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公开(公告)号：US10392578B2
公开(公告)日：2019-08-27
申请号：US13151014
申请日：2011-06-01
申请人： Stephen Robert Cherinko , Robert Cody Kertis , Kirk E. Apt , Paul Warren Behrens , Jon Milton Hansen , Joseph W. Pfeifer, III , Tracey Lynn Stahl , Ross Zirkle , Nasrin Tabayeh Burke , Krishna Raman , Neil Francis Leininger
发明人： Stephen Robert Cherinko , Robert Cody Kertis , Kirk E. Apt , Paul Warren Behrens , Jon Milton Hansen , Joseph W. Pfeifer, III , Tracey Lynn Stahl , Ross Zirkle , Nasrin Tabayeh Burke , Krishna Raman , Neil Francis Leininger
摘要： The present invention relates to processes for obtaining a lipid from a cell by lysing the cell, contacting the cell with a base and/or salt, and separating the lipid. The present invention is also directed to a lipid prepared by the processes of the present invention. The present invention is also directed to microbial lipids having a particular anisidine value, peroxide value, and/or phosphorus content.
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公开(公告)号：US20190249108A1
公开(公告)日：2019-08-15
申请号：US16309632
申请日：2017-07-12
申请人： Stephen Robert CHERINKO , Matthias DERNEDDE , Xiao Daniel DONG , Michael Benjamin JOHNSON , Robert Cody KERTIS , Jochen LEBERT , Neil Francis LEININGER , Kirt Lyvell MATTHEWS , Holger PFEIFER , Horst PRIEFERT , Christian RABE , Shannon Elizabeth Ethier RESOP , Joachim WINDAU , Daniel VERKOEIJEN , Gabriel ZAVODSKY , DSM IP Assets B.V. , Evonik Degussa GmbH
发明人： Stephen Robert CHERINKO , Matthias DERNEDDE , Michael DIEHL , Xiao Daniel DONG , Michael Benjamin JOHNSON , Robert Cody KERTIS , Jochen LEBERT , Neil Francis LEININGER , Kirt Lyvell MATTHEWS , Holger PFEIFER , Horst PRIEFERT , Christian RABE , Shannon Elizabeth Ethier RESOP , Joachim WINDAU , Daniel VERKOEIJEN , Gabriel ZAVODSKY
CPC分类号： C11B1/10 , A23K10/12 , A23K20/158 , C07C51/48 , C11B1/02 , C11B1/025 , C11B1/14 , C11B3/16 , C12N1/06 , C12P7/6427 , C12P7/6472 , C07C57/02
摘要： The processes for obtaining a microbial oil comprising one or more polyunsaturated fatty acids (PUFAs) from one or more microbial cells comprise removing water from the cell fermentation broth or lysed cell composition before demulsification is conducted. Such a process has the benefits of reduced demulsification time and reduced salt use. Microbial oil comprising one or more PUFAs can be recovered from microbial cells by the process.
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公开(公告)号：US20160319218A1
公开(公告)日：2016-11-03
申请号：US15106379
申请日：2014-12-19
摘要： Disclosed herein are processes for obtaining a microbial oil comprising one or more polyunsaturated fatty acids (PUFAs) from one or more microbial cells by lysing the cells to form a lysed cell composition, treating the lysed cell composition to form an oil-containing emulsion and then recovering the oil from the oil-containing emulsion. Further disclosed herein is microbial oil comprising one or more PUFAs that is recovered from microbial cells by at least one process described herein.
摘要翻译： 本文公开了通过裂解细胞以形成裂解的细胞组合物来获得包含来自一种或多种微生物细胞的一种或多种多不饱和脂肪酸（PUFA）的微生物油的方法，处理裂解的细胞组合物以形成含油乳液，然后 从含油乳液中回收油。 本文进一步公开的是包含通过本文所述的至少一种方法从微生物细胞回收的一种或多种PUFA的微生物油。
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公开(公告)号：US20160319217A1
公开(公告)日：2016-11-03
申请号：US15106375
申请日：2014-12-19
申请人： Brock TRIPLETT , Micah NEEDHAM , Nasrin TABAYEHNEJAD , Ginger SHANK , Kirt Lyvell MATTHEWS, Sr. , John HOGAN , Mark BARKER , Neil Francis LEININGER
发明人： Brock TRIPLETT , Micah NEEDHAM , Nasrin TABAYEHNEJAD , Ginger SHANK , Kirt Lyvell MATTHEWS, Sr. , John HOGAN , Mark BARKER , Neil Francis LEININGER
摘要： Disclosed herein are processes for obtaining a microbial oil comprising one or more polyunsaturated fatty acids (PUFAs) from one or more microbial cells by lysing the cells to form a lysed cell composition and then recovering the oil from the lysed cell composition. Further disclosed herein is microbial oil comprising one or more PUFAs that is recovered from microbial cells by at least one process described herein.
摘要翻译： 本文公开了通过裂解细胞以形成裂解的细胞组合物，然后从裂解的细胞组合物中回收油从而获得来自一种或多种微生物细胞的一种或多种多不饱和脂肪酸（PUFA）的微生物油的方法。 本文进一步公开的是包含通过本文所述的至少一种方法从微生物细胞回收的一种或多种PUFA的微生物油。
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公开(公告)号：US20110295028A1
公开(公告)日：2011-12-01
申请号：US13151014
申请日：2011-06-01
申请人： Stephen Robert Cherinko , Robert Cody Kertis , Kirk E. Apt , Paul Warren Behrens , Jon Milton Hansen , Joseph W. Pfeifer, III , Tracey Lynn Stahl , Ross Zirkle , Nasrin Tabayeh Burke , Krishna Raman , Neil Francis Leininger
发明人： Stephen Robert Cherinko , Robert Cody Kertis , Kirk E. Apt , Paul Warren Behrens , Jon Milton Hansen , Joseph W. Pfeifer, III , Tracey Lynn Stahl , Ross Zirkle , Nasrin Tabayeh Burke , Krishna Raman , Neil Francis Leininger
摘要： The present invention relates to processes for obtaining a lipid from a cell by lysing the cell, contacting the cell with a base and/or salt, and separating the lipid. The present invention is also directed to a lipid prepared by the processes of the present invention. The present invention is also directed to microbial lipids having a particular anisidine value, peroxide value, and/or phosphorus content.
摘要翻译： 本发明涉及通过裂解细胞，使细胞与碱和/或盐接触并分离脂质从细胞获得脂质的方法。 本发明还涉及通过本发明的方法制备的脂质。 本发明还涉及具有特定茴香胺值，过氧化值和/或磷含量的微生物脂质。
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公开(公告)号：US20160318840A1
公开(公告)日：2016-11-03
申请号：US15106371
申请日：2014-12-19
申请人： Mark BARKER , Nasrin TABAYEHNEJAD , Ginger SHANK , Neil Francis LEININGER , Kirt Lyvell MATTHEWS, Sr.
发明人： Mark BARKER , Nasrin TABAYEHNEJAD , Ginger SHANK , Neil Francis LEININGER , Kirt Lyvell MATTHEWS, Sr.
摘要： Disclosed herein are processes for obtaining a microbial oil comprising one or more polyunsaturated fatty acids (PU-FAs) from one or more microbial cells by lysing the cells to form a lysed cell composition and then recovering the oil from the lysed cell composition. Further disclosed herein is microbial oil comprising one or more PUFAs that is recovered from microbial cells by at least one process described herein.
摘要翻译： 本文公开了通过裂解细胞以形成裂解的细胞组合物，然后从裂解的细胞组合物中回收油来获得包含来自一种或多种微生物细胞的一种或多种多不饱和脂肪酸（PU-FAs）的微生物油的方法。 本文进一步公开的是包含通过本文所述的至少一种方法从微生物细胞回收的一种或多种PUFA的微生物油。
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7.发明授权Polyunsaturated fatty acid-containing oil product and uses and production thereof 有权多不饱和脂肪酸油产品及其用途及生产公开(公告)号：US08753707B2
公开(公告)日：2014-06-17
申请号：US11748330
申请日：2007-05-14
IPC分类号： A23D9/02
CPC分类号： A23D7/04 , A23D7/06 , A23D9/013 , A23D9/04 , A23D9/06 , A61K47/12 , C11B1/025 , C11B1/10 , C11B3/001 , C11B3/008 , C11B3/08 , C11B3/10 , C11B5/0092 , C11B7/0075 , C11B15/00
摘要： The present invention includes a solid fat composition that includes an oil having saturated fat and a microbial oil having a long chain polyunsaturated fatty acid and an emulsifier. In particular, the solid fat composition can have high levels of long chain polyunsaturated fatty acid and low amounts of emulsifiers. In preferred embodiments, the polyunsaturated oil is an unwinterized microbial oil. The invention also relates to methods for making such compositions and food, nutritional, and pharmaceutical products comprising said compositions. The present invention also includes a microbial oil product prepared by extracting an oil-containing fraction comprising at least one LC-PUFA from a microbial biomass, and treating the fraction by a process of vacuum evaporation, wherein the oil product has not been subject to one or more of a solvent winterization step, a caustic refining process, a chill filtration process, or a bleaching process.
摘要翻译： 本发明包括具有饱和脂肪的油和具有长链多不饱和脂肪酸和乳化剂的微生物油的固体脂肪组合物。 特别地，固体脂肪组合物可以具有高水平的长链多不饱和脂肪酸和少量的乳化剂。 在优选的实施方案中，多不饱和的油是未连续的微生物油。 本发明还涉及制备这种组合物的方法以及包含所述组合物的食品，营养和药物产品。 本发明还包括通过从微生物生物质提取包含至少一种LC-PUFA的含油馏分制备的微生物油产物，并通过真空蒸发处理该馏分，其中该油产品未被一个 或更多的溶剂冬季化步骤，苛性碱精炼方法，冷却过滤方法或漂白方法。
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公开(公告)号：US20160340287A1
公开(公告)日：2016-11-24
申请号：US15106368
申请日：2014-12-19
申请人： Nasrin TABAYEHNEJAD , Stephen CHERINKO , Mark BARKER , Neil Francis LEININGER , DSM IP ASSETS B.V. , David MCCLEMENTS
摘要： Disclosed are processes for obtaining a microbial oil comprising one or more polyunsaturated fatty acids (PUFAs) from one or more microbial cells by lysing the cells to form a lysed cell composition and then recovering the oil from the lysed cell composition. Further disclosed is microbial oil comprising one or more PUFAs that is recovered from microbial cells by at least one process described.
摘要翻译： 公开了通过裂解细胞以形成裂解的细胞组合物，然后从裂解的细胞组合物中回收油来从一种或多种微生物细胞获得含有一种或多种多不饱和脂肪酸（PUFA）的微生物油的方法。 还公开了包含一种或多种通过至少一种所述方法从微生物细胞回收的PUFA的微生物油。
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9.发明申请"Polyunsaturated Fatty Acid-Containing Oil Product and Uses and Production Thereof" 审中-公开“多不饱和脂肪酸含油产品及其用途及其生产”公开(公告)号：US20080107791A1
公开(公告)日：2008-05-08
申请号：US11470996
申请日：2006-09-07
申请人： Jaouad Fichtali , Neil Francis Leininger , Jesus Ruben Abril , Naseer Ahmed , S.P. Janaka Namal Senanayake
发明人： Jaouad Fichtali , Neil Francis Leininger , Jesus Ruben Abril , Naseer Ahmed , S.P. Janaka Namal Senanayake
IPC分类号： A23D7/00
CPC分类号： A23D7/04 , A23D7/06 , A23D9/013 , A23D9/04 , A23D9/06 , A61K47/12 , C11B1/025 , C11B1/10 , C11B3/001 , C11B3/008 , C11B3/08 , C11B3/10 , C11B5/0092 , C11B7/0075 , C11B15/00
摘要： The present invention includes a solid fat composition that includes an oil having saturated fat and a microbial oil having a long chain polyunsaturated fatty acid and an emulsifier. In particular, the solid fat composition can have high levels of long chain polyunsaturated fatty acid and low amounts of emulsifiers. In preferred embodiments, the polyunsaturated oil is an unwinterized microbial oil. The invention also relates to methods for making such compositions and food, nutritional, and pharmaceutical products comprising said compositions. The present invention also includes a microbial oil product prepared by extracting an oil-containing fraction comprising at least one LC-PUFA from a microbial biomass, and treating the fraction by a process of vacuum evaporation, wherein the oil product has not been subject to one or more of a solvent winterization step, a caustic refining process, a chill filtration process, or a bleaching process.
摘要翻译： 本发明包括具有饱和脂肪的油和具有长链多不饱和脂肪酸和乳化剂的微生物油的固体脂肪组合物。 特别地，固体脂肪组合物可以具有高水平的长链多不饱和脂肪酸和少量的乳化剂。 在优选的实施方案中，多不饱和的油是未连续的微生物油。 本发明还涉及制备这种组合物的方法以及包含所述组合物的食品，营养和药物产品。 本发明还包括通过从微生物生物质提取包含至少一种LC-PUFA的含油馏分制备的微生物油产物，并通过真空蒸发处理该馏分，其中该油产品未被一个 或更多的溶剂冬季化步骤，苛性碱精炼方法，冷却过滤方法或漂白方法。
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