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公开(公告)号:US4994600A
公开(公告)日:1991-02-19
申请号:US869782
申请日:1986-06-02
申请人: Satomi Takahashi , Yasuyoshi Ueda , Yoshifumi Yanagida , Namito Yoshio , Takehisa Ohashi , Kiyoshi Watanabe
发明人: Satomi Takahashi , Yasuyoshi Ueda , Yoshifumi Yanagida , Namito Yoshio , Takehisa Ohashi , Kiyoshi Watanabe
IPC分类号: C07C69/738 , B01J27/02 , B01J31/02 , B01J31/14 , C07B61/00 , C07C67/327
CPC分类号: C07C67/327
摘要: A process for preparing trans-.beta.-benzoylacrylic acid ester having the general formula (I): ##STR1## wherein R is alkyl group or aralkyl group, which comprises dealcoholizing .beta.-benzoyl-.alpha.-alkoxypropionic acid ester having the general formula (II): ##STR2## wherein R is above, in the presence of an acid catalyst to give trans-.beta.-benzoylacrylic acid ester having the general formula (I).According to the process of the present invention, the by-product (II) produced in the esterification reaction of .beta.-benzoylacrylic acid (III) with the alcohol (V) by the dehydration reaction can be converted into the compound (I) by the dealcoholization reaction in the presence of the acid catalyst and thus trans-.beta.-benzoylacrylic acid ester (I) with a high purity can be produced in an industrially advantageous manner.
摘要翻译: 制备具有通式(I)的反式-β-苯甲酰基丙烯酸酯的方法:其中R是烷基或芳烷基,其包括使具有通式(I)的β-苯甲酰基-α-烷氧基丙酸酯脱醇 (II):其中R在上面,在酸催化剂存在下,得到具有通式(I)的反式-β-苯甲酰基丙烯酸酯。 根据本发明的方法,通过脱水反应在β-苯甲酰基丙烯酸(III)与醇(V)的酯化反应中产生的副产物(II)可以通过 在酸催化剂存在下脱醇反应,从而可以以工业上有利的方式生产具有高纯度的反式-β-苯甲酰基丙烯酸酯(I)。