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公开(公告)号:US08383346B2
公开(公告)日:2013-02-26
申请号:US12562988
申请日:2009-09-18
申请人: Jeffrey Colbeck , Benjamin Mijts , Lorraine Joan Giver , Richard J. Fox , Vesna Mitchell , Bumshik Robert Pak , Lynne Gilson
发明人: Jeffrey Colbeck , Benjamin Mijts , Lorraine Joan Giver , Richard J. Fox , Vesna Mitchell , Bumshik Robert Pak , Lynne Gilson
CPC分类号: C12N15/1086 , C12N15/102 , C12N15/1093 , C12Q1/6876 , C40B40/06 , C40B50/06
摘要: The present disclosure relates to methods for efficient synthesis, cloning, transformation and screening of large diverse libraries of polynucleotide variants comprising well-defined nucleotide differences relative to a reference polynucleotide.
摘要翻译: 本公开涉及用于有效合成,克隆,转化和筛选多核苷酸变体的大型不同文库的方法,其包含相对于参照多核苷酸的明确的核苷酸差异。
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公开(公告)号:US08383382B2
公开(公告)日:2013-02-26
申请号:US12890134
申请日:2010-09-24
申请人: Lynne Gilson , Steven James Collier , Joly Sukumaran , Wan Lin Yeo , Oscar Alvizo , Ee Ling Teo , Robert John Wilson , Junye Xu
发明人: Lynne Gilson , Steven James Collier , Joly Sukumaran , Wan Lin Yeo , Oscar Alvizo , Ee Ling Teo , Robert John Wilson , Junye Xu
CPC分类号: C12P17/06 , C07K14/00 , C12N9/1025 , C12N9/1029 , C12N15/52 , C12P7/62 , C12Y203/01 , Y02P20/52
摘要: The present disclosure provides acyltransferases useful for synthesizing therapeutically important statin compound.
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公开(公告)号:US20110111468A1
公开(公告)日:2011-05-12
申请号:US12890134
申请日:2010-09-24
申请人: Lynne GILSON , Steven James COLLIER , Joly SUKUMARAN , Wan Lin YEO , Oscar ALVIZO , Ee Ling TEO , Robert John WILSON , Junye XU
发明人: Lynne GILSON , Steven James COLLIER , Joly SUKUMARAN , Wan Lin YEO , Oscar ALVIZO , Ee Ling TEO , Robert John WILSON , Junye XU
CPC分类号: C12P17/06 , C07K14/00 , C12N9/1025 , C12N9/1029 , C12N15/52 , C12P7/62 , C12Y203/01 , Y02P20/52
摘要: The present disclosure provides acyltransferases useful for synthesizing therapeutically important statin compound
摘要翻译: 本公开提供了可用于合成治疗重要的他汀类化合物的酰基转移酶
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