Methods and compositions for reducing the risk associated with the administration of opioid analgesics in patients with diagnosed or undiagnosed respiratory illness
    1.
    发明授权
    Methods and compositions for reducing the risk associated with the administration of opioid analgesics in patients with diagnosed or undiagnosed respiratory illness 失效
    用于降低诊断或未诊断呼吸系统疾病患者阿片样镇痛药相关风险的方法和组合物

    公开(公告)号:US08182837B2

    公开(公告)日:2012-05-22

    申请号:US11544187

    申请日:2006-10-06

    申请人: Maree T. Smith

    发明人: Maree T. Smith

    摘要: The present invention relates to methods for reducing the risk associated with the administration of opioid analgesics in patients diagnosed or undiagnosed with respiratory illness by administering an analgesic composition comprising a sub-analgesic dosage of a p-opioid agonist selected from the group consisting of morphine, fentanyl, sufentanil, alfentanil, oxymorphone and hydromorphone, or a pharmaceutically acceptable salt thereof, and a sub-analgesic dosage of oxycodone which is a κ2-opioid agonist or a pharmaceutically acceptable salt thereof.

    摘要翻译: 本发明涉及通过施用镇痛组合物来降低与诊断或未诊断为呼吸系统疾病的患者中阿片样镇痛药相关的风险的方法,所述镇痛组合物包含选自吗啡的对 - 阿片样物质激动剂的次镇痛剂量, 芬太尼,舒芬太尼,阿芬太尼,羟吗啡酮和氢吗啡酮,或其药学上可接受的盐,以及作为阿片样物质激动剂或其药学上可接受的盐的羟考酮的次镇痛剂量。

    METHODS AND COMPOSITIONS FOR REDUCING THE RISK ASSOCIATED WITH THE ADMINISTRATION OF OPIOID ANALGESICS IN PATIENTS DIAGNOSED OR UNDIAGNOSED RESPIRATORY ILLNESS
    2.
    发明申请
    METHODS AND COMPOSITIONS FOR REDUCING THE RISK ASSOCIATED WITH THE ADMINISTRATION OF OPIOID ANALGESICS IN PATIENTS DIAGNOSED OR UNDIAGNOSED RESPIRATORY ILLNESS 审中-公开
    方法和组合物,用于降低与诊断或不良反应无效的患者中的阿片类药物治疗相关的风险

    公开(公告)号:US20120316189A1

    公开(公告)日:2012-12-13

    申请号:US13444073

    申请日:2012-04-11

    IPC分类号: A61K31/485 A61P25/04

    摘要: The present invention relates to methods for reducing the risk associated with the administration of opioid analgesics in patient diagnosed or undiagnosed with respiratory illness by administering an analgesic composition comprising a sub-analgesic dosage of a p-opioid agonist selected from the group consisting a morphine, fentanyl, sufentanil, alfentanil, oxymorphone and hydromorphone, or a pharmaceutically acceptable salt thereof, and a sub-analgesic dosage of oxycodone which is a κ2-opioid agonist or a pharmaceutically acceptable salt thereof.

    摘要翻译: 本发明涉及通过施用镇痛组合物来降低与诊断或未诊断为呼吸系统疾病的患者中阿片样镇痛药相关的风险的方法,所述止痛组合物包含选自以下组中的β-阿片样物质激动剂的亚类镇痛剂:吗啡, 芬太尼,舒芬太尼,阿芬太尼,羟吗啡酮和氢吗啡酮,或其药学上可接受的盐,以及作为阿片样物质激动剂或其药学上可接受的盐的羟考酮的次镇痛剂量。