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    Methods and devices for obstructing and aspirating lung tissue segments
    3.
    发明授权
    Methods and devices for obstructing and aspirating lung tissue segments 有权
    用于阻塞和吸入肺组织段的方法和装置

    公开(公告)号：US06527761B1

    公开(公告)日：2003-03-04

    申请号：US09699302

    申请日：2000-10-27

    申请人： Peter P. Soltesz ,  Robert Kotmel ,  Tony Wondka ,  Michael P. Reilly ,  Wally S. Buch

    发明人： Peter P. Soltesz ,  Robert Kotmel ,  Tony Wondka ,  Michael P. Reilly ,  Wally S. Buch

    IPC分类号： A61M3500

    CPC分类号： A61B17/12172 ,  A61B17/12022 ,  A61B17/12104 ,  A61B17/12136 ,  A61B17/12159 ,  A61B17/1219 ,  A61B2017/1205 ,  A61B2017/22067 ,  A61B2017/22068

    摘要： Methods, systems, devices and kits for performing lung volume reduction in patients suffering from chronic obstructive pulmonary disease or other conditions using and comprising minimally invasive instruments introduced through the mouth (endotracheally) to isolate a target lung tissue segment from other regions of the lung and reduce lung volume. Isolation is achieved by deploying an obstructive device in a lung passageway leading to the target lung tissue segment. Once the obstructive device is anchored in place, the segment can be aspirated through the device. This may be achieved by a number of methods, including coupling an aspiration catheter to an inlet port on the obstruction device and aspirating through the port. Or, providing the port with a valve which allows outflow of gas from the isolated lung tissue segment during expiration of the respiratory cycle but prevents inflow of air during inspiration. In addition, a number of other methods may be used. The obstructive device may remain as an implant, to maintain isolation and optionally allow subsequent aspiration, or the device maybe removed at any time.

    摘要翻译： 用于在患有慢性阻塞性肺病或其他病症的患者中进行肺容积减小的方法，系统，装置和试剂盒，其使用和包括通过口引入的微创器械（气管内）以将目标肺组织区段与肺的其他区域隔离， 减少肺容量。 通过在通向目标肺组织段的肺通道中展开阻塞装置来实现隔离。 一旦阻塞装置固定在适当位置，则可以通过装置吸入该段。 这可以通过许多方法来实现，包括将吸入导管联接到阻塞装置上的入口端口并通过端口抽吸。 或者，为端口提供阀，其允许在呼吸周期期间从隔离的肺组织段流出气体，但是防止在吸气期间空气的流入。 此外，可以使用许多其它方法。 阻塞装置可以保留为植入物，以保持隔离并且可选地允许随后的吸入，或者可以随时移除该装置。

    Intravascular catheter
    9.
    发明授权
    Intravascular catheter 失效
    血管内导管

    公开(公告)号：US5662622A

    公开(公告)日：1997-09-02

    申请号：US409973

    申请日：1995-04-04

    申请人： Susana M. Gore ,  Mark Mueller ,  Nicholas Green ,  Jeffrey G. Gold ,  Peter P. Soltesz

    发明人： Susana M. Gore ,  Mark Mueller ,  Nicholas Green ,  Jeffrey G. Gold ,  Peter P. Soltesz

    IPC分类号： A61M25/00 ,  A61M25/16

    CPC分类号： A61M25/0012 ,  A61M25/0053 ,  A61M25/0054 ,  Y10S264/52

    摘要： An intravascular catheter carries a helical reinforcement member embedded within at least a portion of the tubular wall of the catheter. The helical reinforcement member comprises a helical first portion having coils of greater pitch than the pitch of helical coils of a second portion. Preferably, the catheter is for insertion into brain arteries, and comprises a flexible tube having an outer diameter of no more that about 0.05 inch, for example 3 French or smaller. The flexible tube defines outer and inner tubular layers. The inner tubular layer surrounds a catheter lumen and comprises a chemically inert fluorinated polymer such as PTFE. The outer tubular layer comprises at least three longitudinally spaced, connected tubular sections. The sections are of successively increasing flexibility from the proximal toward the distal catheter end. Also, manufacturing methods are disclosed pertaining to increasing the flexibility of a section of the catheter and joining together in abutting relation a pair of dissimilar catheter reinforcement members.

    摘要翻译： 血管内导管承载嵌入在导管的管状壁的至少一部分内的螺旋加强构件。 螺旋加强构件包括螺旋形第一部分，其具有比第二部分的螺旋线圈的螺距更大的螺距的线圈。 优选地，导管用于插入脑动脉，并且包括具有不超过约0.05英寸（例如3 French French）或更小的外径的柔性管。 柔性管限定外部和内部管状层。 内部管状层围绕导管内腔并且包含化学惰性的氟化聚合物如PTFE。 外部管状层包括至少三个纵向间隔开的连接的管状部分。 这些部分从近端到远端导管末端依次增加的灵活性。 此外，公开了关于增加导管的一部分的柔性并且以对接关系将一对不同的导管加强构件接合在一起的制造方法。