公开(公告)号：US20120283364A1

公开(公告)日：2012-11-08

申请号：US13464209

申请日：2012-05-04

申请人： PIERRE SARAZIN ,  BASIL D. FAVIS

发明人： PIERRE SARAZIN ,  BASIL D. FAVIS

IPC分类号： C08L3/02

CPC分类号： C08L3/02 ,  C08K3/34 ,  C08K5/053 ,  C08L29/04 ,  C08L67/02 ,  C08L67/04 ,  C08L2205/02 ,  C08L2205/03

摘要： New polymer blends are provided. These blends comprise a first polymer, a second polymer and thermoplastic starch, the thermoplastic starch being at least partially encapsulated in the second polymer. The polymer blends may be shaped into articles, for example by extrusion or injection molding.

摘要翻译： 提供新的聚合物共混物。 这些共混物包含第一聚合物，第二聚合物和热塑性淀粉，热塑性淀粉至少部分地包封在第二聚合物中。 聚合物共混物可以成形为制品，例如通过挤出或注射成型。

公开(公告)号：US20070116737A1

公开(公告)日：2007-05-24

申请号：US10552357

申请日：2004-04-02

申请人： Basil Favis ,  Pierre Sarazin ,  Jiangming Li ,  Zhenhua Yuan

发明人： Basil Favis ,  Pierre Sarazin ,  Jiangming Li ,  Zhenhua Yuan

IPC分类号： A61F2/02

CPC分类号： A61L27/18 ,  A61L27/56 ,  A61L27/58 ,  C08L67/04

摘要： The present invention relates to a highly controlled method of preparation of a microporous biodegradable polymeric article. Firstly, at least one biodegradable polymer A, one polymer B, biodegradable or not, partially or totally immiscible with A, and a compatibilizer C for A and B are selected. Secondly, the selected polymers are melt-blended, thereby preparing a polymer blend; wherein said polymers A and B have an essentially continuous morphology. Thirdly, after cooling, polymer B and compatibilizer C are selectively extracted from the polymer blend by dissolution in a solvent that is a non-solvent of polymer A. The resulting polymeric article has an essentially continuous porosity with a void volume between 10 and 90% and a unimodal diameter distribution set to a predefined unimodal peak location. It can be used in tissue engineering, for controlled release applications or as an implantable medical device.

摘要翻译： 本发明涉及高度可控制的微孔可生物降解聚合物制品的方法。 首先，选择至少一种可生物降解的聚合物A，一种可生物降解的或不与A部分或完全不混溶的聚合物B，以及用于A和B的增容剂C。 其次，将所选择的聚合物熔融共混，由此制备聚合物共混物; 其中所述聚合物A和B具有基本连续的形态。 第三，冷却后，通过溶解在聚合物A的非溶剂的溶剂中，从聚合物共混物中选择性地提取聚合物B和增容剂C.所得的聚合物制品具有基本上连续的孔隙率，空隙体积为10至90％ 和单峰直径分布设置为预定义的单峰峰位置。 它可用于组织工程，控制释放应用或植入式医疗设备。

公开(公告)号：US20120184672A1

公开(公告)日：2012-07-19

申请号：US13349202

申请日：2012-01-12

申请人： DANUT RISCANU ,  PIERRE SARAZIN

发明人： DANUT RISCANU ,  PIERRE SARAZIN

IPC分类号： C08L67/04 ,  B29C47/00 ,  B29C51/02 ,  B29C45/00

CPC分类号： C08J3/226 ,  B29C48/0017 ,  B29C48/08 ,  B29C51/002 ,  B29C51/02 ,  B29C51/46 ,  B29K2067/046 ,  C08J2367/04 ,  C08J2467/04 ,  C08K3/34 ,  C08K5/0016 ,  C08L67/04

摘要： There is provided a polylactic acid resin composition having elevated impact resistance and/or elevated heat deflection temperature, the composition comprising polylactic acid as a major phase. There is also provided an article made of this composition and a masterbatch for producing this composition through dilution with polylactic acid. Finally, there is also provided a process for making such a composition, the process comprising the step of compounding together the following ingredients: polylactic acid, a mineral filler, a chain mobility additive, optionally an impact modifier, and optionally a chain extender, thereby producing the resin composition.

摘要翻译： 提供了具有升高的耐冲击性和/或升高的热变形温度的聚乳酸树脂组合物，该组合物包含聚乳酸作为主相。 还提供了由该组合物制成的制品和通过用聚乳酸稀释制备该组合物的母料。 最后，还提供了制备这种组合物的方法，该方法包括将以下成分混合在一起的步骤：聚乳酸，矿物填充剂，链移动性添加剂，任选的抗冲改性剂和任选的增链剂 生产树脂组合物。

公开(公告)号：US08007823B2

公开(公告)日：2011-08-30

申请号：US10552357

申请日：2004-04-02

申请人： Basil D. Favis ,  Pierre Sarazin ,  Jianming Li ,  Zhenhua Yuan

发明人： Basil D. Favis ,  Pierre Sarazin ,  Jianming Li ,  Zhenhua Yuan

IPC分类号： A61F2/00

CPC分类号： A61L27/18 ,  A61L27/56 ,  A61L27/58 ,  C08L67/04

摘要： The present invention relates to a highly controlled method of preparation of a microporous biodegradable polymeric article. Firstly, at least one biodegradable polymer A, one polymer B, biodegradable or not, partially or totally immiscible with A, and a compatibilizer C for A and B are selected. Secondly, the selected polymers are melt-blended, thereby preparing a polymer blend, wherein said polymers A and B have an essentially continuous morphology. Thirdly, after cooling, polymer B and compatibilizer C are selectively extracted from the polymer blend by dissolution in a solvent that is a non-solvent of polymer A. The resulting polymeric article has an essentially continuous porosity with a void volume between 10 and 90% and a unimodal diameter distribution set to a predefined unimodal peak location. It can be used in tissue engineering, for controlled release applications or as an implantable medical device.

摘要翻译： 本发明涉及高度可控制的微孔可生物降解聚合物制品的方法。 首先，选择至少一种可生物降解的聚合物A，一种可生物降解的或不与A部分或完全不混溶的聚合物B，以及用于A和B的增容剂C。 其次，将所选择的聚合物熔融共混，从而制备聚合物共混物，其中所述聚合物A和B具有基本连续的形态。 第三，冷却后，通过溶解在聚合物A的非溶剂的溶剂中，从聚合物共混物中选择性地提取聚合物B和增容剂C.所得的聚合物制品具有基本上连续的孔隙率，空隙体积为10至90％ 和单峰直径分布设置为预定义的单峰峰位置。 它可用于组织工程，控制释放应用或植入式医疗设备。

公开(公告)号：US20090087641A1

公开(公告)日：2009-04-02

申请号：US12093712

申请日：2006-11-14

申请人： Basil D. Favis ,  Pierre Sarazin ,  Xavier Roy

发明人： Basil D. Favis ,  Pierre Sarazin ,  Xavier Roy

IPC分类号： C08J9/26 ,  B32B3/26 ,  A61K47/30 ,  A61F2/02 ,  B01J31/06 ,  B01D39/14

CPC分类号： A61L27/56 ,  A61L27/18 ,  A61L2400/12 ,  B01D39/1676 ,  B01D2239/10 ,  B01J20/268 ,  B01J20/28097 ,  B01J20/305 ,  B01J20/3212 ,  B01J20/327 ,  B01J20/3272 ,  B01J20/3274 ,  B01J20/3289 ,  B01J2220/445 ,  C08J9/0061 ,  C08J9/26 ,  C08J2201/046 ,  C08J2367/02 ,  C08J2467/00 ,  Y10T428/249953 ,  C08L67/04

摘要： A method for making a porous material, includes melt-blending two or more non-miscible polymers to obtain a co-continuous melt, solidifying the melt to obtain a solid mass consisting of two co-continuous polymer phases, and selectively extracting one of the co-continuous phases thereby creating within the solid mass an essentially continuous pore network having an internal surface. The method further includes replicating the internal surface of the pore network within the solid mass by coating the internal surface with successive layers of materials, and selectively extracting the solid mass without extracting the layers of materials, to thereby yield the product porous material, formed of the layers of materials. The material has a void fraction higher than about 75%, and mainly having essentially fully interconnected sheath-like non-spherical pores and essentially non-fibrous walls.

摘要翻译： 制造多孔材料的方法包括熔融共混两种或更多种不相混合的聚合物以获得共连续熔体，使熔体固化，得到由两个共连续聚合物相组成的固体物质，并选择性地提取 共连续相，从而在固体物质内产生具有内表面的基本上连续的孔网络。 该方法还包括通过用连续的材料层涂覆内表面，在固体物质内复制孔网络的内表面，并且在不提取材料层的情况下选择性地提取固体物质，由此产生产物多孔材料，由 材料层。 该材料具有高于约75％的空隙率，并且主要具有基本上完全相互连接的鞘状非球形孔和基本上非纤维壁。

公开(公告)号：US08257624B2

公开(公告)日：2012-09-04

申请号：US12093712

申请日：2006-11-14

申请人： Basil D. Favis ,  Pierre Sarazin ,  Xavier Roy

发明人： Basil D. Favis ,  Pierre Sarazin ,  Xavier Roy

IPC分类号： B29C67/20

CPC分类号： A61L27/56 ,  A61L27/18 ,  A61L2400/12 ,  B01D39/1676 ,  B01D2239/10 ,  B01J20/268 ,  B01J20/28097 ,  B01J20/305 ,  B01J20/3212 ,  B01J20/327 ,  B01J20/3272 ,  B01J20/3274 ,  B01J20/3289 ,  B01J2220/445 ,  C08J9/0061 ,  C08J9/26 ,  C08J2201/046 ,  C08J2367/02 ,  C08J2467/00 ,  Y10T428/249953 ,  C08L67/04

摘要： A method for making a porous material, includes melt-blending two or more non-miscible polymers to obtain a co-continuous melt, solidifying the melt to obtain a solid mass consisting of two co-continuous polymer phases, and selectively extracting one of the co-continuous phases thereby creating within the solid mass an essentially continuous pore network having an internal surface. The method further includes replicating the internal surface of the pore network within the solid mass by coating the internal surface with successive layers of materials, and selectively extracting the solid mass without extracting the layers of materials, to thereby yield the product porous material, formed of the layers of materials. The material has a void fraction higher than about 75%, and mainly having essentially fully interconnected sheath-like non-spherical pores and essentially non-fibrous walls.

摘要翻译： 制造多孔材料的方法包括熔融共混两种或更多种不相混合的聚合物以获得共连续熔体，使熔体固化，得到由两个共连续聚合物相组成的固体物质，并选择性地提取 共连续相，从而在固体物质内产生具有内表面的基本上连续的孔网络。 该方法还包括通过用连续的材料层涂覆内表面，在固体物质内复制孔网络的内表面，并且在不提取材料层的情况下选择性地提取固体物质，由此产生产物多孔材料，由 材料层。 该材料具有高于约75％的空隙率，并且主要具有基本上完全相互连接的鞘状非球形孔和基本上非纤维壁。