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33 条记录 (耗时 0.016 秒)

    Electrical energy transfer assembly for a motorcycle wheel
    2.
    发明申请
    Electrical energy transfer assembly for a motorcycle wheel 审中-公开
    摩托车车轮的电能传递组件

    公开(公告)号：US20070058384A1

    公开(公告)日：2007-03-15

    申请号：US11224091

    申请日：2005-09-13

    申请人： Mohammed Khan

    发明人： Mohammed Khan

    IPC分类号： B60Q1/26

    CPC分类号： B60Q1/326

    摘要： A rotary electrical contact device for transferring electrical energy and control signals from a stationary point on a motorcycle to a motorcycle wheel for the purposes of powering a wheel-illuminating display device mounted on a motorcycle wheel such as that device described in U.S. Pat. No. 6,789,928, “Automatic Mechetronic Wheel Light Device”. The present device mounts inconspicuously against the hub of a motorcycle wheel, typically within the space bounded by a motorcycle wheel axel and the inner diameter of a disc brake rotor. The device allows for simultaneous electrical power transmission for multiple electrical circuits. The device comprises a combination of mechanical and electrical components and can be manufactured inexpensively using common materials. The device can be configured for all types of motorcycles types.

    摘要翻译： 一种用于将电能和控制信号从摩托车上的静止点传递到摩托车车轮的旋转电接触装置，用于为安装在摩托车车轮上的车轮照明显示装置提供动力，例如美国专利No. “自动Mechetronic轮灯装置”6,789,928号。 本装置通常在由摩托车车轮轴限定的空间和盘式制动器转子的内径中不明显地安装在摩托车车轮的轮毂上。 该装置允许用于多个电路的同时电力传输。 该装置包括机械和电气部件的组合，并且可以使用普通材料廉价地制造。 该设备可以配置为所有类型的摩托车类型。

    Method and apparatus for managing the configuration and functionality of a semiconductor design
    3.
    发明申请
    Method and apparatus for managing the configuration and functionality of a semiconductor design 审中-公开
    用于管理半导体设计的配置和功能的方法和装置

    公开(公告)号：US20050149898A1

    公开(公告)日：2005-07-07

    申请号：US11067086

    申请日：2005-02-25

    申请人： James Hakewill ,  Mohammed Khan ,  Edward Plowman

    发明人： James Hakewill ,  Mohammed Khan ,  Edward Plowman

    IPC分类号： G06F9/318 ,  G06F9/32 ,  G06F9/38 ,  G06F17/50

    CPC分类号： G06F17/505 ,  G06F9/30145 ,  G06F17/50 ,  G06F17/5045

    摘要： A method of managing the configuration, design parameters, and functionality of an integrated circuit (IC) design using a hardware description language (HDL). Instructions can be added, subtracted, or generated by the designer interactively during the design process, and customized HDL descriptions of the IC design are generated through the use of scripts based on the user-edited instruction set and inputs. The customized HDL description can then be used as the basis for generating “makefiles” for purposes of simulation and/or logic level synthesis. The method further affords the ability to generate an HDL model of a complete device, such as a microprocessor or DSP. A computer program implementing the aforementioned method and a hardware system for running the computer program are also disclosed.

    摘要翻译： 使用硬件描述语言（HDL）管理集成电路（IC）设计的配置，设计参数和功能的方法。 可以在设计过程中交互地添加，减去或生成指令，并且通过使用基于用户编辑的指令集和输入的脚本生成IC设计的定制HDL描述。 然后，可以将定制的HDL描述用作为模拟和/或逻辑级合成的目的生成“makefile”的基础。 该方法进一步提供产生诸如微处理器或DSP的完整设备的HDL模型的能力。 还公开了实现上述方法的计算机程序和用于运行计算机程序的硬件系统。

    2-(1H-4(5)-imidazoyl) cyclopropyl derivatives
    6.
    发明授权
    2-(1H-4(5)-imidazoyl) cyclopropyl derivatives 失效
    2-（1H-4（5） - 咪唑基）环丙基衍生物

    公开(公告)号：US6008240A

    公开(公告)日：1999-12-28

    申请号：US991030

    申请日：1997-12-15

    申请人： James G. Phillips ,  Clark E. Tedford ,  Amin Mohammed Khan ,  Stephen L. Yates ,  Syed M. Ali

    发明人： James G. Phillips ,  Clark E. Tedford ,  Amin Mohammed Khan ,  Stephen L. Yates ,  Syed M. Ali

    IPC分类号： C07D233/54 ,  C07D233/56 ,  C07D233/64 ,  C07D403/12 ,  A61K31/415

    CPC分类号： C07D233/56 ,  C07D233/64 ,  C07D403/12

    摘要： The present invention provides compounds having H.sub.3 histamine receptor antagonist activity of the general formula: ##STR1## R.sub.2 is a hydrogen or a methyl or ethyl group; R.sub.3 is a hydrogen or a methyl or ethyl group;n is 1, 2, 2, 3, 4, 5, or 6; andR.sub.1 is selected from the group consisting of (a) C.sub.3 to C.sub.8 cycloalkyl; (b) phenyl or substituted phenyl; (c) alkyl; (d) heterocyclic; (e) decahydronapthalene; and (f) octahydroindene;with the provisos thatwhen X is H, A can be --CH.sub.2 CH.sub.2 --,--COCH.sub.2 --,--CONH--,--CON(CH.sub.3), CH.dbd.CH, --c.ident.c--,--CH.sub.2 --NH--, --CH.sub.2 --N(CH.sub.3)--,--CH(OH)CH.sub.2 --,--NH--CH.sub.2 --, --N(CH.sub.3)--CH.sub.2 --,--CH.sub.2 O--,--CH.sub.2 S--, and --NHCOO--;when X is NH.sub.2, NH(CH.sub.3), N(CH.sub.3).sub.2, OH, OCH.sub.3, CH.sub.3, SH, and SCH.sub.3 ; A can be --NHCO--, --N(CH.sub.3)--CO--, --NHCH.sub.2 --, --N(CH.sub.3)--CH.sub.2 --, --CH.dbd.CH--; --COCH.sub.2, --CH.sub.2 CH.sub.2 --,--CH(OH)CH.sub.2, or --C.ident.C--; andwhen R.sub.1 and X taken together denote a 5,6 or 6,6 saturated bicyclic ring structure X NH, O, or S and the pharmaceutically acceptable salts, and individual stereoisomers of compounds of structural formula (1.0) above. This invention also provides pharmaceutical compositions comprising a pharmaceutically acceptable carrier in combination with an effective amount of a compound of the above formula and a method of treating conditions in which antagonism of histamine H.sub.3 receptors may be of therapeutic importance.

    摘要翻译： 本发明提供了具有以下通式的H3组胺受体拮抗剂活性的化合物：R2是氢或甲基或乙基; R3是氢或甲基或乙基; n为1,2,3,4,5或6; 并且R 1选自（a）C 3至C 8环烷基; （b）苯基或取代的苯基; （c）烷基; （d）杂环; （e）十氢萘; 和（f）八氢茚; 条件是当X是H时，A可以是-CH 2 CH 2 - ， - COCH 2 - ， - CONH - ， - CON（CH 3），CH = CH，-c = c - ， - CH 2 -NH-， - CH 2 -N （CH 3） - ， - CH（OH）CH 2 - ， - NH-CH 2 - ， - N（CH 3）-CH 2 - ， - CH 2 O - ， - CH 2 S-和-NHCOO-; 当X是NH 2时，NH（CH 3），N（CH 3）2，OH，OCH 3，CH 3，SH和SCH 3; A可以是-NHCO - ， - N（CH 3）-CO - ， - NHCH 2 - ， - N（CH 3）-CH 2 - ， - CH = CH-; -COCH 2，-CH 2 CH 2 - ， - CH（OH）CH 2或-C = C-; 当R1和X一起表示5,6或6,6饱和双环结构X NH，O或S时，以及上述结构式（1.0）化合物的药学上可接受的盐和单独的立体异构体。 本发明还提供药物组合物，其包含药学上可接受的载体与有效量的上述化合物的组合以及治疗其中组胺H3受体的拮抗作用具有治疗意义的病症的方法。

    Potassium ion channel modulators and uses thereof
    8.
    发明授权
    Potassium ion channel modulators and uses thereof 有权

    公开(公告)号：US09464052B2

    公开(公告)日：2016-10-11

    申请号：US13054960

    申请日：2009-07-20

    申请人： Simon David Edwards ,  Meriel Ruth Kimberley ,  Richard Edward Armer ,  Nawaz Mohammed Khan

    发明人： Simon David Edwards ,  Meriel Ruth Kimberley ,  Richard Edward Armer ,  Nawaz Mohammed Khan

    IPC分类号： C07C237/20 ,  C07D213/40

    CPC分类号： A61K31/165 ,  A61K31/198 ,  A61K31/40 ,  A61K31/4402 ,  A61K31/445 ,  A61K31/5375 ,  A61K45/06 ,  C07C237/20 ,  C07D213/40

    摘要： Compounds of formula (I) and pharmacologically acceptable salts and pro-drugs thereof wherein: Ar1 and Ar2 are aryl or heteroaryl; a is 0 to 5; R1 is alkyl, halogen, haloalkyl, alkoxy, haloalkoxy, alkoxycarbonyl, carboxyl, hydroxyl, amino, monoalkylamino, dialkylamino, nitro, acylamino, alkoxycarbonylamino, alkylsulphonyl, alkylsulphonylamino or cyano and, where a is greater than 1, each substituent R1 may be the same or different; b is 0 to 5; R2 is alkyl, halogen, haloalkyl, haloalkoxy, alkoxy, alkoxycarbonyl, carboxyl, hydroxyl, amino, monoalkylamino, dialkylamino, nitro, acylamino, alkoxycarbonylamino, alkylsulphonyl, alkylsulphonylamino or cyano and where b is greater than 1, each substituent R2 may be the same or different; V is selected from the group consisting of (CR3aR3b)pCON(R3b)X and (CR3aR3b)pN(R3b)CO(X), wherein said groups are in the 3- (meta) or 4- (para) position with respect to the substituent Z; W is selected from the group consisting of NR4a, O, S, S═O, SO2 and C(R4aR4b)2; X is hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl, haloalkoxyalkyl, aryloxyalkyl, cycloalkyl, aryl, heteroaryl, polyalkylene glycol, aminoalkyl, monoalkylaminoalkyl, dialkylaminoalkyl, alkyl that is substituted with a groups of formula of formula NR8R9 wherein R8 and R9 together with the nitrogen atom to which they are attached form a saturated or partially unsaturated heterocyclic group, carboxyalkyl, alkoxycarbonylalkyl, haloalkoxycarbonylalkyl or aralkyloxycarbonylalkyl; Y and Z are the same or different and each is a substituent selected from the group consisting of (CR5aR5b)n1, C═O, SO2, C(═O)NR5a; C(═O)NR5aSO2 and C═O(R5aR5b)n2; R3a, R3b, R4a, R4b, R5a and R5b are the same or different and each is selected from the hydrogen, alkyl, cycloalkyl, aryl and heteroaryl; n1 and n2 are the same or different and each is 0 to 2; and p is 0 to 2; are potassium ion channel modulators, making them particularly useful in treating and preventing conditions such as pain, lower urinary tract disorders and the like.

    Coordinating real-world gatherings to promote online community
    10.
    发明授权
    Coordinating real-world gatherings to promote online community 有权
    协调现实世界的聚会，促进在线社区

    公开(公告)号：US08845428B2

    公开(公告)日：2014-09-30

    申请号：US12904077

    申请日：2010-10-13

    申请人： Mohammed Khan

    发明人： Mohammed Khan

    IPC分类号： A63F9/24 ,  A63F13/00 ,  G06F17/00 ,  G06F19/00

    CPC分类号： H04L67/38 ,  G07F17/3272

    摘要： Coordinating real-world gatherings to promote an online community, the method including: encouraging participants of the online community to participate in a real-world gathering by providing incentives for the participants; promoting familiarity among the participants by providing and introducing online community titles of the participants at the real-world gathering; and providing online benefits or rewards to the participants for participating in the real-world gathering. Keywords include socializing in the real world, community building and bridging the gap between the game world and the real world.

    摘要翻译： 协调现实世界的聚会，以促进在线社区，其方法包括：通过为参与者提供奖励来鼓励在线社区的参与者参加现实世界的聚会; 通过在现实世界聚会中提供和介绍参与者的在线社区标题，促进参与者之间的熟悉程度; 并向与会者提供参与现场聚会的在线福利或奖励。 关键词包括社会化现实世界，社区建设，弥合游戏世界与现实世界的差距。