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公开(公告)号:US09724475B2
公开(公告)日:2017-08-08
申请号:US13203707
申请日:2010-01-27
申请人: Peter Krulevitch , Ulrich Kraft , Robert Wilk , Zara Sieh , Mitch Zhao
发明人: Peter Krulevitch , Ulrich Kraft , Robert Wilk , Zara Sieh , Mitch Zhao
CPC分类号: A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要: Various embodiments of a “smart” drug delivery pen are provided which include a drug delivery pen having an inertial sensor or accelerometer. A system is also provided that includes the smart drug pen in conjunction with a data management unit(s) DMU. Various exemplary methods for use of the pens and systems are also described and illustrated.
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公开(公告)号:US20120004637A1
公开(公告)日:2012-01-05
申请号:US13203697
申请日:2010-01-27
申请人: Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh , David Price
发明人: Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh , David Price
CPC分类号: A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要: Various embodiments of a “smart” drug delivery system are provided which includes an add-on module and a reusable or disposable drug pen in conjunction with a data management unit(s) DMU. Upon attachment to the pen, the add-on module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reuse of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module. Methods of using the drug delivery system are also described.
摘要翻译: 提供了“智能”药物递送系统的各种实施例,其包括与数据管理单元DMU结合的附加模块和可重复使用或一次性药物笔。 附加模块可以:确定所选择的剂量,所选剂量的注射,注射持续时间,注射时间,笔是否被引发或摇动以充分混合胰岛素混合物,传送与胰岛素相关的信息 剂量和注射到数据管理单元,提供提醒,错误警告或关于针的不正确使用或重复使用的信息,笔上留下的药物的轨迹量或笔的使用持续时间,关于药物到期的时间,或 提供用于定位放错的笔和模块的声音报警器。 还描述了使用药物递送系统的方法。
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公开(公告)号:US07666287B2
公开(公告)日:2010-02-23
申请号:US11614517
申请日:2006-12-21
申请人: Mingqi Zhao , Mark Huang , Stan Thomas , Peter Krulevitch
发明人: Mingqi Zhao , Mark Huang , Stan Thomas , Peter Krulevitch
IPC分类号: G01N27/27
CPC分类号: F04B17/00 , B29C45/14778 , B29C47/0021 , B29C47/065 , B29C47/067 , B29C70/685 , B29K2023/06 , B29K2023/083 , B29K2023/12 , B29K2025/00 , B29K2027/16 , B29K2031/04 , B29K2067/00 , B29K2075/00 , B29K2077/00 , B29K2079/085 , B29K2081/06 , B29L2031/755 , F04B19/006 , Y10T29/49236 , Y10T137/206 , Y10T156/10 , Y10T156/1039 , Y10T156/1052 , Y10T156/1092
摘要: A method for preparing an electrokinetic element is provided and generally includes providing a porous membrane adapted for use in an electrokinetic pump and encapsulating the porous membrane within a polymer substrate to yield an electrokinetic element base member having the porous membrane encapsulated by the polymer. In one embodiment, the method can include laminating the porous membrane between opposed sheets of a polymer before the step of encapsulating. The method can also include cutting the electrokinetic element base member into a plurality of slices and assembling an electrokinetic infusion pump by inserting a slice into a chamber of the pump.
摘要翻译: 提供了一种制备电动元件的方法,并且通常包括提供适用于电动泵中的多孔膜并将多孔膜封装在聚合物基底内以产生具有被聚合物包封的多孔膜的电动元件基底构件。 在一个实施方案中,该方法可以包括在封装步骤之前将多孔膜层叠在聚合物的相对片之间。 该方法还可以包括将动电元件基底部件切割成多个切片,并通过将切片插入泵的腔室来组装电动输注泵。
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公开(公告)号:US20090112185A1
公开(公告)日:2009-04-30
申请号:US12261450
申请日:2008-10-30
申请人: Peter Krulevitch , Frank Cichocki , Lorin P. Olson
发明人: Peter Krulevitch , Frank Cichocki , Lorin P. Olson
IPC分类号: A61M25/00
CPC分类号: A61M5/158 , A61M5/3286 , A61M5/3287 , A61M5/329 , A61M25/00 , A61M25/0068 , A61M2005/1585 , A61M2005/1587 , A61M2205/0266
摘要: A medical device includes a medical device flexible conduit that has an elongated Nitinol strip with a distal end, a proximal end, a longitudinal axis running from the distal end to the proximal end, a sharp head extending from the distal end, and a channel etched therein. Moreover, the channel is dispositioned along the longitudinal axis. The medical device flexible conduit also has a flexible tube at least partially jacketing the elongated Nitinol strip between the distal end and the proximal end, with the channel and the flexible tube defining a conduit. The medical device also includes an insertion mechanism configured to insert a portion of the flexible conduit, including the sharp head, into a user's target site such that the conduit provides fluid communication to the target site.
摘要翻译: 医疗装置包括医疗装置柔性导管,其具有细长的镍钛诺带,其具有远端,近端,从远端延伸到近端的纵向轴线,从远端延伸的尖头,以及蚀刻的通道 其中。 此外,通道沿着纵向轴线布置。 医疗器械柔性导管还具有柔性管,其至少部分地将细长的镍钛诺带夹在远端和近端之间,通道和柔性管限定导管。 该医疗装置还包括插入机构,该插入机构构造成将包括尖头的柔性导管的一部分插入使用者的目标部位,使得导管向目标部位提供流体连通。
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公开(公告)号:US20090112169A1
公开(公告)日:2009-04-30
申请号:US12260773
申请日:2008-10-29
申请人: Peter KRULEVITCH , Frank Cichocki , Lorin P. Olson
发明人: Peter KRULEVITCH , Frank Cichocki , Lorin P. Olson
CPC分类号: A61M5/158 , A61B10/0045 , A61B17/3468 , A61B2010/008 , A61B2017/00867 , A61M5/329 , A61M2005/1585 , A61M2005/1587 , A61M2205/0266 , Y10T29/49
摘要: A medical device flexible conduit includes an elongated Nitinol strip with a distal end, a proximal end, a longitudinal axis running from the distal end to the proximal end, a sharp head extending from the distal end, and a channel etched therein. Moreover, the channel is dispositioned along the longitudinal axis. The medical device flexible conduit also includes a flexible tube at least partially jacketing the elongated Nitinol strip between the distal end and the proximal end with the channel and the flexible tube defining a conduit. A method for manufacturing a medical device flexible conduit includes etching a channel into an elongated Nitinol strip and forming a sharp head on a distal end of the elongated Nitinol strip. The method also includes subsequently jacketing the flat elongated Nitinol strip with a flexible tube such that the flexible tube and channel define a conduit.
摘要翻译: 医疗装置柔性导管包括细长的镍钛诺带,其具有远端,近端,从远端延伸到近端的纵向轴线,从远端延伸的尖头和在其中蚀刻的通道。 此外,通道沿着纵向轴线布置。 医疗器械柔性导管还包括柔性管,其至少部分地将细长的镍钛诺带夹在远端和近端之间,通道和柔性管限定导管。 用于制造医疗器械柔性导管的方法包括将通道蚀刻成细长的镍钛诺带并在细长的镍钛诺带的远端上形成锋利的头部。 该方法还包括随后用柔性管将扁平细长的镍钛诺带材包起来,使得柔性管和通道限定导管。
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公开(公告)号:US20090112155A1
公开(公告)日:2009-04-30
申请号:US12261426
申请日:2008-10-30
申请人: Mitch Zhao , Peter Krulevitch , David Knight , Anthony Lam , Sean O'Connor
发明人: Mitch Zhao , Peter Krulevitch , David Knight , Anthony Lam , Sean O'Connor
CPC分类号: A61M5/14212 , A61M5/14224 , A61M5/16831 , A61M2205/0294 , F04B43/02 , F04B43/043 , F04B43/046
摘要: The invention relates to micropumps for infusing fluids. More specifically, the present disclosure describes and illustrates a micropump design that may be useful for infusing insulin into a diabetic patient. The disclosed design employs a pump chamber that has a diaphragm and a plurality of check valves that are configured to avoid leakage from the reservoir through the pump engine and into an infusion device and, also, to ensure the complete, accurate evacuation of the pump chamber.
摘要翻译: 本发明涉及用于输注流体的微型泵。 更具体地,本公开描述并示出了可用于将胰岛素注入糖尿病患者的微型泵设计。 所公开的设计采用具有隔膜和多个止回阀的泵室,所述多个止回阀被构造成避免从储存器通过泵发动机泄漏并进入输液装置,并且还确保泵室的完全,精确的排空 。
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公开(公告)号:US20080312600A1
公开(公告)日:2008-12-18
申请号:US12138115
申请日:2008-06-12
申请人: Peter Krulevitch , Lorin P. Olson , Zara Sieh , Donna Savage
发明人: Peter Krulevitch , Lorin P. Olson , Zara Sieh , Donna Savage
IPC分类号: A61M5/00
CPC分类号: A61M5/158 , A61M5/3275 , A61M5/329 , A61M25/0009 , A61M25/0068 , A61M25/007 , A61M2005/1585 , A61M2005/1587 , A61M2205/0266
摘要: A flexible medical device conduit includes an elongated framework formed from a flexible material (e.g., Nitinol) with a body portion, sharp head, distal end and proximal end. The flexible medical device conduit also includes a flexible tube at least partially jacketing the elongated framework between the distal end and the proximal end. Moreover, the sharp head is disposed at the distal end and is configured for subcutaneous skin insertion and the elongated framework and flexible tube define at least one conduit between the elongated framework and the flexible tube, the conduit having an opening at the distal end.
摘要翻译: 柔性医疗装置导管包括由柔性材料(例如镍钛诺)形成的细长骨架,其具有主体部分,尖头,远端和近端。 柔性医疗装置导管还包括柔性管,至少部分地将细长骨架夹在远端和近端之间。 此外,尖头设置在远端并且构造成用于皮下皮肤插入,并且细长骨架和柔性管在细长框架和柔性管之间限定至少一个导管,该导管在远端具有开口。
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公开(公告)号:US20060113537A1
公开(公告)日:2006-06-01
申请号:US11326967
申请日:2006-01-05
申请人: Peter Krulevitch , Mariam Maghribi , William Benett , Julie Hamilton , Klint Rose , James Davidson , Mark Strauch
发明人: Peter Krulevitch , Mariam Maghribi , William Benett , Julie Hamilton , Klint Rose , James Davidson , Mark Strauch
IPC分类号: H01L31/0376
CPC分类号: H01L25/165 , B81C1/0023 , H01L21/6835 , H01L31/048 , H01L31/0543 , H01L2221/68345 , H01L2924/0002 , H01L2924/09701 , H01L2924/19041 , H01L2924/19105 , Y02E10/52 , H01L2924/00
摘要: A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.
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公开(公告)号:US20160089503A1
公开(公告)日:2016-03-31
申请号:US14959701
申请日:2015-12-04
申请人: Lorin Olson , Vaclav Vojan , Juergen Ernst Pfrang , Peter Krulevitch , Jingli Wang , Nicholas Foley , Mingqi Zhao , Paul Tashjian
发明人: Lorin Olson , Vaclav Vojan , Juergen Ernst Pfrang , Peter Krulevitch , Jingli Wang , Nicholas Foley , Mingqi Zhao , Paul Tashjian
CPC分类号: A61M5/326 , A61M5/20 , A61M5/2033 , A61M5/2046 , A61M5/2053 , A61M5/3129 , A61M5/315 , A61M5/31511 , A61M5/3157 , A61M5/3204 , A61M5/3213 , A61M5/3243 , A61M5/3287 , A61M5/50 , A61M5/5086 , A61M2005/2013 , A61M2005/2026 , A61M2005/2073 , A61M2005/208 , A61M2005/3123 , A61M2005/3125 , A61M2005/3126 , A61M2005/3247 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/584 , A61M2205/586
摘要: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.
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公开(公告)号:US08556867B2
公开(公告)日:2013-10-15
申请号:US13203697
申请日:2010-01-27
申请人: Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh , David Price
发明人: Peter Krulevitch , Robert Wilk , Ulrich Kraft , Donna Savage , Nick Foley , James Glencross , David Shepherd , Zara Sieh , David Price
CPC分类号: A61M5/315 , A61B5/002 , A61B5/14532 , A61M5/24 , A61M5/3129 , A61M5/3146 , A61M5/31525 , A61M5/31551 , A61M2005/3126 , A61M2005/3142 , A61M2205/14 , A61M2205/18 , A61M2205/215 , A61M2205/3317 , A61M2205/3553 , A61M2205/3561 , A61M2205/3569 , A61M2205/3584 , A61M2205/3592 , A61M2205/52 , A61M2205/581 , A61M2205/583 , A61M2205/584 , A61M2205/6054 , A61M2205/6081 , A61M2205/8212 , A61M2209/04 , G01D5/1655 , G06F19/00 , G06F19/3468
摘要: Various embodiments of a “smart” drug delivery system are provided which includes an add-on module and a reusable or disposable drug pen in conjunction with a data management unit(s) DMU. Upon attachment to the pen, the add-on module may: determine dosage selected, injection of selected dosage, duration of injection, time of injection, whether the pen has been primed or shaken to thoroughly mix up insulin mixtures, transmit information relating to insulin dosage and injection to a data management unit, provide reminders, error warning or messages on improper usage or reuse of needles, track amount of drug remaining on board the pen or duration of usage of pen with respect to expiry of the drug on board, or provide an audible alarm for locating misplaced pen and module. Methods of using the drug delivery system are also described.
摘要翻译: 提供了“智能”药物递送系统的各种实施例,其包括与数据管理单元DMU结合的附加模块和可重复使用或一次性药物笔。 附加模块可以:确定所选择的剂量,所选剂量的注射,注射持续时间,注射时间,笔是否被引发或摇动以充分混合胰岛素混合物,传送与胰岛素相关的信息 剂量和注射到数据管理单元,提供提醒,错误警告或关于针的不正确使用或重复使用的信息,笔上留下的药物的轨迹量或笔的使用持续时间,关于药物到期的时间,或 提供用于定位放错的笔和模块的声音报警器。 还描述了使用药物递送系统的方法。
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