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    Providing information about mobile communication devices
    1.
    发明授权
    Providing information about mobile communication devices 有权
    提供有关移动通信设备的信息

    公开(公告)号：US09125008B2

    公开(公告)日：2015-09-01

    申请号：US13183298

    申请日：2011-07-14

    申请人： Mark Nichols ,  Gregory C. Best

    发明人： Mark Nichols ,  Gregory C. Best

    IPC分类号： G08B1/08 ,  H04W4/02 ,  H04W64/00 ,  H04W4/12

    CPC分类号： H04W4/02 ,  H04W4/12 ,  H04W64/00

    摘要： A method and system for providing information about mobile communication devices with respect to an area of interest is disclosed. A first person associated with the mobile communication device located in the area of interest is identified, wherein the identifying occurs at a location and messaging center. A contact person associated with the first person is identified. Information is provided to the contact person that the mobile communication device associated with the first person is located in the area of interest.

    摘要翻译： 公开了一种用于提供关于移动通信设备关于感兴趣区域的信息的方法和系统。 识别与位于感兴趣区域中的移动通信设备相关联的第一人，其中识别发生在位置和消息中心。 识别与第一人员相关联的联系人。 向联系人提供与第一人员相关联的移动通信设备位于感兴趣区域中的信息。

    METHOD AND SYSTEM FOR CONTROLLING AN EXCAVATOR
    2.
    发明申请
    METHOD AND SYSTEM FOR CONTROLLING AN EXCAVATOR 有权
    用于控制挖掘机的方法和系统

    公开(公告)号：US20130333364A1

    公开(公告)日：2013-12-19

    申请号：US13527095

    申请日：2012-06-19

    申请人： Hamish John Carpenter ,  Richard Paul Piekutowski ,  Mark Nichols

    发明人： Hamish John Carpenter ,  Richard Paul Piekutowski ,  Mark Nichols

    IPC分类号： F15B3/00

    CPC分类号： F15B3/00 ,  E02F3/435 ,  E02F9/2029 ,  E02F9/2203 ,  E02F9/265

    摘要： A control for an excavator of the type having a plurality of hydraulic cylinders for moving excavator components such that digging is accomplished at a worksite with an excavator bucket or other excavator implement, includes a plurality of hydraulic control valves, each of which is associated with a respective one of the hydraulic cylinders for controlling the application of hydraulic fluid pressure to the respective one of the hydraulic cylinders, and a plurality of manually actuated joystick valves for supplying hydraulic fluid pressure to the respective hydraulic control valves to control the movement of the hydraulic cylinders. The control includes a sensor arrangement for sensing the position of one or more excavator components.

    摘要翻译： 具有多个用于移动挖掘机部件的挖掘机的挖掘机的控制装置包括多个液压控制阀，每个液压控制阀与一个液压控制阀相关联，该多个液压缸与挖掘机铲斗或其他挖掘机工具在工地上完成挖掘 用于控制对相应的一个液压缸施加液压流体压力的液压缸中的相应一个;以及用于向相应的液压控制阀提供液压流体压力以控制液压缸的运动的多个手动操作的操纵杆阀 。 该控制器包括用于感测一个或多个挖掘机部件的位置的传感器装置。

    Loader and loader control system
    3.
    发明授权
    Loader and loader control system 有权

    公开(公告)号：US07881845B2

    公开(公告)日：2011-02-01

    申请号：US11959722

    申请日：2007-12-19

    申请人： Mark Nichols

    发明人： Mark Nichols

    IPC分类号： E02F9/26 ,  G01C21/00 ,  G06F19/00

    CPC分类号： E02F3/3414 ,  E02F3/431 ,  E02F9/264

    摘要： A loader and a control system for a loader provide for monitoring the position of a part of the implement carried by the loader. The loader has a body with left and right upright tower portions, and a loader drive system including ground engaging drive elements. Left and right interconnected lift arm assemblies each have an implement lift arm pivotally connected with a corresponding tower portion of the body at a lift arm pivot point. A lift actuator is connected between the body and the lift arm. The implement is pivotally connected with the lift arm assemblies about an implement pivot axis. The lift arm pivot point and the implement pivot axis in side elevation define a straight reference line. At least one implement tilt actuator is connected between at least one of the lift arm assemblies and the implement. A position sensor is mounted on the body at the level of, or above, the lift arm pivot points. An inclinometer is movable with the left and right interconnected lift arm assemblies to provide an indication of the inclination of the lift arm assemblies along the straight reference line. An angle sensor provides an indication of the orientation of said implement with respect to said left and right interconnected lift arm assemblies. The control is responsive to the position sensor, the inclinometer, and the angle sensor. The control determines the position of the position sensor and the position of a part of the implement with respect to the position sensor.

    METHOD AND SYSTEM FOR ADAPTIVE CONSTRUCTION SEQUENCING
    4.
    发明申请
    METHOD AND SYSTEM FOR ADAPTIVE CONSTRUCTION SEQUENCING 审中-公开
    自适应结构测序方法与系统

    公开(公告)号：US20100217640A1

    公开(公告)日：2010-08-26

    申请号：US12390356

    申请日：2009-02-20

    申请人： Mark NICHOLS

    发明人： Mark NICHOLS

    IPC分类号： G06Q10/00 ,  G06F17/50 ,  G06Q50/00 ,  G06Q30/00

    CPC分类号： G06Q10/06313 ,  G06Q10/04 ,  G06Q10/06 ,  G06Q10/0631 ,  G06Q30/0283 ,  G06Q50/08

    摘要： A computer implemented method and computer system for adaptive construction sequencing. In one embodiment, a scheduling component is used to access a schedule for completing a project is. A 3-dimensional (3-D) simulation component is used to generate a 3-D model of at least one component used in completing the project. The 3-D simulation component is used to generate a 3-D simulation showing the construction of the project in accordance with the schedule. A cost estimating component is used to generate a cost estimate of the cost of completing the project in accordance with the schedule.

    摘要翻译： 一种用于自适应构建排序的计算机实现方法和计算机系统。 在一个实施例中，调度组件用于访问用于完成项目的调度。 三维（3-D）模拟组件用于生成用于完成项目的至少一个组件的3-D模型。 3-D模拟组件用于生成按照时间表显示项目建设的3-D模拟。 成本估算部分用于按照时间表生成完成项目成本的成本估算。

    Small interfering RNA libraries and methods of synthesis and use
    5.
    发明授权
    Small interfering RNA libraries and methods of synthesis and use 失效
    小干扰RNA文库和合成和使用方法

    公开(公告)号：US07524653B2

    公开(公告)日：2009-04-28

    申请号：US10842353

    申请日：2004-05-10

    申请人： Mark Nichols ,  Richard Steinman

    发明人： Mark Nichols ,  Richard Steinman

    IPC分类号： C12N15/64 ,  C12N15/00 ,  C07H21/04

    CPC分类号： C12N15/1138 ,  C12N15/1093 ,  C12N15/111 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2330/31

    摘要： In one aspect, the invention provides a random or semirandom siRNA (encoding) library. Another aspect of the invention pertains to methods for construction of random or semirandom siRNA (encoding) libraries. Another aspect of the invention is vector systems for use in constructing siRNA libraries and/or that can express single siRNAs and siRNA libraries both constitutively and in an inducible fashion. In another aspect, the invention provides a method of using an siRNA library. The siRNA library is introduced into a population of cells. The population of cells then is subjected to a selection process to select a subpopulation of cells exhibiting a different behavioral, biochemical, chemical, functional, molecular, morphological, phenotypic, or physical property from the remainder of population. Following the selection process, the subpopulation of cells can be isolated, analyzed, and/or cloned as desired. Such analysis of the subpopulation can be identification and sequencing of the siRNA species responsible for the different properties of the subpopulation relative to the remainder of the population. Alternatively, the subpopulation can be further analyzed by genomic, proteomic, and/or cellomic assays. Where such genomic, proteomic, and/or cellomic assays are employed, the method can produce several useful bioinformatics products. Specific siRNAs identified through this process may have direct therapeutic value.

    摘要翻译： 一方面，本发明提供了随机或半免疫siRNA（编码）文库。 本发明的另一方面涉及用于构建随机或半随机siRNA（编码）文库的方法。 本发明的另一方面是用于构建siRNA文库的载体系统和/或可组成型和诱导型表达单个siRNA和siRNA文库。 另一方面，本发明提供了使用siRNA文库的方法。 将siRNA文库导入细胞群。 然后对细胞群体进行选择过程，从其余群体中选择表现出不同行为，生物化学，化学，功能，分子，形态，表型或物理性质的细胞亚群。 在选择过程之后，可以根据需要分离，分析和/或克隆细胞亚群。 亚群的这种分析可以是负责亚群相对于其余群体的不同性质的siRNA物种的鉴定和测序。 或者，亚群可以通过基因组，蛋白质组学和/或纤维素测定进一步分析。 在使用这种基因组，蛋白质组学和/或纤维素测定法的情况下，该方法可以产生几种有用的生物信息学产物。 通过该方法鉴定的特异性siRNA可具有直接的治疗价值。

    Small interfering RNA libraries and methods of synthesis and use
    8.
    发明申请
    Small interfering RNA libraries and methods of synthesis and use 失效
    小干扰RNA文库和合成和使用方法

    公开(公告)号：US20070166720A1

    公开(公告)日：2007-07-19

    申请号：US10842353

    申请日：2004-05-10

    申请人： Mark Nichols ,  Richard Steinman

    发明人： Mark Nichols ,  Richard Steinman

    IPC分类号： C40B30/06 ,  C40B40/08

    CPC分类号： C12N15/1138 ,  C12N15/1093 ,  C12N15/111 ,  C12N2310/111 ,  C12N2310/14 ,  C12N2310/53 ,  C12N2330/31

    摘要： In one aspect, the invention provides a random or semirandom siRNA (encoding) library. Another aspect of the invention pertains to methods for construction of random or semirandom siRNA (encoding) libraries. Another aspect of the invention is vector systems for use in constructing siRNA libraries and/or that can express single siRNAs and siRNA libraries both constitutively and in an inducible fashion. In another aspect, the invention provides a method of using an siRNA library. The siRNA library is introduced into a population of cells. The population of cells then is subjected to a selection process to select a subpopulation of cells exhibiting a different behavioral, biochemical, chemical, functional, molecular, morphological, phenotypic, or physical property from the remainder of population. Following the selection process, the subpopulation of cells can be isolated, analyzed, and/or cloned as desired. Such analysis of the subpopulation can be identification and sequencing of the siRNA species responsible for the different properties of the subpopulation relative to the remainder of the population. Alternatively, the subpopulation can be further analyzed by genomic, proteomic, and/or cellomic assays. Where such genomic, proteomic, and/or cellomic assays are employed, the method can produce several useful bioinformatics products. Specific siRNAs identified through this process may have direct therapeutic value.

    摘要翻译： 一方面，本发明提供了随机或半免疫siRNA（编码）文库。 本发明的另一方面涉及用于构建随机或半随机siRNA（编码）文库的方法。 本发明的另一方面是用于构建siRNA文库的载体系统和/或可组成型和诱导型表达单个siRNA和siRNA文库。 另一方面，本发明提供了使用siRNA文库的方法。 将siRNA文库导入细胞群。 然后对细胞群体进行选择过程，从其余群体中选择表现出不同行为，生物化学，化学，功能，分子，形态，表型或物理性质的细胞亚群。 在选择过程之后，可以根据需要分离，分析和/或克隆细胞亚群。 亚群的这种分析可以是负责亚群相对于其余群体的不同性质的siRNA物种的鉴定和测序。 或者，亚群可以通过基因组，蛋白质组学和/或纤维素测定进一步分析。 在使用这种基因组，蛋白质组学和/或纤维素测定法的情况下，该方法可以产生几种有用的生物信息学产物。 通过该方法鉴定的特异性siRNA可具有直接的治疗价值。

    Method for augmenting radio positioning system using single fan laser
    10.
    发明申请
    Method for augmenting radio positioning system using single fan laser 有权
    使用单扇激光器增强无线电定位系统的方法

    公开(公告)号：US20070058161A1

    公开(公告)日：2007-03-15

    申请号：US11214221

    申请日：2005-08-27

    申请人： Mark Nichols ,  Nicholas Talbot ,  Gary Cain

    发明人： Mark Nichols ,  Nicholas Talbot ,  Gary Cain

    IPC分类号： G01C1/00 ,  G01B11/26

    CPC分类号： G01S19/04 ,  G01S19/07 ,  G01S19/10 ,  G01S19/44 ,  G01S19/46

    摘要： A method of augmenting a mobile radio positioning system (Mobile_RADPS) by using a stationary fan laser transmitter. A rover comprises the mobile radio positioning system (Mobile_RADPS) integrated with a mobile laser detector. The stationary fan laser transmitter is integrated with a stationary radio positioning system (Stationary_RADPS). The method comprises the following steps: (A)generating a single sloping fan beam by the stationary fan laser transmitter; (B) detecting the single sloping fan beam generated by the stationary fan laser transmitter by using the mobile laser detector; and (C) timing the fan laser beam strike at the rover's location and using the timing of the fan laser beam strike at the rover's location to improve an accuracy in determination of position coordinates of the rover.

    摘要翻译： 一种通过使用固定式风扇激光发射器来增强移动无线电定位系统（Mobile_RADPS）的方法。 流动站包括与移动激光检测器集成的移动无线电定位系统（Mobile_RADPS）。 固定式风扇激光发射机与固定无线电定位系统（Stationary_RADPS）集成。 该方法包括以下步骤：（A）由固定式风扇激光发射器产生单个倾斜扇形光束; （B）使用移动式激光检测器检测由固定式风扇激光发射器产生的单斜扇形光束; 并且（C）使风扇激光束在流动站的位置处定时，并且使用风扇激光束在流动站的位置处的打击时间来提高确定流动站的位置坐标的准确度。