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17 条记录 (耗时 0.024 秒)

    Expansion joint cover assemblies
    2.
    发明授权
    Expansion joint cover assemblies 失效
    膨胀接头盖组件

    公开(公告)号：US5060439A

    公开(公告)日：1991-10-29

    申请号：US540071

    申请日：1990-06-19

    申请人： Matthew J. Clements ,  Maxim A. Fedor ,  Jerry T. Moffitt ,  Lisa Ye ,  John F. Wadsworth

    发明人： Matthew J. Clements ,  Maxim A. Fedor ,  Jerry T. Moffitt ,  Lisa Ye ,  John F. Wadsworth

    IPC分类号： E04B1/68

    CPC分类号： E04B1/6815

    摘要： Expansion joint cover assemblies are disclosed which are structured and dimensioned for use in covering expansion joints or spaces between adjacent structural sections of a building such as spaced floors or floor and wall sections. The assemblies include base members adapted to be positioned and secured to the adjacent structural sections and a leaf spring cover member fixedly interconnected to one of the base members at one end and bridging the expansion joint or space between the structural sections in a cantilever manner such that the cover member lies in a plane essentially flush with the floor section or sections and is structured and dimensioned to be slidably interconnected with the other base member to provide a secure, functionally effective and aesthetically pleasing assembly for accommodating translational relative movement of the structural sections.

    摘要翻译： 公开了膨胀接头盖组件，其结构和尺寸用于覆盖建筑物的相邻结构部分之间的膨胀接缝或空间，例如间隔开的地板或地板和壁部分。 组件包括适于定位并固定到相邻结构部分的基部构件和在一端固定地互连到一个基部构件的板簧盖构件，并以悬臂方式桥接结构部分之间的膨胀接头或空间，使得 盖构件位于基本上与地板部分齐平的平面中，并且其结构和尺寸被设计成与另一个基部构件滑动互连，以提供用于容纳结构部分的平移相对运动的安全的，功能有效的和美学上令人满意的组件。

    Product dispenser for variable stacked articles
    7.
    发明授权
    Product dispenser for variable stacked articles 失效
    用于可变堆放物品的产品分配器

    公开(公告)号：US06662968B2

    公开(公告)日：2003-12-16

    申请号：US10131738

    申请日：2002-04-24

    申请人： Matthew J. Clements

    发明人： Matthew J. Clements

    IPC分类号： B65H3120

    CPC分类号： G07F11/24 ,  G07F11/04

    摘要： A product dispenser of the type adapted to release articles from vertical stacks is disclosed, which is configured to dispense a variety of articles whether in bulk or singularly. The present vending apparatus provides a main housing that is configured to receive interchangeable release mechanisms, with each mechanism dependent upon whether the dispensed article(s) is generally flat or of the small round type distributed by bulk similar to candies. The bottom surface of the product compartment defined on the top of main housing is configured to allow variability in the type of products released from the vertically mounted product cartridge.

    摘要翻译： 公开了一种适于从垂直堆叠中释放物品的产品分配器，其被配置为分配多种物品，无论是批量还是单独的。 本发明的自动售货装置提供一个主壳体，该主壳体构造成接收可互换的释放机构，每个机构取决于分配的物品是大致平坦的，还是散装类似于糖果的小型圆形。 限定在主壳体顶部的产品隔室的底部表面被配置为允许从垂直安装的产品盒释放的产品类型的变化。

    Substituted furo[2,3-B] pyridine derivatives as cannabinoid-1 receptor modulators
    10.
    发明申请
    Substituted furo[2,3-B] pyridine derivatives as cannabinoid-1 receptor modulators 审中-公开
    取代的呋喃并[2,3-B]吡啶衍生物作为大麻素-1受体调节剂

    公开(公告)号：US20080269279A1

    公开(公告)日：2008-10-30

    申请号：US12082013

    申请日：2008-04-07

    申请人： Matthew J. Clements ,  John S. Debenham ,  Jeffrey J. Hale ,  Christina B. Madsen-Duggan ,  Thomas F. Walsh ,  Andrey V. Peresypkin ,  Roy Helmy

    发明人： Matthew J. Clements ,  John S. Debenham ,  Jeffrey J. Hale ,  Christina B. Madsen-Duggan ,  Thomas F. Walsh ,  Andrey V. Peresypkin ,  Roy Helmy

    IPC分类号： A61K31/4355 ,  C07D471/04 ,  A61P25/00 ,  A61P3/04

    CPC分类号： C07D491/048

    摘要： Novel compounds of the structural formula (I) are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, Alzheimer's disease, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia. The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, cirrhosis of the liver, non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and the promotion of wakefulness.

    摘要翻译： 结构式（I）的新型化合物是大麻素-1（CB1）受体的拮抗剂和/或反向激动剂，可用于治疗，预防和抑制由CB1受体介导的疾病。 本发明的化合物可用作治疗精神病，记忆缺陷，认知障碍，阿尔茨海默病，偏头痛，神经病，包括多发性硬化症和神经 - 巴利综合征的神经炎症性疾病以及病毒性脑炎的炎症性后遗症的中枢作用药物 脑血管意外，头部创伤，焦虑障碍，压力，癫痫，帕金森病，运动障碍和精神分裂症。 这些化合物还可用于治疗药物滥用障碍，治疗肥胖或进食障碍，以及治疗哮喘，便秘，慢性肠假性梗阻，肝硬化，非酒精性脂肪性肝病（NAFLD ），非酒精性脂肪性肝炎（NASH），以及促进觉醒。