPC分类号: H01R13/62

    CPC分类号: H01R13/6272 H01R13/64

    摘要: A connector assembly includes a first connector with a positioning portion and a second connector with a latch. A blocking portion is located on a second side of the first connector. The latch defines an oblique latching plane, the positioning portion defines an oblique sliding plane, and the blocking portion defines an oblique blocking plane. If the latch is aligned with the positioning portion and is slid towards the first connector, the oblique direction of the second latching plane is substantially the same as the oblique positioning plane. If the latch is aligned with the blocking portion and is slid towards the first connector, an acute angle is defined between the oblique direction of the second latching plane and the oblique direction of the blocking plane.

    摘要翻译: 连接器组件包括具有定位部分的第一连接器和具有闩锁的第二连接器。 阻挡部分位于第一连接器的第二侧上。 闩锁限定倾斜的锁定平面,定位部分限定倾斜的滑动平面,并且阻挡部分限定倾斜的阻挡平面。 如果闩锁与定位部对准并且朝向第一连接器滑动,则第二闩锁平面的倾斜方向与倾斜定位平面基本相同。 如果闩锁与阻挡部分对准并且朝向第一连接器滑动,则在第二闩锁平面的倾斜方向和阻挡平面的倾斜方向之间限定锐角。

    System for Detecting a Liquid Sample
    10.
    发明申请
    System for Detecting a Liquid Sample 有权
    检测液体样品的系统

    公开(公告)号:US20120266662A1

    公开(公告)日:2012-10-25

    申请号:US13091435

    申请日:2011-04-21

    IPC分类号: G01N1/10

    摘要: A system is provided for detecting a liquid sample, and includes: a flow cell assembly formed with a sample receiving space therein, and inlet and outlet channels extending to the sample receiving space for guiding the liquid sample into and away from the sample receiving space; a sensor device including a sample detecting unit that is disposed in the sample receiving space, and that is operable to detect the liquid sample and to generate a detection signal accordingly, and a signal conducting unit that is connected electrically to the sensor device for conducting the detection signal therefrom; and a liquid introducing unit and a liquid discharging unit coupled to the inlet and outlet channels and cooperating therewith to form an introducing path and a discharging path for introducing the liquid sample into and for discharging the liquid sample from the sample receiving space, respectively.

    摘要翻译: 提供了一种用于检测液体样品的系统,包括:形成有样品容纳空间的流通池组件,以及延伸到样品容纳空间的入口和出口通道,用于将液体样品引入和离开样品接收空间; 传感器装置,包括:样本检测单元,其设置在样本容纳空间中,并且可操作地检测液体样本并相应地产生检测信号;以及信号导通单元,其与传感器装置电连接,用于导电 检测信号; 以及液体引入单元和液体排出单元,其联接到入口和出口通道并与之配合以形成引入路径和用于将液体样品分别从样品接收空间引入和排出液体样品的排出路径。