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公开(公告)号:US20110091379A1
公开(公告)日:2011-04-21
申请号:US12901399
申请日:2010-10-08
申请人: Franz Paul ARMBRUSTER , Markus Karmatschek , Franz Werner Nader , Ulf Joerg Forssmann , Mats Paulsson , Martin R. Berger
发明人: Franz Paul ARMBRUSTER , Markus Karmatschek , Franz Werner Nader , Ulf Joerg Forssmann , Mats Paulsson , Martin R. Berger
IPC分类号: A61K39/395 , A61K51/10 , A61K9/14 , A61P35/00
CPC分类号: C07K16/18 , A01K2217/05 , A61K2039/505 , C07K14/51 , C07K2317/11 , C07K2317/21
摘要: The invention relates to a medicament against tumors and their metastases, which preferentially settle in bone tissue, comprising active ingredient at least one binding molecule that binds to bone sialoprotein or a fragment thereof in serum or plasma.
摘要翻译: 本发明涉及一种抗肿瘤及其转移的药物,其优先沉降于骨组织中,其包含活性成分与血清或血浆中骨涎蛋白或其片段结合的至少一种结合分子。
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公开(公告)号:US08808691B2
公开(公告)日:2014-08-19
申请号:US12901399
申请日:2010-10-08
申请人: Franz Paul Armbruster , Markus Karmatschek , Franz Werner Nader , Ulf Joerg Forssmann , Mats Paulsson , Martin R. Berger
发明人: Franz Paul Armbruster , Markus Karmatschek , Franz Werner Nader , Ulf Joerg Forssmann , Mats Paulsson , Martin R. Berger
IPC分类号: A61K39/395
CPC分类号: C07K16/18 , A01K2217/05 , A61K2039/505 , C07K14/51 , C07K2317/11 , C07K2317/21
摘要: The invention relates to a method of therapy against tumors and their metastases, which preferentially settle in bone tissue, comprising administering to a patient in need thereof an active ingredient which comprises at least one binding molecule that binds to human bone sialoprotein or a fragment thereof.
摘要翻译: 本发明涉及一种针对肿瘤及其转移的治疗方法,其优先沉降于骨组织中,包括向有需要的患者施用包含至少一种结合人骨涎蛋白或其片段的结合分子的活性成分。
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公开(公告)号:US07825219B2
公开(公告)日:2010-11-02
申请号:US10480465
申请日:2002-06-12
申请人: Franz Paul Armbruster , Markus Karmatschek , Franz Werner Nader , Ulf Joerg Forssmann , Mats Paulsson , Martin R. Berger
发明人: Franz Paul Armbruster , Markus Karmatschek , Franz Werner Nader , Ulf Joerg Forssmann , Mats Paulsson , Martin R. Berger
IPC分类号: C07K16/00 , A61K39/395 , A61K43/00
CPC分类号: C07K16/18 , A01K2217/05 , A61K2039/505 , C07K14/51 , C07K2317/11 , C07K2317/21
摘要: The invention relates to a medicament against tumors and their metastases, which preferentially settle in bone tissue, comprising as active ingredient at least one binding molecule which binds to bone sialoprotein or a fragment thereof in serum or plasma.
摘要翻译: 本发明涉及一种抗肿瘤及其转移的药物,其优先沉降于骨组织中,其包含与血清或血浆中的骨唾液酸蛋白或其片段结合的至少一种结合分子作为活性成分。
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