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公开(公告)号：US09150555B2
公开(公告)日：2015-10-06
申请号：US13879475
申请日：2011-10-13
Applicant: Hiroyuki Ushio , Maiko Hamada , Masayuki Watanabe , Atsushi Numata , Naoto Fujie , Tooru Takashima , Hiroyuki Furukawa , Junki Ando
Inventor： Hiroyuki Ushio , Maiko Hamada , Masayuki Watanabe , Atsushi Numata , Naoto Fujie , Tooru Takashima , Hiroyuki Furukawa , Junki Ando
IPC: A61K31/47 , C07D211/14 , C07D405/14 , C07D401/12 , C07D401/14 , C07D405/12 , C07D417/12 , C07D495/04
CPC classification number: C07D405/14 , C07D401/12 , C07D401/14 , C07D405/12 , C07D417/12 , C07D495/04
Abstract: The present invention relates to a novel amide derivative. More specifically, the present invention provides a medicinal agent useful as a prophylactic or therapeutic agent for diseases, which relies on the production of cytokines from T cells, and which comprises an amide derivative or a pharmacologically acceptable salt thereof or a solvate of the derivative or the pharmacologically acceptable salt as an active ingredient. Provided is an amide derivative represented by general formula (I) [wherein each symbol is as defined in the description] or a pharmacologically acceptable salt thereof, or a solvate of the derivative or the pharmacologically acceptable salt.
Abstract translation: 本发明涉及新型酰胺衍生物。 更具体地说，本发明提供可用作疾病的预防或治疗剂的药剂，其依赖于来自T细胞的细胞因子的产生，并且其包含酰胺衍生物或其药理学上可接受的盐或衍生物的溶剂合物或 药理学上可接受的盐作为活性成分。 本发明提供通式（I）表示的酰胺衍生物或其药理学上可接受的盐，或其衍生物或药理学上可接受的盐的溶剂合物。
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公开(公告)号：US08852868B2
公开(公告)日：2014-10-07
申请号：US13643986
申请日：2011-02-02
Applicant: Tetsuo Ohashi , Masayuki Watanabe
Inventor： Tetsuo Ohashi , Masayuki Watanabe
IPC: C12Q1/68
CPC classification number: C12Q1/686 , C12Q2527/101 , C12Q2527/15 , C12Q2561/113 , C12Q2563/143 , C12Q2563/159
Abstract: The present invention provides a real time nucleic acid amplification reaction method comprising performing a nucleic acid amplification reaction in a droplet present in a container. The droplet is composed of a nucleic acid amplification reaction liquid including a nucleic acid to be amplified and magnetic particles. The container holds a droplet encapsulating medium immiscible with the nucleic acid amplification reaction liquid forming the droplet, and has a transport surface having a temperature gradient. Fluorochrome is initially contained in the droplet encapsulating medium, and optionally in the droplet, at start of the nucleic acid amplification reaction. The droplet is transported together with the magnetic particles by generating and applying a magnetic field so that the droplet is placed on the transport surface at a temperature point at which the nucleic acid synthesis reaction is started and maintained, thereby controlling a temperature of the reaction liquid.
Abstract translation: 本发明提供了一种实时核酸扩增反应方法，包括在存在于容器中的液滴中进行核酸扩增反应。 液滴由包含待扩增的核酸和磁性颗粒的核酸扩增反应液组成。 容器容纳与形成液滴的核酸扩增反应液不混溶的液滴封装介质，并具有温度梯度的输送面。 在核酸扩增反应开始时，荧光染料最初包含在液滴包封介质中，并且任选地包含在液滴中。 通过产生和施加磁场使液滴与磁性颗粒一起输送，使得液滴在开始和维持核酸合成反应的温度点放置在输送表面上，从而控制反应液体的温度 。
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公开(公告)号：US08597326B2
公开(公告)日：2013-12-03
申请号：US12521928
申请日：2007-12-27
Applicant: Kanji Matsutani , Yoshimasa Tochimura , Masayuki Watanabe , Shinichi Akutsu
Inventor： Kanji Matsutani , Yoshimasa Tochimura , Masayuki Watanabe , Shinichi Akutsu
IPC: A61B17/06
CPC classification number: A61B17/06066 , A61B17/062 , A61B2017/00429 , A61B2017/00526 , A61B2017/06071 , A61B2017/06085 , B21G1/08 , B21J5/12
Abstract: A suturing needle, comprising needle tip portion (1) having needle tip (1a), tapered portion (2) continuing to needle tip portion (1), trunk portion (3) continuing to tapered portion (2), and thread attaching portion (4) continuing to trunk portion (3); needle tip portion (1) has circular section continuing to sharp needle tip (1a), angular section continuing to sharp needle tip (1a), circular section continuing to blunt needle tip (1a) or angular section continuing to blunt needle tip (1a): wherein trunk portion (3) has the relations R1≧R2≧R3, when peak (5) or joint portion between the two flat faces has diameter R1, crest of ridges has a roundness of R2, and a valley (7) has roundness R3; and valley (7) is formed to correspond partially to peak (5), and the thickness becomes continuously larger from tapered portion (2) to trunk portion (3).
Abstract translation: 一种缝合针，包括具有针尖（1a）的针尖部分（1），连续到针尖部分（1）的锥形部分（2），连续到锥形部分（2）的躯干部分（3）和螺纹附接部分 4）继续到主干部分（3）; 针尖部分（1）具有连续到锋利的针尖（1a）的圆形部分，连续尖锐的针尖（1a）的角部分，连续钝针针尖（1a）的圆形部分或连续钝头针尖（1a）的角部， ：其中主干部分（3）具有关系R1> = R2> = R3，当两个平面之间的峰值（5）或接合部分具有直径R1时，脊的峰值具有R2的圆度和谷（7） 具有圆度R3; 并且谷部（7）形成为与峰（5）部分对应，并且厚度从锥形部分（2）连续变大到主体部分（3）。
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公开(公告)号：US20130220713A1
公开(公告)日：2013-08-29
申请号：US13391882
申请日：2010-10-26
Applicant: Masayuki Watanabe
Inventor： Masayuki Watanabe
IPC: B60L11/18
CPC classification number: B60L11/1874 , B60K1/04 , B60K2001/005 , B60K2001/0433 , H01M10/613 , H01M10/6561 , Y02E60/12
Abstract: A vehicle has an electric storage unit having a plurality of electric storage elements and outputting energy for use in running of the vehicle, a blower placed closer to the exterior of a vehicle body relative to the electric storage unit and supplying the electric storage unit with air for adjusting the temperature of the electric storage element, and a pedestal supporting the blower. The pedestal has a bend portion allowing movement of the blower to a position off the electric storage unit through deformation in response to an external force.
Abstract translation: 车辆具有多个蓄电元件并输出用于车辆行驶的能量的蓄电单元，相对于蓄电单元更靠近车体外部设置的鼓风机，并向蓄电单元供给空气 用于调节蓄电元件的温度和支撑鼓风机的基座。 基座具有弯曲部分，其允许鼓风机响应于外力而通过变形而移动到离开蓄电单元的位置。
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5.发明授权Sheet transportation device including electromagnetic component and control method thereof 有权包括电磁元件的片材输送装置及其控制方法
公开(公告)号：US08292294B2
公开(公告)日：2012-10-23
申请号：US13019499
申请日：2011-02-02
Applicant: Junichi Masuda , Masayuki Watanabe , Takeshi Ishida , Takahiro Tsujimoto , Takahiro Yokoya
Inventor： Junichi Masuda , Masayuki Watanabe , Takeshi Ishida , Takahiro Tsujimoto , Takahiro Yokoya
CPC classification number: B65H3/0669 , B65H2403/724 , B65H2553/412 , B65H2801/06
Abstract: A sheet transportation device includes a transportation path for transportation of a sheet, a transportation unit for applying force to a sheet on the transportation path, and an electromagnetic component for driving the transportation unit by receiving supply of electric power. At the sheet transportation device, the absence/presence of a sheet is detected at a downstream side of the region where the transportation unit applies force to a sheet in the transportation path, and counter electromotive force induced in response to electric power being supplied to the electromagnetic component is supplied as the electric power for the detector.
Abstract translation: 片材输送装置包括用于输送片材的输送路径，用于向输送路径上的片材施加力的输送单元和用于通过接收电力来驱动输送单元的电磁部件。 在片材输送装置中，在输送单元向输送路径中的纸张施加力的区域的下游侧检测纸张的不存在，并且响应于向第 提供电磁成分作为检测器的电力。
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公开(公告)号：US20110239519A1
公开(公告)日：2011-10-06
申请号：US13064482
申请日：2011-03-28
Applicant: Masaru Akiba , Masayuki Watanabe , Hideyuki Naitou , Eiji Sugaya
Inventor： Masaru Akiba , Masayuki Watanabe , Hideyuki Naitou , Eiji Sugaya
CPC classification number: A01K87/04
Abstract: A fishing line guide includes a frame made of a fiber reinforced resin. The fiber reinforced resin includes a reinforced fiber extending in an extending direction of part forming the frame.
Abstract translation: 钓鱼线引导件包括由纤维增强树脂制成的框架。 纤维增强树脂包括沿着形成框架的部分的延伸方向延伸的增强纤维。
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公开(公告)号：USD643904S1
公开(公告)日：2011-08-23
申请号：US29381760
申请日：2010-12-22
Applicant: Masaru Akiba , Masayuki Watanabe
Designer： Masaru Akiba , Masayuki Watanabe
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公开(公告)号：US08004434B2
公开(公告)日：2011-08-23
申请号：US12684048
申请日：2010-01-07
Applicant: Kenichi Nakazato , Masayuki Watanabe
Inventor： Kenichi Nakazato , Masayuki Watanabe
IPC: H03M1/48
CPC classification number: H03M1/1038 , H03M1/485
Abstract: An RD converter is disclosed that has a first multiplier multiplying a resolver signal S1 by an output of a SIN ROM; a second multiplier multiplying a resolver signal S2 by an output of a COS ROM; a subtractor subtracting an output of the first multiplier from an output of the second multiplier; a synchronous detecting circuit detecting synchronously an output of the subtractor with reference to an excitation signal; a controller controlling an output angle θ′ to make an output of the synchronous detecting circuit equal to zero; a correction data part outputting a correction angle θc for the output angle θ′; an adder adding the output angle θ′ and the correction angle θc; the SIN ROM producing a sine value of a result from the adder; and the COS ROM producing a cosine value of the result.
Abstract translation: 公开了一种RD转换器，其具有将解算器信号S1乘以SIN ROM的输出的第一乘法器; 将解算器信号S2乘以COS ROM的输出的第二乘法器; 减法器，从所述第二乘法器的输出中减去所述第一乘法器的输出; 同步检测电路，参照激励信号同步检测减法器的输出; 控制输出角度的控制器;'使同步检测电路的输出等于零; 校正数据部分输出校正角度和输出角度的角度; 一个加法器，加上输出角度＆thetas;'和校正角度＆amp; c; 该SIN ROM产生来自加法器的结果的正弦值; 和COS ROM产生结果的余弦值。
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公开(公告)号：US07966101B2
公开(公告)日：2011-06-21
申请号：US11570109
申请日：2006-01-20
Applicant: Yasunori Mitani , Masayuki Watanabe
Inventor： Yasunori Mitani , Masayuki Watanabe
Abstract: The phase and time information of a voltage at a power supply outlet is detected at points, and sent to a data server. With one end of a system used as a phase angle reference, the data server observes phase differences at another end, and at a center. The data server then extracts an inter-system fluctuation component from an obtained fluctuation, and constructs an expanded combined vibration model for data sets obtained through first- and second-order differentiations of the component. The expanded combined vibration model is obtained by expanding a combined vibration model to include a known model of a PSS provided for a generator of interest. Time-series data regarding state variables of the PSS at the time of construction of the expanded combined vibration model are obtained, and PSS parameters are determined directly therefrom by the expanded combined vibration model, thereby achieving stabilization of dominant modes.
Abstract translation: 在点处检测电源插座上的电压的相位和时间信息，并发送到数据服务器。 将系统的一端用作相位角参考，数据服务器在另一端和中心观察相位差。 然后，数据服务器从获得的波动中提取系统间波动分量，并为通过该组件的一阶和二阶微分获得的数据集构建扩展的组合振动模型。 扩展的组合振动模型通过扩展组合振动模型来获得，以包括为感兴趣的发生器提供的PSS的已知模型。 获得关于在扩展的组合振动模型构建时的PSS的状态变量的时间序列数据，通过扩展的组合振动模型直接确定PSS参数，从而实现主要模式的稳定。
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公开(公告)号：US20100263257A1
公开(公告)日：2010-10-21
申请号：US12662039
申请日：2010-03-29
Applicant: Masaru Akiba , Eiji Sugaya , Hideyuki Naitou , Atushi Saitou , Hiroyuki Mori , Tomoyoshi Turufuji , Masayuki Watanabe
Inventor： Masaru Akiba , Eiji Sugaya , Hideyuki Naitou , Atushi Saitou , Hiroyuki Mori , Tomoyoshi Turufuji , Masayuki Watanabe
CPC classification number: A01K87/04
Abstract: A fishline guide according to the present invention has a frame which includes a fixing portion which is mounted on a fishing rod, a ring holding portion, to which a guide ring through which a fishline passes is attached, and a support leg portion which connects the ring holding portion and the fixing portion. The frame is composed of a plurality of fiber-reinforced resin layers in which fiber-reinforced prepregs in which reinforcing fibers are impregnated with synthetic resin are laminated.
Abstract translation: 根据本发明的钓线导轨具有框架，该框架包括安装在钓鱼杆上的固定部分，安装有钓线穿过的导向环的环保持部分和连接着钓线的支撑腿部分 环保持部和固定部。 框架由多个纤维增强树脂层组成，其中层合有用合成树脂浸渍增强纤维的纤维增强预浸料。
