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公开(公告)号:US06713645B1
公开(公告)日:2004-03-30
申请号:US09688106
申请日:2000-10-13
申请人: Nicholas James Bach , Susan Elizabeth Draheim , Robert Delane Dillard , Edward David Mihelich , Jason Scott Sawyer , Douglas Wade Beight , Michael LeRoy Phillips , Tulio Suarez , Daniel Jon Sall , Jolie Anne Bastian , Michael Lyle Denney , Gary Alan Hite , Michael Dean Kinnick , Robert Theodore Vasileff , John Michael Morin, Jr. , Ho-Shen Lin , Michael Enrico Richett , Richard Waltz Harper , John McNeill McGill, III , Benjamin Alan Anderson , Nancy Kay Harn , Richard James Loncharich , Richard Walter Schevitz
发明人: Nicholas James Bach , Susan Elizabeth Draheim , Robert Delane Dillard , Edward David Mihelich , Jason Scott Sawyer , Douglas Wade Beight , Michael LeRoy Phillips , Tulio Suarez , Daniel Jon Sall , Jolie Anne Bastian , Michael Lyle Denney , Gary Alan Hite , Michael Dean Kinnick , Robert Theodore Vasileff , John Michael Morin, Jr. , Ho-Shen Lin , Michael Enrico Richett , Richard Waltz Harper , John McNeill McGill, III , Benjamin Alan Anderson , Nancy Kay Harn , Richard James Loncharich , Richard Walter Schevitz
IPC分类号: C07C6976
CPC分类号: C07D409/04 , C07D209/88 , C07F9/5728
摘要: A class of novel tricyclics is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.
摘要翻译: 公开了一类新型三环类药物,以及这些化合物用于抑制sPLA2介导的脂肪酸释放以治疗诸如败血性休克的病症。
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2.
公开(公告)号:US06380397B1
公开(公告)日:2002-04-30
申请号:US09787587
申请日:2001-03-19
IPC分类号: C07D20904
CPC分类号: C07D209/22
摘要: A process for preparing 1H-indole-3-glyoxamides useful for inhibiting SPLA2 and novel intermediates useful in the preparation of such compounds.
摘要翻译: 用于制备可用于抑制SPLA2的1H-吲哚-3-乙酰氧基酰胺的方法和可用于制备这些化合物的新中间体。
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3.
公开(公告)号:US06265591B1
公开(公告)日:2001-07-24
申请号:US09647471
申请日:2000-09-27
IPC分类号: C07D20912
CPC分类号: C07D209/30 , C07D209/22 , Y02P20/55
摘要: A process for preparing 1H-indole-3-glyoxamides useful for inhibiting SPLA2 and novel intermediates useful in the preparation of such compounds.
摘要翻译: 用于制备可用于抑制SPLA2的1H-吲哚-3-乙酰氧基酰胺的方法和可用于制备这些化合物的新中间体。
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公开(公告)号:US06570023B1
公开(公告)日:2003-05-27
申请号:US09787586
申请日:2001-03-19
IPC分类号: C07D20904
CPC分类号: C07D209/08 , C07D209/12
摘要: A process for preparing novel compounds useful in the preparation of 1H-indole-3-glyoxamides.
摘要翻译: 制备可用于制备1H-吲哚-3-乙酰氧基酰胺的新型化合物的方法
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公开(公告)号:US06617460B1
公开(公告)日:2003-09-09
申请号:US10351642
申请日:2003-01-24
IPC分类号: C07D27102
CPC分类号: C07C313/04 , C07D209/08
摘要: A process for preparing novel compounds useful in the preparation of 1H-indole-3-glyoxamides.
摘要翻译: 制备可用于制备1H-吲哚-3-乙酰氧基酰胺的新型化合物的方法。
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6.Process for preparing 4-hdyroxy indole, indazole and carbazole compounds 失效
标题翻译: 4-羟基吲哚,吲唑和咔唑化合物的制备方法公开(公告)号:US06407261B1
公开(公告)日:2002-06-18
申请号:US09647470
申请日:2000-09-27
IPC分类号: C07D20908
CPC分类号: C07C313/04 , C07D209/08 , C07D209/88
摘要: A process for preparing 4-hydroxy carbazoles useful as intermediates for preparing compounds that are useful for inhibiting sPLA2 and novel intermediates.
摘要翻译: 用作制备可用于抑制sPLA2和新型中间体的化合物的中间体的4-羟基咔唑的制备方法。
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公开(公告)号:US06177440B1
公开(公告)日:2001-01-23
申请号:US09063066
申请日:1998-04-21
申请人: Nicholas James Bach , Susan Elizabeth Draheim , Robert Delane Dillard , Edward David Mihelich , Jason Scott Sawyer , Douglas Wade Beight , Michael LeRoy Phillips , Tulio Suarez , Daniel Jon Sall , Jolie Anne Bastian , Michael Lyle Denney , Gary Alan Hite , Michael Dean Kinnick , Robert Theodore Vasileff , John Michael Morin, Jr. , Ho-Shen Lin , Michael Enrico Richett , Richard Waltz Harper , John McNeill McGill, III , Benjamin Alan Anderson , Nancy Kay Harn , Richard James Loncharich , Richard Walter Schevitz
发明人: Nicholas James Bach , Susan Elizabeth Draheim , Robert Delane Dillard , Edward David Mihelich , Jason Scott Sawyer , Douglas Wade Beight , Michael LeRoy Phillips , Tulio Suarez , Daniel Jon Sall , Jolie Anne Bastian , Michael Lyle Denney , Gary Alan Hite , Michael Dean Kinnick , Robert Theodore Vasileff , John Michael Morin, Jr. , Ho-Shen Lin , Michael Enrico Richett , Richard Waltz Harper , John McNeill McGill, III , Benjamin Alan Anderson , Nancy Kay Harn , Richard James Loncharich , Richard Walter Schevitz
IPC分类号: A61K3144
CPC分类号: C07D209/88
摘要: A class of novel tricyclics is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.
摘要翻译: 公开了一类新型三环类药物,以及这些化合物用于抑制sPLA2介导的脂肪酸释放以治疗诸如败血性休克的病症。
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