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    Implantable multi-electrode device
    3.
    发明授权
    Implantable multi-electrode device 有权
    可植入多电极装置

    公开(公告)号：US08798737B2

    公开(公告)日：2014-08-05

    申请号：US12442133

    申请日：2007-09-18

    Applicant: Matthias Merz ,  Youri V. Ponomarev ,  Remco H. W. Pijnenburg

    Inventor： Matthias Merz ,  Youri V. Ponomarev ,  Remco H. W. Pijnenburg

    IPC: A61N1/00

    CPC classification number: A61N1/0529 ,  A61B5/04001 ,  A61L31/148 ,  A61N1/0531 ,  A61N1/0534 ,  A61N1/0536 ,  A61N1/0539 ,  A61N1/0558 ,  A61N1/36082

    Abstract: The invention provides an implantable multi-electrode device (300) and related methods and apparatuses. In one embodiment, the invention includes an implantable device (300) comprising: an assembly block (320); and a plurality of leads (340 . . . 348) radiating from the assembly block (320), each of the plurality of leads (340 . . . 348) containing at least one electrode (342A), such that the electrodes are distributed within a three-dimensional space, wherein the assembly block (320) includes a barb (350) for anchoring the assembly block (320) within implanted tissue.

    Abstract translation: 本发明提供一种可植入式多电极装置（300）及其相关方法和装置。 在一个实施例中，本发明包括可植入装置（300），包括：组装块（320）; 以及从所述组装块（320）辐射的多个引线（340 ... 348），所述多个引线（340 ... 348）中的每一个包含至少一个电极（342A），使得所述电极分布在 三维空间，其中组装块（320）包括用于将组装块（320）固定在植入的组织内的倒钩（350）。

    PH SENSOR AND MANUFACTURING METHOD
    4.
    发明申请
    PH SENSOR AND MANUFACTURING METHOD 有权
    PH传感器和制造方法

    公开(公告)号：US20130069120A1

    公开(公告)日：2013-03-21

    申请号：US13600385

    申请日：2012-08-31

    Applicant: Matthias MERZ ,  Coenraad Cornelis TAK ,  Romano HOOFMAN

    Inventor： Matthias MERZ ,  Coenraad Cornelis TAK ,  Romano HOOFMAN

    IPC: G01N27/414 ,  H01L21/98

    CPC classification number: G01N27/302 ,  G01N27/4148 ,  G01N27/4167 ,  G01N33/02 ,  G01N33/04 ,  G01N33/12 ,  H01L2224/48091 ,  H01L2924/1815 ,  Y10T29/49002 ,  H01L2924/00014

    Abstract: Disclosed is a pH sensor comprising a carrier (10) comprising a plurality of conductive tracks and an exposed conductive area (40) defining a reference electrode connected to one of said conductive tracks; a sensing device (30) mounted on the carrier and connected at least one other of said conductive tracks; an encapsulation (20) covering the carrier, said encapsulation comprising a first cavity (22) exposing a surface (32) of the sensing device and a second cavity (24) exposing the exposed conductive area, said second cavity comprising a reference electrode material (42) and an ion reservoir material (44) sharing at least one ion type with said reference electrode material, the reference electrode material being sandwiched between the exposed conductive area and the ion reservoir material. A method of manufacturing such a pH sensor is also disclosed.

    Abstract translation: 公开了一种pH传感器，其包括包括多个导电轨道的载体（10）和限定连接到所述导电轨道之一的参考电极的暴露导电区域（40） 感测装置（30），其安装在所述载体上并且连接至少另一个所述导电轨道; 覆盖所述载体的封装（20），所述封装包括暴露所述感测装置的表面（32）的第一空腔（22）和暴露所述暴露的导电区域的第二空腔（24），所述第二空腔包括参考电极材料 42）和与所述参考电极材料共享至少一种离子型离子储存器材料（44），所述参考电极材料夹在所述暴露的导电区域和所述离子储存器材料之间。 还公开了制造这种pH传感器的方法。

    SENSOR
    5.
    发明申请
    SENSOR 有权
    传感器

    公开(公告)号：US20120260732A1

    公开(公告)日：2012-10-18

    申请号：US13382726

    申请日：2010-07-16

    Applicant: Aurelie Humbert ,  Youri Victorovitch Ponomarev ,  Roel Daamen ,  Matthias Merz

    Inventor： Aurelie Humbert ,  Youri Victorovitch Ponomarev ,  Roel Daamen ,  Matthias Merz

    IPC: G01N27/12 ,  H01B13/00 ,  B05D5/12

    CPC classification number: G01N27/223 ,  G01N33/004

    Abstract: A sensor (2) for sensing a first substance and a second substance, the sensor comprising first (3) and second (5) sensor components each comprising a first material (20), the first material being sensitive to both the first substance and the second substance, the sensor further comprising a barrier (18) for preventing the second substance from passing into the second sensor component (5).

    Abstract translation: 一种用于感测第一物质和第二物质的传感器（2），所述传感器包括第一（3）和第二（5）个传感器部件，每个传感器部件包括第一材料（20），所述第一材料对第一物质和 第二物质，传感器还包括用于防止第二物质进入第二传感器部件（5）的阻挡层（18）。

    ELECTROCHEMICAL POTENTIOMETRIC SENSING WITHOUT REFERENCE ELECTRODE
    7.
    发明申请
    ELECTROCHEMICAL POTENTIOMETRIC SENSING WITHOUT REFERENCE ELECTRODE 有权
    无参考电极的电化学电位感测

    公开(公告)号：US20110208457A1

    公开(公告)日：2011-08-25

    申请号：US13061110

    申请日：2009-08-24

    Applicant: Matthias Merz ,  Youri Victorovitch Ponomarev ,  Gilberto Curatola

    Inventor： Matthias Merz ,  Youri Victorovitch Ponomarev ,  Gilberto Curatola

    IPC: G06F19/00

    CPC classification number: G01N27/4148 ,  G01N27/4145

    Abstract: The invention relates to a method of determining a charged particle concentration in an analyte (100), the method comprising steps of: i) determining at least two measurement points of a surface-potential versus interface-temperature curve (c1, c2, c3, c4), wherein the interface temperature is obtained from a temperature difference between a first interface between a first ion-sensitive dielectric (Fsd) and the analyte (100) and a second interface between a second ion-sensitive dielectric (Ssd) and the analyte (100), and wherein the surface-potential is obtained from a potential difference between a first electrode (Fe) and a second electrode (Se) onto which said first ion-sensitive dielectric (Fsd) and said second ion-sensitive dielectric (Ssd) are respectively provided, And ii) calculating the charged particle concentration from locations of the at least two measurement points of said curve (c1, c2, c3, c4). This method, which still is a potentiometric electrochemical measurement, exploits the temperature dependency of a surface-potential of an ion-sensitive dielectric in an analyte. The invention further provides an electrochemical sensor deny for determining a charged particle concentration in an analyte. The invention also provides various sensors which can be used to determine the charged particle concentration, i.e. EGFET's and EIS capacitors.

    Abstract translation: 本发明涉及一种测定分析物（100）中带电粒子浓度的方法，所述方法包括以下步骤：i）确定表面电位对界面温度曲线（c1，c2，c3，c3）的至少两个测量点， c4），其中所述界面温度是由第一离子敏感电介质（Fsd）和分析物（100）之间的第一界面与第二离子敏感电介质（Ssd）与分析物之间的第二界面 （100），并且其中所述表面电位由所述第一离子敏感电介质（Fsd）和所述第二离子敏感电介质（Ssd）上的第一电极（Fe）和第二电极（Se）之间的电位差获得， ），和ii）从所述曲线（c1，c2，c3，c4）的至少两个测量点的位置计算带电粒子浓度。 这种仍然是电位电化学测量的方法利用分析物中离子敏感电介质的表面电位的温度依赖性。 本发明还提供了一种用于确定分析物中带电粒子浓度的电化学传感器。 本发明还提供可用于确定带电粒子浓度的各种传感器，即EGFET和EIS电容器。

    SENSOR
    8.
    发明申请
    SENSOR 有权
    传感器

    公开(公告)号：US20110079649A1

    公开(公告)日：2011-04-07

    申请号：US12889832

    申请日：2010-09-24

    Applicant: Roel DAAMEN ,  Aurelie HUMBERT ,  Matthias MERZ ,  Youri Victorovitch PONOMAREV

    Inventor： Roel DAAMEN ,  Aurelie HUMBERT ,  Matthias MERZ ,  Youri Victorovitch PONOMAREV

    IPC: G06K19/077 ,  H01L23/48

    CPC classification number: G01D5/14 ,  H01L2224/11

    Abstract: A sensor comprising a silicon substrate having a first and a second surface, integrated circuitry provided on the first surface of the silicon substrate, and a sensor structure provided on the second surface of the silicon substrate. The sensor structure and the integrated circuitry are electrically coupled to each other.

    Abstract translation: 一种传感器，包括具有第一和第二表面的硅衬底，设置在硅衬底的第一表面上的集成电路以及设置在硅衬底的第二表面上的传感器结构。 传感器结构和集成电路彼此电耦合。

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