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公开(公告)号:US20080249060A1
公开(公告)日:2008-10-09
申请号:US12123310
申请日:2008-05-19
IPC分类号: A61K31/706 , C07H19/20 , C07H19/16 , A61P31/14
摘要: Disclosed are compounds, compositions and methods for treating hepatitis C virus infections.
摘要翻译: 公开了用于治疗丙型肝炎病毒感染的化合物,组合物和方法。
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公开(公告)号:US07414031B2
公开(公告)日:2008-08-19
申请号:US11280984
申请日:2005-11-15
CPC分类号: A61K31/7076 , A61K38/21 , C07H19/14 , C07H19/22 , A61K2300/00
摘要: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
摘要翻译: 公开了用于治疗由黄病毒科家族病毒(例如丙型肝炎病毒)引起的病毒感染的化合物,组合物和方法。
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公开(公告)号:US20090036399A1
公开(公告)日:2009-02-05
申请号:US12206581
申请日:2008-09-08
IPC分类号: A61K31/7064 , A61P31/12
CPC分类号: C07H19/00 , C07H19/167
摘要: Disclosed are methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Such compounds are represented by Formula I as follows: wherein W, W1, W2, Y, R1, Z, Y′ and R are as defined herein.
摘要翻译: 公开了用于治疗由黄病毒科家族病毒(例如丙型肝炎病毒)引起的病毒感染的方法。 这样的化合物由式I表示如下:其中W,W 1,W 2,Y,R 1,Z,Y'和R如本文所定义。
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公开(公告)号:US07432248B2
公开(公告)日:2008-10-07
申请号:US11492558
申请日:2006-07-24
IPC分类号: A61K31/70 , C07H19/14 , C07H19/207
CPC分类号: C07H19/00 , C07H19/167
摘要: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Such compounds are represented by Formula I as follows: wherein W, W1, W2, Y, R1, Z, Y′ and R are as defined herein.
摘要翻译: 公开了用于治疗由黄病毒科家族病毒(例如丙型肝炎病毒)引起的病毒感染的化合物,组合物和方法。 这样的化合物由式I表示如下:其中W,W 1,W 2,Y,R 1,Z,Y'和 R如本文所定义。
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公开(公告)号:US07405204B2
公开(公告)日:2008-07-29
申请号:US11411434
申请日:2006-04-25
CPC分类号: A61K31/7076 , C07H19/00 , C07H19/14 , A61K2300/00
摘要: Disclosed are compounds, compositions and methods for treating viral infections caused by a Flaviviridae family virus, such as hepatitis C virus.
摘要翻译: 公开了用于治疗由黄病毒科家族病毒(例如丙型肝炎病毒)引起的病毒感染的化合物,组合物和方法。
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6.
公开(公告)号:US06849713B2
公开(公告)日:2005-02-01
申请号:US09892327
申请日:2001-06-26
申请人: Wentao Zhang , Sebastian Johannes Reinhard Liehr , Mark Douglas Velligan , Natalia B. Dyatkina , Janos Botyanszki , Dong-Fang Shi , Christopher Don Roberts , Alexander Khorlin , Peter Harold Nelson , Joseph Martin Muchowski
发明人: Wentao Zhang , Sebastian Johannes Reinhard Liehr , Mark Douglas Velligan , Natalia B. Dyatkina , Janos Botyanszki , Dong-Fang Shi , Christopher Don Roberts , Alexander Khorlin , Peter Harold Nelson , Joseph Martin Muchowski
IPC分类号: A61K31/395 , A61K31/40 , A61K31/404 , A61K31/4439 , A61K31/496 , A61K31/506 , A61P31/00 , A61P31/04 , A61P31/10 , A61P35/00 , A61P43/00 , C07D207/34 , C07D209/42 , C07D209/88 , C07D401/14 , C07D403/14 , C07D409/14 , A61K38/04
CPC分类号: C07D401/14 , C07D207/34 , C07D209/42 , C07D403/14 , C07D409/14
摘要: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.
摘要翻译: 本发明提供了具有以下一种或多种活性的新型化合物:抗菌,抗真菌和抗肿瘤活性。 所述化合物具有式(I):还提供了含有这些化合物的药物组合物,制备方法和使用这些化合物的方法。
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公开(公告)号:US07629328B2
公开(公告)日:2009-12-08
申请号:US12206581
申请日:2008-09-08
CPC分类号: C07H19/00 , C07H19/167
摘要: Disclosed are methods for treating hepatitis C viral infections using deaza-purine compounds of Formula I: wherein W, W1, W2, Y, R1, Z, Y′ and R are as defined herein.
摘要翻译: 公开了使用式I的去氮嘌呤化合物治疗丙型肝炎病毒感染的方法:其中W,W1,W2,Y,R1,Z,Y'和R如本文所定义。
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公开(公告)号:US07157434B2
公开(公告)日:2007-01-02
申请号:US10970321
申请日:2004-10-20
CPC分类号: C07H19/14
摘要: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Such compounds are represented by Formula I as follows: wherein, Y, W, W1 and W2 are as defined herein.
摘要翻译: 公开了用于治疗由黄病毒科家族病毒(例如丙型肝炎病毒)引起的病毒感染的化合物,组合物和方法。 这样的化合物由式I表示如下:其中Y,W,W 1和W 2如本文所定义。
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公开(公告)号:US07629320B2
公开(公告)日:2009-12-08
申请号:US12123310
申请日:2008-05-19
摘要: Disclosed are β-D-ribofuranosyl-pyrazolo[3,4-d]pyrimidine compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Representative compounds include those having the general formula.
摘要翻译: 公开了β-D-呋喃核糖基 - 吡唑并[3,4-d]嘧啶化合物,用于治疗由黄病毒科家族病毒(例如丙型肝炎病毒)引起的病毒感染的组合物和方法。 代表性的化合物包括具有通式的化合物。
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10.
公开(公告)号:US07425547B2
公开(公告)日:2008-09-16
申请号:US10676956
申请日:2003-09-30
IPC分类号: A61K31/70 , C07H19/167 , C07H19/20
摘要: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Such compounds are represented by Formula IB as follows: and pharmaceutically acceptable prodrugs and salts thereof, where R, R1, R13, R14, W, W2, W3, Y and Z are as defined herein.
摘要翻译: 公开了用于治疗由黄病毒科家族病毒(例如丙型肝炎病毒)引起的病毒感染的化合物,组合物和方法。 这样的化合物由式IB表示如下:及其药学上可接受的前药和盐,其中R 1,R 1,R 13,R 14, ,W,W 2,W 3,Y和Z如本文所定义。
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