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公开(公告)号:US20120295895A1
公开(公告)日:2012-11-22
申请号:US13492193
申请日:2012-06-08
IPC分类号: A61K31/197 , A61K31/196 , A61K31/15 , A61P27/02 , A61K31/18 , A61K31/4422 , A61K31/549 , A61K31/4184 , A61K31/136 , A61K31/4985
CPC分类号: C07D487/04 , A61K9/0048 , A61K31/4162 , A61K31/4184 , A61K31/428 , A61K31/56 , C07C211/01 , C07C229/12 , C07C229/60 , C07C229/64 , C07C237/48 , C07C251/58 , C07C317/36 , C07D261/04
摘要: A method of treating an ocular disorder in a subject associated with aberrant all-trans-retinal clearance in the retina, the method comprising administering to the subject a therapeutically effective amount of a primary amine compound of formula: wherein R1 is an aliphatic and/or aromatic compound.
摘要翻译: 一种治疗与视网膜异常全反式视网膜清除相关的受试者的眼部疾病的方法,所述方法包括向受试者施用治疗有效量的下式的伯胺化合物:其中R1是脂族和/或 芳香族化合物。
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公开(公告)号:US20080275134A1
公开(公告)日:2008-11-06
申请号:US11817015
申请日:2006-02-24
摘要: A method is provided for treating a degenerative disease in a vertebrate eye. A method is further provided for preventing photoreceptor degeneration in a vertebrate eye.
摘要翻译: 提供了一种治疗脊椎动物眼中退行性疾病的方法。 进一步提供一种防止脊椎动物眼睛光感受器变性的方法。
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公开(公告)号:US08722669B2
公开(公告)日:2014-05-13
申请号:US13492193
申请日:2012-06-08
IPC分类号: A61K31/54 , A61K31/50 , A61K31/44 , A61K31/195 , A61K31/18 , A61K31/15 , A61K31/135
CPC分类号: C07D487/04 , A61K9/0048 , A61K31/4162 , A61K31/4184 , A61K31/428 , A61K31/56 , C07C211/01 , C07C229/12 , C07C229/60 , C07C229/64 , C07C237/48 , C07C251/58 , C07C317/36 , C07D261/04
摘要: A method of treating an ocular disorder in a subject associated with aberrant all-trans-retinal clearance in the retina, the method comprising administering to the subject a therapeutically effective amount of a primary amine compound of formula: wherein R1 is an aliphatic and/or aromatic compound.
摘要翻译: 一种治疗与视网膜异常全反式视网膜清除相关的受试者的眼部疾病的方法,所述方法包括向受试者施用治疗有效量的下式的伯胺化合物:其中R1是脂族和/或 芳香族化合物。
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