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公开(公告)号：US12041989B2
公开(公告)日：2024-07-23
申请号：US17220648
申请日：2021-04-01
CPC分类号： A41D13/1192 , B01D46/0028 , B01D2239/025 , B01D2239/0258
摘要： A reusable face mask for covering the mouth and nose of a wearer to prevent the passage of pathogenic biological airborne particulates. The mask has three layers including a filter material made of graphene and infused with activated copper carbon. A Bluetooth transmitter wirelessly transmits a continuous frequency of 2.4 GHz to destroy and prevent the passage of any human pathogens from entering, while freely allowing the passage of air in both directions.
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公开(公告)号：US08349865B2
公开(公告)日：2013-01-08
申请号：US12677375
申请日：2008-09-08
申请人： Tony Siu , Jonathan Young , Michael Altman , Alan Northrup , Matthew Katcher , Ellalahewage Sathyajith Kumarasinghe , Ekaterina Kozina , Scott Peterson , Matthew Childers
发明人： Tony Siu , Jonathan Young , Michael Altman , Alan Northrup , Matthew Katcher , Ellalahewage Sathyajith Kumarasinghe , Ekaterina Kozina , Scott Peterson , Matthew Childers
IPC分类号： C07D471/06 , A61K31/4375
CPC分类号： C07D471/04 , C07D471/14
摘要： The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.
摘要翻译： 本发明提供抑制四种已知的哺乳动物JAK激酶（JAK1，JAK2，JAK3和TYK2）和PDK1的化合物。 本发明还提供了包含这种抑制化合物的组合物和通过向需要治疗骨髓增生性疾病或癌症的患者施用化合物来抑制JAK1，JAK2，JAK3 TYK2和PDK1的活性的方法。
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公开(公告)号：US20210307430A1
公开(公告)日：2021-10-07
申请号：US17220648
申请日：2021-04-01
摘要： A reusable face mask for covering the mouth and nose of a wearer to prevent the passage of pathogenic biological airborne particulates. The mask has three layers including a filter material made of graphene and infused with activated copper carbon. A Bluetooth transmitter wirelessly transmits a continuous frequency of 2.4 GHz to destroy and prevent the passage of any human pathogens from entering, while freely allowing the passage of air in both directions.
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公开(公告)号：US20100197634A1
公开(公告)日：2010-08-05
申请号：US12677375
申请日：2008-09-08
申请人： Tony Siu , Jonathan Young , Michael Altman , Alan Northrup , Matthew Katcher , Ellalahewage Sathyajith Kumarasinghe , Ekaterina Kozina , Scott Peterson , Matthew Childers
发明人： Tony Siu , Jonathan Young , Michael Altman , Alan Northrup , Matthew Katcher , Ellalahewage Sathyajith Kumarasinghe , Ekaterina Kozina , Scott Peterson , Matthew Childers
IPC分类号： A61K31/69 , C07D471/02 , A61K31/4375 , C07D413/14 , A61K31/5377 , C07F5/02 , C07D401/14 , A61K31/506 , C07D471/12 , A61K31/496 , A61P35/00
CPC分类号： C07D471/04 , C07D471/14
摘要： The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.
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公开(公告)号：US6036911A
公开(公告)日：2000-03-14
申请号：US14367
申请日：1998-01-27
申请人： Joseph W. Allison , Jan Richter , Craig Matthew Childers , Dennis R. Smalley , Charles W. Hull , Paul F. Jacobs
发明人： Joseph W. Allison , Jan Richter , Craig Matthew Childers , Dennis R. Smalley , Charles W. Hull , Paul F. Jacobs
CPC分类号： G06T17/20 , B29C67/0092 , G01J1/4257 , G03F7/70416 , G06T15/503 , G06T17/10 , G05B2219/49013
摘要： An improved method for stereolithographically making an object by alternating the order in which similar sets of vectors are exposed over two or more layers. In another method, a pattern of tightly packed hexagonal tiles are drawn. Each tile is isolated from its neighboring tiles by specifying breaks of unexposed material between the tiles. Using an interrupted scan method, vectors are drawn with periodic breaks along their lengths. In another method, modulator and scanning techniques are used to reduce exposure problems associated with the acceleration and deceleration of the scanning system when jumping between vectors or changing scanning directions.
摘要翻译： 通过交替在两个或多个层上暴露相似的矢量集合的顺序来立体定向制作物体的改进方法。 在另一种方法中，绘制紧密包装的六边形瓦片的图案。 通过指定瓷砖之间未曝光材料的断裂，每个瓷砖与其相邻的瓷砖隔离。 使用中断的扫描方法，沿其长度绘制周期性断点的向量。 在另一种方法中，调制器和扫描技术用于在向量之间跳跃或改变扫描方向时减少与扫描系统的加速和减速有关的暴露问题。
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