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公开(公告)号:US6027935A
公开(公告)日:2000-02-22
申请号:US660347
申请日:1996-06-05
申请人: Anthony F. Purchio , Liguo New , Kang Liu , Vafa Kamali , Brian Naughton
发明人: Anthony F. Purchio , Liguo New , Kang Liu , Vafa Kamali , Brian Naughton
IPC分类号: C12N15/09 , A01K67/027 , A61K38/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/16 , C07K14/475 , C07K14/81 , C12N5/10 , C12P21/08 , C12Q1/68 , C12N5/00 , C12N15/00 , C12N15/63
CPC分类号: C07K14/475 , C07K14/8121 , A61K38/00
摘要: The novel gene, Rasp-1, which is up-regulated in regenerating liver, is disclosed. The novel RASP-1 protein, which is encoded by the Rasp-1 gene, is also disclosed. In addition, antibodies against the Rasp-1 gene products are also disclosed. Furthermore, the use of Rasp-1 nucleic acid sequences, Rasp-1 gene products, and antibodies against Rasp-1 gene products in the treatment and diagnosis of liver disorders is also disclosed.
摘要翻译: 公开了在再生肝中上调的新基因Rasp-1。 还公开了由Rasp-1基因编码的新型RASP-1蛋白。 此外,还公开了针对Rasp-1基因产物的抗体。 此外,还公开了Rasp-1核酸序列,Rasp-1基因产物和针对Rasp-1基因产物的抗体在肝脏疾病的治疗和诊断中的用途。