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1.发明授权Oxylipins from stearidonic acid and γ-linolenic acid and methods of making and using the same 失效来自十八碳四烯酸和γ-亚麻酸的青霉素及其制备和使用方法公开(公告)号：US07893106B2
公开(公告)日：2011-02-22
申请号：US11669730
申请日：2007-01-31
Applicant: Linda Mary Arterburn , William Barclay , Bindi Dangi , James Flatt , Jung Lee , Dutt Vinjamoori
Inventor： Linda Mary Arterburn , William Barclay , Bindi Dangi , James Flatt , Jung Lee , Dutt Vinjamoori
CPC classification number: C12N15/8247 , C07C59/42 , C07D303/38 , C12P7/6427 , C12P7/6472
Abstract: Disclosed are novel oxylipins that are derived from γ-linolenic acid (GLA; 18:3n-6) and stearidonic acid (STA or SDA; 18:4n-3), and methods of making and using such oxylipins. Also disclosed is the use of such oxylipins in therapeutic and nutritional or cosmetic applications, and particularly as anti-inflammatory or anti-neurodegenerative compounds. Also disclosed are The invention novel ways of producing long chain polyunsaturated acid (LCPUFA)-rich oils and compositions that contain enhanced and effective amounts of SDA- and/or GLA-derived oxylipins.
Abstract translation: 公开了衍生自γ-亚麻酸（GLA; 18：3n-6）和十八碳四烯酸（STA或SDA; 18：4n-3）的新型oxylipin，以及制备和使用这种oxylipin的方法。 还公开了在治疗和营养或化妆品应用中使用这种oxylipin，特别是作为抗炎或抗神经变性化合物。 还公开了本发明新颖的生产长链多不饱和酸（LCPUFA）的油和组合物的新方法，其含有增强和有效量的SDA和/或GLA衍生的草甘膦。
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2.发明申请Long Chain Polyunsaturated Fatty Acids and Methods of Making and Using the Same 审中-公开长链多不饱和脂肪酸及其制备和使用方法
公开(公告)号：US20090318394A1
公开(公告)日：2009-12-24
申请号：US12357388
申请日：2009-01-21
Applicant: Julie Nauroth , Linda Mary Arterburn , Mary Van Elswyk
Inventor： Julie Nauroth , Linda Mary Arterburn , Mary Van Elswyk
CPC classification number: A61K31/616 , A23D9/013 , A23K20/158 , A23L33/12 , A61K8/365 , A61K8/37 , A61K31/22 , A61K31/60 , A61Q19/00 , A61K2300/00
Abstract: Disclosed are compositions containing DHA and DPAn-6 and methods of administering and using the same to treat or prevent at least one symptom of inflammation or neurodegeneration or disease states associated with inflammation or neurodegeneration. Also discloses are compositions containing specific dosages and/or ratios of long chain polyunsaturated fatty acids that are particularly effective in reducing or preventing symptoms of inflammation or neurodegeneration.
Abstract translation: 公开了含有DHA和DPAn-6的组合物，以及施用和使用它们以治疗或预防与炎症或神经变性相关的炎症或神经变性或疾病状态的至少一种症状的方法。 还公开了包含特定剂量和/或比例的长链多不饱和脂肪酸的组合物，其特别有效地减少或预防炎症或神经变性的症状。
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3.发明申请OXYLIPINS FROM STEARIDONIC ACID AND GAMMA-LINOLENIC ACID AND METHODS OF MAKING AND USING SAME 审中-公开来自硬脂酸和γ-亚麻酸的氧化剂及其制备和使用方法
公开(公告)号：US20110112191A1
公开(公告)日：2011-05-12
申请号：US13009218
申请日：2011-01-19
Applicant: Linda Mary Arterburn , William Barclay , Bindi Dangi , James Flatt , Jung Lee , Dutt Vinjamoori
Inventor： Linda Mary Arterburn , William Barclay , Bindi Dangi , James Flatt , Jung Lee , Dutt Vinjamoori
IPC: A61K31/202 , C07C59/42 , A61P29/00 , A61P25/00
CPC classification number: C12N15/8247 , C07C59/42 , C07D303/38 , C12P7/6427 , C12P7/6472
Abstract: Disclosed are novel oxylipins that are derived from γ-linolenic acid (GLA; 18:3n-6) and stearidonic acid (STA or SDA; 18:4n-3), and methods of making and using such oxylipins. Also disclosed is the use of such oxylipins in therapeutic and nutritional or cosmetic applications, and particularly as anti-inflammatory or anti-neurodegenerative compounds. Also disclosed are The invention novel ways of producing long chain polyunsaturated acid (LCPUFA)-rich oils and compositions that contain enhanced and effective amounts of SDA- and/or GLA-derived oxylipins.
Abstract translation: 公开了衍生自γ-亚麻酸（GLA; 18：3n-6）和十八碳四烯酸（STA或SDA; 18：4n-3）的新型oxylipin，以及制备和使用这种oxylipin的方法。 还公开了在治疗和营养或化妆品应用中使用这种oxylipin，特别是作为抗炎或抗神经变性化合物。 还公开了本发明新颖的生产长链多不饱和酸（LCPUFA）的油和组合物的新方法，其含有增强和有效量的SDA和/或GLA衍生的草甘膦。
