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1.发明授权Topical compositions comprising inorganic particulates and an alkoxylated diphenylacrylate compound 有权包含无机颗粒和烷氧基化二苯基丙烯酸酯化合物的局部组合物公开(公告)号：US08765156B2
公开(公告)日：2014-07-01
申请号：US12771237
申请日：2010-04-30
IPC分类号： A61K8/02 , A61K8/00 , A61Q17/04 , A61K33/24 , A61K9/50 , A61K8/27 , A61K47/32 , A61K47/24 , A61K8/40 , A61K31/12 , A61K33/30 , A61K8/29 , A61K9/00 , A61K47/10 , A61K47/06
CPC分类号： A61K31/12 , A61K8/27 , A61K8/29 , A61K8/40 , A61K9/0014 , A61K9/5026 , A61K33/24 , A61K33/30 , A61K47/06 , A61K47/10 , A61K47/24 , A61K47/32 , A61Q17/04 , A61K2300/00
摘要： A topical composition of improved spreadability and aesthetical appeal is provided, which contains inorganic particulates in combination with an alkoxylated diphenylacrylate compound. Preferably, the topical composition is a sunscreen composition that contains inorganic or physical sunscreen agents in combination with an alkoxylated α-cyanodiphenylacrylate compound, which is characterized by improved photo-protection of the skin and is effective in preventing/reducing photo-damage of the skin upon exposure to sunlight or other sources of light in the ultraviolet (UV), visible, and infrared (IR) ranges.
摘要翻译： 提供了具有改善的铺展性和美学吸引力的局部组合物，其包含与烷氧基化二苯基丙烯酸酯化合物组合的无机颗粒。 优选地，局部组合物是防晒组合物，其包含与烷氧基化α-氰基二苯基丙烯酸酯化合物组合的无机或物理防晒剂，其特征在于改善皮肤的光保护并且有效地预防/减少皮肤的光损伤 在紫外线（UV），可见光和红外（IR）范围内暴露于阳光或其他光源时。
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2.发明申请Cosmetic Compositions Comprising Cyanodiphenylacrylates And Film Forming Polmers 审中-公开包含氰基二苯基丙烯酸酯和成膜剂的化妆品组合物公开(公告)号：US20120189665A1
公开(公告)日：2012-07-26
申请号：US13266598
申请日：2010-04-28
摘要： A composition comprising at least one α-cyanodiphenylacrylate and at least one organosiloxane-based film forming polymer.
摘要翻译： 包含至少一种α-氰基二苯基丙烯酸酯和至少一种基于有机硅氧烷的成膜聚合物的组合物。
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公开(公告)号：US09095543B2
公开(公告)日：2015-08-04
申请号：US13266578
申请日：2010-04-28
IPC分类号： A61K31/12 , A61K8/40 , A61K8/893 , A61K8/894 , A61Q19/00 , A61Q1/02 , A61Q1/06 , A61Q1/10 , A61Q17/04
CPC分类号： A61K8/40 , A61K8/062 , A61K8/064 , A61K8/27 , A61K8/29 , A61K8/66 , A61K8/891 , A61K8/893 , A61K8/894 , A61K8/99 , A61K31/12 , A61K2800/52 , A61K2800/85 , A61Q1/02 , A61Q1/06 , A61Q1/10 , A61Q17/04 , A61Q19/00 , A61Q19/001
摘要： A topical composition comprising at least one α-cyanodiphenylacrylate and dimethicone silylate.
摘要翻译： 包含至少一种α-氰基二苯基丙烯酸酯和聚二甲基硅氧烷甲硅烷基酯的局部组合物。
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4.发明申请Topical Compositions Comprising Inorganic Particulates And An Alkoxylated Diphenylacrylate Compound 有权包含无机颗粒和烷氧基化二苯基丙烯酸酯化合物的局部组合物公开(公告)号：US20110110988A1
公开(公告)日：2011-05-12
申请号：US12771237
申请日：2010-04-30
CPC分类号： A61K31/12 , A61K8/27 , A61K8/29 , A61K8/40 , A61K9/0014 , A61K9/5026 , A61K33/24 , A61K33/30 , A61K47/06 , A61K47/10 , A61K47/24 , A61K47/32 , A61Q17/04 , A61K2300/00
摘要： A topical composition of improved spreadability and aesthetical appeal is provided, which contains inorganic particulates in combination with an alkoxylated diphenylacrylate compound. Preferably, the topical composition is a sunscreen composition that contains inorganic or physical sunscreen agents in combination with an alkoxylated α-cyanodiphenylacrylate compound, which is characterized by improved photo-protection of the skin and is effective in preventing/reducing photo-damage of the skin upon exposure to sunlight or other sources of light in the ultraviolet (UV), visible, and infrared (IR) ranges.
摘要翻译： 提供了具有改善的铺展性和美学吸引力的局部组合物，其包含与烷氧基化二苯基丙烯酸酯化合物组合的无机颗粒。 优选地，局部组合物是防晒组合物，其包含与烷氧基化α-氰基二苯基丙烯酸酯化合物组合的无机或物理防晒剂，其特征在于改善皮肤的光保护并且有效地预防/减少皮肤的光损伤 在紫外线（UV），可见光和红外（IR）范围内暴露于阳光或其他光源时。
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5.发明申请Topical Compositions Comprising An Alkoxylated Diphenylacrylate Compound And An Organic Nonionic Emulsifier 审中-公开包含烷氧基化二苯基丙烯酸酯化合物和有机非离子乳化剂的局部组合物公开(公告)号：US20120201766A1
公开(公告)日：2012-08-09
申请号：US13266620
申请日：2010-04-28
CPC分类号： A61K31/277 , A61K8/39 , A61K8/40 , A61K8/86 , A61K9/0014 , A61K47/10 , A61Q17/04
摘要： A topical composition of improved spreadability and aesthetical appeal is provided, which contains a stable emulsion base formed by combining an alkoxylated diphenylacrylate compound and a nonionic organic emulsifier with a pharmaceutically or cosmetically acceptable carrier. Preferably, the topical composition is a sunscreen composition that further contains inorganic or physical sunscreen agents dispersed in such a stable emulsion base, which is characterized by improved photo-protection of the skin and is effective in preventing/reducing photo-damage of the skin upon exposure to sunlight or other sources of light in the ultraviolet (UV), visible, and infrared (IR) ranges.
摘要翻译： 提供了具有改进的铺展性和美学吸引力的局部组合物，其包含通过将烷氧基化二苯基丙烯酸酯化合物和非离子有机乳化剂与药学或化学上可接受的载体组合而形成的稳定的乳液基质。 优选地，局部组合物是防晒组合物，其进一步包含分散在这种稳定的乳液基质中的无机或物理防晒剂，其特征在于改善皮肤的光保护，并且有效地防止/减少皮肤的光损伤 暴露于紫外线（UV），可见光和红外（IR）范围内的阳光或其他光源。
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6.发明申请Topical Compositions Comprising An Alkoxylated Diphenylacrylate Compound And An Aryl Carboxylic Ester 审中-公开包含烷氧基化二苯基丙烯酸酯化合物和芳基羧酸酯的局部组合物公开(公告)号：US20120134943A1
公开(公告)日：2012-05-31
申请号：US13266439
申请日：2010-04-28
CPC分类号： A61K31/12 , A61K8/35 , A61K8/37 , A61K8/40 , A61K33/24 , A61K33/30 , A61K45/06 , A61Q17/04 , A61K2300/00
摘要： A topical composition containing an alkoxylated diphenylacrylate compound and an aryl carboxylic ester is provided. Preferably, the topical composition is a sunscreen composition containing α-ethylhexyl α-cyano-β-(4-methoxyphenyl)-β-phenylacrylate and 2-phenylethyl benzoate, and optionally further containing 4,4′-t-butyl methoxydibenzoylmethane, which is characterized by improved photo-protection of the skin and is effective in preventing/reducing photo-damage of the skin upon exposure to sunlight or other sources of light in the ultraviolet (UV), visible, and infrared (IR) ranges.
摘要翻译： 提供含有烷氧基化二苯基丙烯酸酯化合物和芳基羧酸酯的局部组合物。 优选地，局部组合物是含有α-氰基 - （4-甲氧基苯基） - 苯基丙烯酸α-苯乙酯和苯乙酸2-苯基乙酯的α-乙基己基酯和任选地进一步含有4,4'-叔丁基甲氧基二苯甲酰甲烷的防晒组合物， 其特征在于改善皮肤的光保护，并且在紫外线（UV），可见光和红外（IR））范围内暴露于阳光或其他光源时有效防止/减少皮肤的光损伤。
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公开(公告)号：US20070187327A1
公开(公告)日：2007-08-16
申请号：US11673119
申请日：2007-02-09
申请人： Liliana Sophie George , George Cioca , Ionita-Manzatu Vasile , Kretzschmar-Dovi Kathleen Mary , Mirela Cristina Ionita-Manzatu
发明人： Liliana Sophie George , George Cioca , Ionita-Manzatu Vasile , Kretzschmar-Dovi Kathleen Mary , Mirela Cristina Ionita-Manzatu
IPC分类号： B01D61/00
摘要： The present invention relates to enhanced structured water containing mineral ions that are released by water-insoluble minerals and integrated into water clusters in the structured water. Specifically, the present invention provides compositions containing structured water selected from the group consisting of I water, S water, and a combination thereof. The structured water includes at least one charged cluster of water molecules having at least one mineral ion bound therewith to form a cluster complex. The mineral ions in the cluster complex exhibit enhanced biological activities, in comparison with mineral ions in un-structured waters. Further, by incorporating at least one bridging agent, and at least one capping agent into the cluster complex, the compositions of the present invention exhibit bright and intense colors with surprising and unexpected color stability.
摘要翻译： 本发明涉及含有矿物离子的增强的结构化水，其由水不溶性矿物质释放并结合在结构化水中的水簇中。 具体地说，本发明提供含有选自I水，S水及其组合的结构水的组合物。 结构化水包括至少一个具有至少一个与之结合的矿物离子的带电簇的水分子，以形成簇复合物。 与非结构化水体中的矿物离子相比，簇状复合物中的矿物离子显示出增强的生物活性。 此外，本发明的组合物通过将至少一种桥连剂和至少一种封端剂掺入到簇络合物中，呈现明亮且强烈的颜色，具有出人意料的和意想不到的颜色稳定性。
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公开(公告)号：US6139855A
公开(公告)日：2000-10-31
申请号：US243362
申请日：1999-02-01
申请人： Gheorghe Cioca , Joseph Gubernick , Andrew J. Bevacqua , Nicolae Vrabie , Daniel H. Maes , Kenneth D. Marenus , Edward Pelle , Neelam Muizzuddin , Vasile Ionita-Manzatu , Mirela Cristina Ionita-Manzatu
发明人： Gheorghe Cioca , Joseph Gubernick , Andrew J. Bevacqua , Nicolae Vrabie , Daniel H. Maes , Kenneth D. Marenus , Edward Pelle , Neelam Muizzuddin , Vasile Ionita-Manzatu , Mirela Cristina Ionita-Manzatu
IPC分类号： A61K8/19 , A61K8/00 , A61K8/02 , A61K8/06 , A61K8/46 , A61K33/00 , A61K45/00 , A61K47/02 , A61Q19/00 , C02F1/00 , C02F1/461 , A61K9/10
CPC分类号： C02F1/4618 , A61K33/00 , C02F1/005 , C02F2103/026 , Y10S514/937
摘要： The invention relates to composition having enhanced biological activity, the compositions comprising at least one structured water. In particular, the compositions contain a combination of I and S waters and a biologically active agent, in which the activity of the agent is increased relative to its activity in a non-structured water composition.
摘要翻译： 本发明涉及具有增强的生物活性的组合物，所述组合物包含至少一种结构化水。 特别地，组合物含有I和S水的组合和生物活性剂，其中药物的活性相对于其在非结构化水组合物中的活性而增加。
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9.发明申请Topical Compositions Comprising Inorganic Particulates And An Alkoxylated Diphenylacrylate Compound 审中-公开包含无机颗粒和烷氧基化二苯基丙烯酸酯化合物的局部组合物公开(公告)号：US20120121673A1
公开(公告)日：2012-05-17
申请号：US13359017
申请日：2012-01-26
CPC分类号： A61K31/12 , A61K8/27 , A61K8/29 , A61K8/40 , A61K9/0014 , A61K9/5026 , A61K33/24 , A61K33/30 , A61K47/06 , A61K47/10 , A61K47/24 , A61K47/32 , A61Q17/04 , A61K2300/00
摘要： A topical composition of improved spreadability and aesthetical appeal is provided, which contains inorganic particulates in combination with an alkoxylated diphenylacrylate compound. Preferably, the topical composition is a sunscreen composition that contains inorganic or physical sunscreen agents in combination with an alkoxylated α-cyanodiphenylacrylate compound, which is characterized by improved photo-protection of the skin and is effective in preventing/reducing photo-damage of the skin upon exposure to sunlight or other sources of light in the ultraviolet (UV), visible, and infrared (IR) ranges.
摘要翻译： 提供了具有改善的铺展性和美学吸引力的局部组合物，其包含与烷氧基化二苯基丙烯酸酯化合物组合的无机颗粒。 优选地，局部组合物是防晒组合物，其包含与烷氧基化α-氰基二苯基丙烯酸酯化合物组合的无机或物理防晒剂，其特征在于改善皮肤的光保护并且有效地预防/减少皮肤的光损伤 在紫外线（UV），可见光和红外（IR）范围内暴露于阳光或其他光源时。
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