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公开(公告)号:US20050215626A1
公开(公告)日:2005-09-29
申请号:US10947930
申请日:2004-09-23
申请人: Lisa Havran , John Butera , Hassan Elokdah , Douglas Jenkins , Eric Gundersen
发明人: Lisa Havran , John Butera , Hassan Elokdah , Douglas Jenkins , Eric Gundersen
IPC分类号: A61P7/02 , C07D307/81 , A61K31/343 , C07D307/78
CPC分类号: C07D307/81
摘要: The present invention relates to substituted benzofuran oximes and methods of using them.
摘要翻译: 本发明涉及取代的苯并呋喃肟及其使用方法。
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公开(公告)号:US20050250798A1
公开(公告)日:2005-11-10
申请号:US11061144
申请日:2005-02-18
申请人: Paul Dollings , Arlene Dietrich , Lisa Havran , Chae-Koo Chong , Donna Huryn , Albert Robichaud , Boyd Harrison , Wayne Childers , Alexander Greenfield , James Bicksler
发明人: Paul Dollings , Arlene Dietrich , Lisa Havran , Chae-Koo Chong , Donna Huryn , Albert Robichaud , Boyd Harrison , Wayne Childers , Alexander Greenfield , James Bicksler
IPC分类号: A61K31/519 , C07D487/04 , C07D487/10
CPC分类号: C07D487/04 , C07D487/10
摘要: Novel pyrimidoindolone compounds are disclosed. Methods of using the pyrimidoindolone compounds and compositions containing the compounds in the treatment and/or prevention of disease and other conditions related to inflammation, neurodegeneration, osteoarthritis and apoptosis are also disclosed.
摘要翻译: 公开了新的嘧啶吲哚酮化合物。 还公开了使用嘧啶吲哚酮酮化合物和含有该化合物的组合物在治疗和/或预防与炎症,神经变性,骨关节炎和细胞凋亡相关的疾病和其它病状的方法。
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公开(公告)号:US20050119326A1
公开(公告)日:2005-06-02
申请号:US10947846
申请日:2004-09-23
申请人: Lisa Havran , John Butera , Hassan Elokdah , Douglas Jenkins , Eric Gundersen
发明人: Lisa Havran , John Butera , Hassan Elokdah , Douglas Jenkins , Eric Gundersen
IPC分类号: A61K31/15 , A61K31/405 , A61P7/02 , C07C251/60 , C07D209/14 , C07D43/02
CPC分类号: C07D209/14
摘要: The present invention relates to substituted indole oximes and methods of using them.
摘要翻译: 本发明涉及取代的吲哚肟及其使用方法。
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公开(公告)号:US20070270587A1
公开(公告)日:2007-11-22
申请号:US11772549
申请日:2007-07-02
申请人: Paul Dollings , Arlene Dietrich , Lisa Havran , Chae-Koo Chong , Donna Huryn , Albert Robichaud , Boyd Harrison , Wayne Childers , Alexander Greenfield , James Bicksler , Vasilios Marathias
发明人: Paul Dollings , Arlene Dietrich , Lisa Havran , Chae-Koo Chong , Donna Huryn , Albert Robichaud , Boyd Harrison , Wayne Childers , Alexander Greenfield , James Bicksler , Vasilios Marathias
IPC分类号: C07D239/70
CPC分类号: C07D487/04 , C07D487/10
摘要: Novel pyrimidoindolone compounds are disclosed. Methods of using the pyrimidoindolone compounds and compositions containing the compounds in the treatment and/or prevention of disease and other conditions related to inflammation, neurodegeneration, osteoarthritis and apoptosis are also disclosed.
摘要翻译: 公开了新的嘧啶吲哚酮化合物。 还公开了使用嘧啶吲哚酮酮化合物和含有该化合物的组合物在治疗和/或预防与炎症,神经变性,骨关节炎和细胞凋亡相关的疾病和其它病状的方法。
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5.Piperazine-piperidine antagonists and agonists of the 5-HT1A receptor 失效
标题翻译: 哌嗪 - 哌啶拮抗剂和5-HT1A受体的激动剂公开(公告)号:US20070027160A1
公开(公告)日:2007-02-01
申请号:US11450942
申请日:2006-06-09
申请人: Magda Asselin , George Grosu , Annmarie Sabb , Wayne Childers , Lisa Havran , Zhongqi Shen , James Bicksler , Dan Chong
发明人: Magda Asselin , George Grosu , Annmarie Sabb , Wayne Childers , Lisa Havran , Zhongqi Shen , James Bicksler , Dan Chong
IPC分类号: A61K31/496 , C07D403/14
CPC分类号: C07D403/14 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要: The present invention relates to novel piperazine-piperidine compounds. The compounds are useful as 5-HT1A binding agents, particularly as 5-HT1A receptor antagonists and agonists. These compounds are useful in treating central nervous system disorders, such as cognition disorders, anxiety disorders, depression and sexual dysfunction.
摘要翻译: 本发明涉及新的哌嗪 - 哌啶化合物。 该化合物可用作5-HT 1A结合剂,特别是5-HT 1A受体拮抗剂和激动剂。 这些化合物可用于治疗中枢神经系统疾病,如认知障碍,焦虑障碍,抑郁症和性功能障碍。
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公开(公告)号:US20050070584A1
公开(公告)日:2005-03-31
申请号:US10948611
申请日:2004-09-23
申请人: Lisa Havran , John Butera , Hassan Elokdah , Douglas Jenkins , Eric Gundersen
发明人: Lisa Havran , John Butera , Hassan Elokdah , Douglas Jenkins , Eric Gundersen
IPC分类号: A61K31/195 , A61K31/343 , A61K31/40 , A61K31/445 , A61P7/02 , C07C251/54 , C07C251/40 , C07D207/46
CPC分类号: C07D257/04 , A61K31/195 , A61K31/343 , A61K31/40 , A61K31/445 , C07C251/54
摘要: The present invention relates to substituted aryl oximes and methods of using them.
摘要翻译: 本发明涉及取代的芳基肟及其使用方法。
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