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公开(公告)号:US20060035315A1
公开(公告)日:2006-02-16
申请号:US10203486
申请日:2001-02-23
申请人: Henry Yue , Y Tang , Preeti Lal , Jennifer Policky , Danniel Nguyen , Janice Au-Young , Monique Yao , Farrah Khan , Narinder Walia , Ameena Gandhi , Catherine Tribouley , Chandra Arvizu , Michael Thornton , Barrie Greene , Roberto Hernandez , Mark Borowsky , Madhu Sanjanwala
发明人: Henry Yue , Y Tang , Preeti Lal , Jennifer Policky , Danniel Nguyen , Janice Au-Young , Monique Yao , Farrah Khan , Narinder Walia , Ameena Gandhi , Catherine Tribouley , Chandra Arvizu , Michael Thornton , Barrie Greene , Roberto Hernandez , Mark Borowsky , Madhu Sanjanwala
IPC分类号: C07K14/705 , C07H21/04 , C12P21/06 , C12N15/74
CPC分类号: C07K14/705 , A61K38/00
摘要: The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
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公开(公告)号:US20050123912A1
公开(公告)日:2005-06-09
申请号:US10486977
申请日:2002-08-14
申请人: Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
发明人: Ines Barroso , Mariah Baughn , Shanya Becha , Julie Blake , Mark Borowsky , Neil Burford , Brendan Duggan , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Cynthia Honchell , Craig Ison , Farrah Khan , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joana Li , Dyung Lu , Yan Lu , Patricia Lehr-Mason , Danniel Nguyen , Jayalaxmi Ramkumar , William Sprague , Y Tang , Kavitha Thangavelu , Michael Thornton , Uyen Tran , Narinder Chawla , Bridget Warren , Yuming Xu , Monique Yao , Henry Yue , Huibin Yue , Yeganeh Zebarjadian
IPC分类号: G01N33/50 , A61K38/00 , A61K45/00 , A61K49/00 , A61P1/00 , A61P1/16 , A61P3/10 , A61P7/00 , A61P9/00 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/00 , A61P15/00 , A61P17/00 , A61P17/06 , A61P19/00 , A61P19/02 , A61P19/06 , A61P19/10 , A61P21/00 , A61P25/00 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07K14/47 , C07K16/18 , C12M1/00 , C12M1/34 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/02 , C12N15/09 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N37/00 , C07H21/04 , C12N9/22
CPC分类号: C07K14/4702 , A61K38/00 , G01N2500/00
摘要: Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译: 本发明的各种实施方案提供了识别和编码NAAP的人核酸相关蛋白(NAAP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与NAAP异常表达相关的紊乱的方法。
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3.
公开(公告)号:US20060216706A1
公开(公告)日:2006-09-28
申请号:US10484603
申请日:2002-07-16
申请人: Y Tang , Vicki Elliott , Mariah Baughn , Henry Yue , Aaron Klammer , April Hafalia , Elizabeth Stewart , Cynthia Honchell , Ann Gorvard , Ian Forsythe , Li Ding , Uyen Tran , Jennifer Griffin , Yeganeh Zebarjadian , Anna Chinn , Anne Curtis , Mark Borowsky , Anita Swarnakar , Neil Burford , Wen Luo , Ernestine Lee , Brooke Emerling , Soo Lee , Junming Yang , Farrah Khan , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla , Brendan Duggan , Kimberly Gietzen , Karen Jones
发明人: Y Tang , Vicki Elliott , Mariah Baughn , Henry Yue , Aaron Klammer , April Hafalia , Elizabeth Stewart , Cynthia Honchell , Ann Gorvard , Ian Forsythe , Li Ding , Uyen Tran , Jennifer Griffin , Yeganeh Zebarjadian , Anna Chinn , Anne Curtis , Mark Borowsky , Anita Swarnakar , Neil Burford , Wen Luo , Ernestine Lee , Brooke Emerling , Soo Lee , Junming Yang , Farrah Khan , Jayalaxmi Ramkumar , Yan Lu , Narinder Chawla , Brendan Duggan , Kimberly Gietzen , Karen Jones
IPC分类号: C12Q1/68 , G01N33/574 , C07H21/04 , C12P21/06 , C07K14/705
CPC分类号: C07K14/47 , C12Q1/6883 , C12Q1/6886 , C12Q2600/136 , G01N33/574 , G01N2510/00
摘要: Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译: 本发明的各种实施方案提供与细胞生长,分化和死亡(CGDD)相关的人类蛋白质和鉴定和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与CGDD异常表达相关的紊乱的方法。
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公开(公告)号:US20060035331A1
公开(公告)日:2006-02-16
申请号:US11190188
申请日:2005-07-27
申请人: Preeti Lal , Y. Tang , Chandra Arvizu , Monique Yao , Leo Shih , Catherine Tribouley , Dyung Aina Lu , Henry Yue , Farrah Khan , Jennifer Policky , Janice Au-Young , Junming Yang , Lee Harland , Roderick Walsh , Terence Lo , Mark Borowsky
发明人: Preeti Lal , Y. Tang , Chandra Arvizu , Monique Yao , Leo Shih , Catherine Tribouley , Dyung Aina Lu , Henry Yue , Farrah Khan , Jennifer Policky , Janice Au-Young , Junming Yang , Lee Harland , Roderick Walsh , Terence Lo , Mark Borowsky
IPC分类号: C07H21/04 , C12P21/06 , C07K14/705
CPC分类号: C07K14/705 , A01K2217/05 , A61K38/00
摘要: The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
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公开(公告)号:US20050191690A1
公开(公告)日:2005-09-01
申请号:US11100583
申请日:2005-04-07
申请人: Preeti Lal , Mariah Baughn , April Hafalia , Danniel Nguyen , Ameena Gandhi , Deborah Kallick , Jennifer Griffin , Henry Yue , Farrah Khan , Chandra Arvizu , Dyung M. Lu , Catherine Tribouley , Yan Lu , Narinder Chawla , Richard Graul , Monique Yao , Junming Yang , Jayakaxmi Ramkumar , Janice Au-Young , Vicki Elliott , Roberto Hernandez , Roderick Walsh , Mark Borowsky , Michael Thornton , Ann He
发明人: Preeti Lal , Mariah Baughn , April Hafalia , Danniel Nguyen , Ameena Gandhi , Deborah Kallick , Jennifer Griffin , Henry Yue , Farrah Khan , Chandra Arvizu , Dyung M. Lu , Catherine Tribouley , Yan Lu , Narinder Chawla , Richard Graul , Monique Yao , Junming Yang , Jayakaxmi Ramkumar , Janice Au-Young , Vicki Elliott , Roberto Hernandez , Roderick Walsh , Mark Borowsky , Michael Thornton , Ann He
IPC分类号: G01N33/50 , A61K31/7088 , A61K38/00 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/00 , A61P3/00 , A61P9/00 , A61P25/00 , A61P31/00 , A61P35/00 , A61P37/00 , A61P43/00 , C07K14/705 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号: C07K14/705 , A61K38/00
摘要: The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
摘要翻译: 本发明提供鉴定和编码GCREC的人G-蛋白偶联受体(GCREC)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与GCREC异常表达相关的疾病的方法。
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6.
公开(公告)号:US20050048490A1
公开(公告)日:2005-03-03
申请号:US10491213
申请日:2002-09-26
申请人: Yalda Azimzai , Mariah Baughn , Shanya Becha , Mark Borowsky , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ameena Gandhi , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Amu Kable , Daniel Kalafus , Patircia Lehr-Mason , Dyung Aina Lu , Joseph Marquis , Danniel Nguyen , Jayalaxmi Ramkumar , Thomas Richardson , Stephanie Kareht , Anita Swarnakar , Y Tom Tang , Uyen Tran , Bridget Warren , Yuming Xu , Monique Yao , Huibin Yue , Henry Yue
发明人: Yalda Azimzai , Mariah Baughn , Shanya Becha , Mark Borowsky , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ameena Gandhi , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Amu Kable , Daniel Kalafus , Patircia Lehr-Mason , Dyung Aina Lu , Joseph Marquis , Danniel Nguyen , Jayalaxmi Ramkumar , Thomas Richardson , Stephanie Kareht , Anita Swarnakar , Y Tom Tang , Uyen Tran , Bridget Warren , Yuming Xu , Monique Yao , Huibin Yue , Henry Yue
CPC分类号: G01N33/74 , C07H21/04 , C07K14/4747 , G01N2500/00
摘要: Various embodiments of the invention provide human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides whichidentify and encode CGDD. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
摘要翻译: 本发明的各种实施方案提供与细胞生长,分化和死亡(CGDD)相关的人类蛋白质和识别和编码CGDD的多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与CGDD异常表达相关的紊乱的方法。
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7.RAPID PHENOTYPIC DIAGNOSIS OF PATHOGENS AND DRUG RESISTANCE USING TRANSCRIPTIONAL EXPRESSION SIGNATURES 有权
标题翻译: 使用转录表达标记快速诊断病原体和药物耐药性公开(公告)号:US20130190196A1
公开(公告)日:2013-07-25
申请号:US13580618
申请日:2011-02-24
申请人: Andrew B. Onderdonk , Amy Barczak , Deborah Hung , James Gomez , Lisa Cosimi , Rob Nicol , Mark Borowsky
发明人: Andrew B. Onderdonk , Amy Barczak , Deborah Hung , James Gomez , Lisa Cosimi , Rob Nicol , Mark Borowsky
CPC分类号: C12Q1/689 , C12Q1/025 , C12Q1/6809 , C12Q1/6888 , C12Q1/6895 , C12Q1/70 , C12Q2600/112 , C12Q2600/158 , G01N2333/35 , G01N2800/52 , G01N2800/56
摘要: The specification relates generally to methods of detecting, diagnosing, and/or identifying pathogens, e.g., infectious disease pathogens and determining their drug sensitivity and appropriate methods of treatment. This invention also relates generally to methods of monitoring pathogen infection in individual subjects as well as larger populations of subjects.
摘要翻译: 本说明书一般涉及检测,诊断和/或鉴定病原体,例如感染性疾病病原体并确定其药物敏感性和适当的治疗方法的方法。 本发明一般还涉及监测个体受试者以及更大群体受试者的病原体感染的方法。
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公开(公告)号:US20050239126A1
公开(公告)日:2005-10-27
申请号:US11167040
申请日:2005-06-27
申请人: Stephen Todd , Angelo Delegeane , Ameena Gandhi , Danniel Nguyen , April Hafalia , Liam Kearney , Yan Lu , Ernestine Lee , Narinder Chawla , Debopriya Das , Chandra Arvizu , Monique Yao , Deborah Kallick , Vicki Elliott , Li Ding , Henry Yue , Roopa Reddy , Dyung Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine Tribouley , Neil Burford , Mariah Baughn , Preeti Lal , Mark Borowsky , Farrah Khan , Rajagopal Gururajan , Y. Tang , Janice Au-Young , Bridget Warren , Roberto Hernandez , Brendan Duggan
发明人: Stephen Todd , Angelo Delegeane , Ameena Gandhi , Danniel Nguyen , April Hafalia , Liam Kearney , Yan Lu , Ernestine Lee , Narinder Chawla , Debopriya Das , Chandra Arvizu , Monique Yao , Deborah Kallick , Vicki Elliott , Li Ding , Henry Yue , Roopa Reddy , Dyung Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine Tribouley , Neil Burford , Mariah Baughn , Preeti Lal , Mark Borowsky , Farrah Khan , Rajagopal Gururajan , Y. Tang , Janice Au-Young , Bridget Warren , Roberto Hernandez , Brendan Duggan
CPC分类号: C12N9/6421 , A01K2217/05 , A01K2217/075 , C07H21/04 , C12N9/6472 , C12Q1/6837 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , Y02A50/52
摘要: The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
摘要翻译: 本发明提供鉴定和编码PRTS的人类蛋白酶(PRTS)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供诊断,治疗或预防与PRTS异常表达相关的疾病的方法。
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公开(公告)号:US20050186569A1
公开(公告)日:2005-08-25
申请号:US10491472
申请日:2002-10-29
申请人: Shanya Becha , Mark Borowsky , Neil Burford , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joseph Marquis , Jayalaxmi Ramkumar , William Sprague , Anita Swarnakar , Y. Tang , Bridget Warren , Junming Yang , Henry Yue , Yeganeh Zebarjadian
发明人: Shanya Becha , Mark Borowsky , Neil Burford , Narinder Chawla , Vicki Elliott , Brooke Emerling , Ian Forsythe , Kimberly Gietzen , Ann Gorvad , Jennifer Griffin , April Hafalia , Craig Ison , Preeti Lal , Ernestine Lee , Sally Lee , Soo Lee , Joseph Marquis , Jayalaxmi Ramkumar , William Sprague , Anita Swarnakar , Y. Tang , Bridget Warren , Junming Yang , Henry Yue , Yeganeh Zebarjadian
CPC分类号: C07K14/4702 , C07K14/47
摘要: A Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
摘要翻译: 本发明的各种实施方案提供鉴定和编码NAAP的人核酸相关蛋白(NAAP)和多核苷酸。 本发明的实施方案还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 其他实施方案提供用于诊断,治疗或预防与NAAP异常表达相关的紊乱的方法。
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公开(公告)号:US20050142600A1
公开(公告)日:2005-06-30
申请号:US11046868
申请日:2005-02-01
申请人: Bridget Warren , Cynthia Honchell , Yan Lu , Narinder Chawla , Neil Burford , Angelo Delegeane , Ameena Gandhi , Mariah Baughn , Jennifer Griffin , Kimberly Gietzen , Dyung Lu , Craig Ison , Jayalaxmi Ramkumar , Y. Tang , Preeti Lal , Mark Borowsky , Brendan Duggan , April Hafalia , Chandra Arvizu , Kavitha Thangavelu , Monique Yao , Vicki Elliott , Li Ding , Henry Yue , Sally Lee , Anita Swarnakar , Uyen Tran , Yuming Xu
发明人: Bridget Warren , Cynthia Honchell , Yan Lu , Narinder Chawla , Neil Burford , Angelo Delegeane , Ameena Gandhi , Mariah Baughn , Jennifer Griffin , Kimberly Gietzen , Dyung Lu , Craig Ison , Jayalaxmi Ramkumar , Y. Tang , Preeti Lal , Mark Borowsky , Brendan Duggan , April Hafalia , Chandra Arvizu , Kavitha Thangavelu , Monique Yao , Vicki Elliott , Li Ding , Henry Yue , Sally Lee , Anita Swarnakar , Uyen Tran , Yuming Xu
CPC分类号: C12N9/6421 , A01K2217/05 , A61K38/00 , C07H21/04 , C12N9/64
摘要: The invention provides human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.
摘要翻译: 本发明提供了鉴定和编码PMMM的人蛋白质修饰和维持分子(PMMM)和多核苷酸。 本发明还提供表达载体,宿主细胞,抗体,激动剂和拮抗剂。 本发明还提供用于诊断,治疗或预防与PMMM的异常表达相关的紊乱的方法。
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